Severity of Illness Caused by Severe Acute Respiratory Syndrome Coronavirus 2 Variants of Concern in Children: A Single-Center Retrospective Cohort StudyArticle Published on 2022-10-252022-11-16 Journal: Journal of the Pediatric Infectious Diseases Socie [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI age Alpha analyses children clinical Community concern coronavirus 2 COVID-19 COVID-19 infection COVID-19 severity diagnosed with COVID-19 FIVE Frequency Gamma Hospitalization ICU admission illness Illumina immunization incidence increasing age marker medical condition Medical conditions outcome outcomes performed pharmacologic treatment prevented recent Regression model respiratory Respiratory Support retrospective cohort study SARS-CoV-2 SARS-CoV-2 vaccination SARS-CoV-2 variant scale Sequencing severe COVID-19 severe disease severity Severity. single-center the WHO VoC VOCs were infected with COVID-19 [DOI] 10.1093/jpids/piac068 PMC 바로가기
Comparison of the kinetics and magnitude of antibody responses to different SARS-CoV-2 proteins in Sinopharm/BBIBP-CorV vaccinees following the BNT162b2 booster or natural infectionArticle Published on 2022-10-132022-11-15 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 진단, [키워드] ACE2 anti-RBD antibodies antibody Antibody Response BNT162b2 booster Cohort dose Frequency highest IgG antibody immune response implication individual infected individual Infection investigated lowest magnitude natural infection persistence post vaccination Protein receive remained robust S1 and S2 SARS-CoV-2 protein second dose significantly higher Sinopharm subsequent the N protein the RBD the SARS-CoV-2 virus total antibody uninfected vaccinee vaccinees were infected [DOI] 10.1371/journal.pone.0274845 PMC 바로가기
Factors influencing the SARS-CoV-2 infection and vaccination induced immune response in rheumatoid arthritisArticle Published on 2022-10-122022-11-15 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 진단, 치료기술, 치료제, [키워드] addition age anti-CD20 therapy anti-S anti-S antibody anti-SARS-CoV-2 antibodies antibody Antibody Response BNT162b2 cell-mediated response Cellular immune response cellular immune responses ChAdOx1 Concentration Corona covariate adjustment COVID-19 COVID-19 vaccine declined dependent on DMARD (disease-modifying antirheumatic drug treatment) domains dose enrolled Factor healthy controls humoral IL-6 inhibitor immune response Infection inhibited investigated IQR magnitude median time mRNA-1273 Patient patients patients treated peptides positive patient reduced respiratory rheumatoid arthritis RNA RNA vaccine SARS-CoV-2 significant effect significantly Specific specific antibodies specific antibody subject T-cell T-cell Response targeted therapy the healthy the interferon the SARS-CoV-2 the vaccine therapy vaccination vaccination. Vaccine variables was measured were infected [DOI] 10.3389/fimmu.2022.960001 PMC 바로가기
Transitional Changes in Fatigue-Related Symptoms Due to Long COVID: A Single-Center Retrospective Observational Study in JapanArticle Published on 2022-10-052022-11-16 Journal: Medicina [Category] COVID19(2023년), SARS, 변종, [키워드] 113 patient and post COVID-19 condition caused change changes in Characteristics characterized cough COVID COVID patient COVID-19 delta variant dysgeusia dysosmia fatigue Frequency hospitalizations illnesses Insomnia Japan Long manifestation material myalgic encephalomyelitis/chronic fatigue syndrome. objective omicron Omicron variant outpatient clinic Patient patients prevalent Result retrospective significantly significantly lower single-center Symptom syndrome the patient three groups university vaccination variant variants viral variant were infected [DOI] 10.3390/medicina58101393 PMC 바로가기
Investigation of healthcare-associated COVID-19 in a large French hospital group by whole-genome sequencing전체 게놈 시퀀싱에 의한 대규모 프랑스 병원 그룹의 의료 관련 COVID-19 조사Article Published on 2022-10-012022-09-11 Journal: Microbiological research [Category] COVID19(2023년), SARS, 치료기술, [키워드] 30-day mortality rate acute respiratory syndrome acute respiratory syndrome coronavirus Analysis assigned Cluster coronavirus correlated COVID-19 epidemiological Epidemiology evaluate Evolution examined exclusion France French Frequency group HCWs healthcare healthcare worker Healthcare workers Healthcare-associated infection hospital Hospitalized hospitalized patient hospitalized patients implementation incidence Infection infection control Infection prevention investigation many case many cases Mortality nosocomial COVID-19 Nosocomial transmission Paris Patient Personal protective equipment Prevention and control PROTECT reported SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 study period Transmission transmission route Transmission routes university were infected WGS Whole genome sequencing whole genome sequencing. whole-genome sequencing with COVID-19 [DOI] 10.1016/j.micres.2022.127133 PMC 바로가기 [Article Type] Article
Maternal and neonatal immune response to SARS-CoV-2, IgG transplacental transfer and cytokine profileArticle Published on 2022-09-272022-11-15 Journal: Frontiers in Immunology [Category] SARS, 진단, 치료기술, [키워드] 229E antibodies antibody Barcelona Blood blood sample C-terminus cause chemokine collected Concentration concentrations COVID-19 cytokine level cytokine levels cytokine profile cytokine response Cytokines distress domain EGF FGF full-length growth factor higher risk HKU1 human coronavirus Humoral response IFN-α IgA level IgG IgM IL-15 IL-17 IL-7 immune response immunological increased risk induce Infection Inflammatory investigated male Maternal maternal and neonatal immunity mother Neonatal Newborn NL63 non-infected nucleocapsid OC43 outcome outcomes positive positive correlation positive for rRT-PCR Pregnancy pregnant women Preterm birth profiles Questionnaires RANTES recruited reduction robust rRT-PCR SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 detection SARS-COV-2 infection SARS-CoV-2-specific IgG SARS-CoV-2-specific IgGs serology severe COVID-19 Spain Swab Symptom symptomatic tested transfer transplacental transfer. Vaccines variables was increased were infected were recorded women [DOI] 10.3389/fimmu.2022.999136 PMC 바로가기
Antibody titers among healthcare workers for coronavirus disease 2019 at 6 months after BNT162b2 vaccinationArticle Published on 2022-09-162022-11-15 Journal: Vaccine [Category] SARS, 진단, [키워드] acute respiratory syndrome age Analysis analyzed Anti-spike antibody antibody level Antibody titre BNT162b2 BNT162b2 vaccine Care conducted coronavirus disease coronavirus disease-2019 Coronavirus-2 COVID-19 decrease dose Factor female females healthcare healthcare worker Healthcare workers hospital IgG IgG antibody Japanese negative correlation participant Participants preserved Prospective Study Protein Regression SARS-CoV-2 side Side effects tested the vaccine vaccination vaccination. were infected [DOI] 10.1016/j.vaccine.2022.08.035 PMC 바로가기
Lipocalin-2 is an essential component of the innate immune response to Acinetobacter baumannii infectionArticle Published on 2022-09-022022-11-16 Journal: PLoS Pathogens [Category] 유전자 메커니즘, [키워드] Acinetobacter acquisition antimicrobial drug Bacteremia Bacterial bloodstream infection caused change characteristic COVID-19 pandemic Critical curtail dissemination essential nutrient evaluated exhibited expand expression expression pattern feasible gene encoding Gene Expression Gram-negative bacteremia growth Health healthcare homeostasis Host host gene expression Immunity impairment include induce Infection inhibit inhibiting innate immune response involved lack Lcn2 lipocalin-2 MDR mechanism mice Mortality multidrug resistant multifactorial organ organ-specific pathogen Pneumonia Prevalence proliferation Protective Protein required reveal robust S100A8 S100A9 secondary bacterial pneumonia sequestering survival target therapeutic tissues Transcription transcriptional Treatment upregulated ventilated patient Ventilator-associated pneumonia were infected World Health Organization [DOI] 10.1371/journal.ppat.1010809 PMC 바로가기
Effectiveness of Commonly Used Contact Lens Disinfectants Against SARS-CoV-2SARS-CoV-2에 대한 일반적으로 사용되는 콘택트 렌즈 소독제의 효과Article Published on 2022-09-012022-09-11 Journal: Eye & contact lens [Category] SARS, 치료기술, [키워드] absence acute respiratory syndrome Against applied Chain Reaction Contact contact lens detect disinfectant Disinfection Efficacy FIVE for disinfection Len PCR polymerase chain polymerase chain reaction regimen responsible reverse-transcriptase polymerase chain reaction rinsing RT-PCR SARS-CoV-2 SARS-CoV-2 RNA Severe Acute Respiratory Syndrome Corona Virus silicone tested time interval viability viral infectivity virus was tested were infected were used [DOI] 10.1097/ICL.0000000000000925 PMC 바로가기 [Article Type] Article
Mutations in the nonstructural proteins of SARS-CoV-2 may contribute to adverse clinical outcome in patients with COVID-19Research article Published on 2022-09-012022-10-05 Journal: International Journal of Infectious Diseases [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] Amino acid Clinical course Clinical outcome Cluster contribute COVID-19 enrolled FIVE genome sequence Infection mortality rate Mutation nonstructural protein Nsp15 Nsp3 oxygen flow rate Patient patients with COVID-19 positive Primary outcome required Result SARS-CoV-2 secondary outcome selective severity the disease the S protein two groups virulence were infected with COVID-19 [DOI] 10.1016/j.ijid.2022.05.010 [Article Type] Research article