Adaptive immunity – Page 20 – Communicable Diseases Research

Poliovirus Vaccination Induces a Humoral Immune Response That Cross Reacts With SARS-CoV-2

Medicine

Published on 2021-08-032022-10-31
Journal: Frontiers in Medicine [Category] COVID-19,

Antibody responses after first and second Covid-19 vaccination in patients with chronic lymphocytic leukaemia

만성 림프구 백혈병 환자에서 제 1 및 제 2 코비드 -19 백신 접종 후 항체 반응

Clinical Trial

Published on 2021-07-302022-08-09
Journal: Blood Cancer Journal [Category] 임상, 진단,

[키워드] Adaptive immunity Antibody Response Antibody responses Antibody titre antibody titres B-cell blood sample Blood samples BNT162b2 BNT162b2 mRNA vaccine booster vaccines BTK inhibitor BTK inhibitors ChAdOx1 Chronic lymphocytic leukaemia clinical risk CLL COVID-19 vaccines detectable dried blood spot Dried blood spots extended interval failure Filter Paper generate healthy donor healthy donors IgA deficiency Immunosuppression Multivariate analysis offer Patient profile remained SARS-COV-2 infection second vaccination Severe infection spike-specific antibody response Spike-specific antibody responses Support the antibody response the patient titre titres Translational research Treatment utility vaccination Vaccination strategy Vaccine venepuncture
[DOI] 10.1038/s41408-021-00528-x PMC 바로가기 [Article Type] Clinical Trial

Innate and Adaptive Immune Assessment at Admission to Predict Clinical Outcome in COVID-19 Patients

Article

Published on 2021-07-292022-10-28
Journal: Biomedicines [Category] COVID-19,

[키워드] activated adaptive Adaptive immunity Admission age antibody panel assessment Biomarker C-reactive protein carried CD27 CD28 CD38 CD8 cellular circulating clinical component COVID-19 COVID-19 disease COVID-19 pandemic D-dimer evaluate evaluated ferritin flow cytometry Frequency HLADR humoral IL-6 immune parameter immune response immune system immunological profile Innate Innate immunity Innate lymphoid cells interleukin-6 Logistic regression analysis lymphopenia Mild Mild symptom NK cells non-classical monocyte Non-classical monocytes Older Oxygen therapy Patient phenotype predicted Predictive Predictive model Prognosis prognostic biomarker Regulatory Regulatory T cell SARS-CoV-2 SARS-COV-2 infection severe disease Severe patient severity significantly increased Th1 the disease the patient
[DOI] 10.3390/biomedicines9080917 PMC 바로가기 [Article Type] Article

Immune responses to a single dose of the AZD1222/Covishield vaccine in health care workers

의료 종사자의 AZD1222/Covishield 백신 단일 용량에 대한 면역 반응

Article

Published on 2021-07-292022-09-10
Journal: Nature Communications [Category] SARS, 변종, 진단, 치료기술,

[키워드] ACE2 Adaptive immunity age and gender antibody antibody level antibody levels Antibody titer Antibody titers approval AZD1222 B.1.1.7 B.1.351 B.1.351 variant blocking antibodies carried Cohort COVID-19 vaccine dose ELISpot assay ELISpot assays Ex vivo HCW HCWs Health care Health care worker health care workers Health occupations healthcare worker Healthcare workers IFNγ immunogenicity large cohort naïve Neutralization assay PROTECT RBD Receptor binding domain response SARS-CoV-2 Seroconversion seroconvert seroconverted significantly higher single dose sub-cohort sVNT T cell T cell response the RBD titre titres Vaccine vaccine dose vaccinees Vaccines variant variants wild-type SARS-CoV-2 wild-type virus
[DOI] 10.1038/s41467-021-24579-7 PMC 바로가기 [Article Type] Article

Role of Immune Cells in Patients with Hepatitis B Virus-Related Hepatocellular Carcinoma

Review

Published on 2021-07-272023-06-03
Journal: International Journal of Molecular Sciences [Category] B형 간염,

[키워드] Adaptive immunity Hepatitis B virus Hepatocellular carcinoma immune balance immune cells Innate immunity
[DOI] 10.3390/ijms22158011 PMC 바로가기 [Article Type] Review

High-dimensional mass cytometry identifies T cell and B cell signatures predicting reduced risk of Plasmodium vivax malaria

고차원 질량 세포 분석은 Plasmodium vivax 말라리아의 위험 감소를 예측하는 T 세포 및 B 세포 서명을 식별합니다.

Research Article

Published on 2021-07-222024-08-08
Journal: JCI Insight [Category] 말라리아,

[키워드] Adaptive immunity immunology Infectious disease malaria
[DOI] 10.1172/jci.insight.148086 PMC 바로가기 [Article Type] Research Article

Durable Antibody Responses in Staff at Two Long-Term Care Facilities, during and Post SARS-CoV-2 Outbreaks

SARS-CoV-2 발생 동안 및 이후에 두 개의 장기 요양 시설 직원의 지속적인 항체 반응

Research Article

Published on 2021-07-212022-09-10
Journal: Microbiology Spectrum [Category] SARS, 진단, 치료기술,

[키워드] Adaptive immunity antibodies antibody binding Blood Care Case fatality rate collected contribute coronavirus correlated COVID-19 death detect evaluated facility Fatality rate Health Health care identify Immunity impacted infected individual infected individuals Infection infections Long-term care majority neutralization Neutralizing Neutralizing antibodies neutralizing antibody outbreak Outbreaks performed presymptomatic PROTECT Receptor-binding domain response SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 neutralizing antibodies SARS-CoV-2 spike protein Seroconversion seronegative Seroprevalence serum Spike protein Spread staff subsequent surveillance studies surveillance testing tested the receptor-binding domain the SARS-CoV-2 unique Workplace
[DOI] 10.1128/Spectrum.00224-21 PMC 바로가기 [Article Type] Research Article

Impaired humoral and cellular immunity after SARS-CoV-2 BNT162b2 (tozinameran) prime-boost vaccination in kidney transplant recipients

신장 이식 환자에서 SARS-CoV-2 BNT162b2(토지나메란) 프라임-부스트 백신 접종 후 체액 및 세포 면역 손상

Article

Published on 2021-07-152022-09-12
Journal: The Journal of Clinical Investigation [Category] SARS, 진단,

[키워드] accompanied Adaptive immunity Affect age analyzed antibody approach BNT162b2 booster caused CD4+ CD8+ T cell cellular immunity cellular response change combating Control COVID-19 cytokine production dialysis dose Frequency global pandemic healthy healthy control Hemodialysis humoral IgA IgG immune immunization immunology immunosuppressed patients Immunosuppressive medication Impaired impairment individual kidney transplant recipient less majority memory mounted mRNA-based vaccine novel organ transplantation Patient patients powerful tool promotion reduced rejection renal response responses risk SARS-CoV-2 SARS-CoV-2 BNT162b2 second vaccination Seroconversion severe COVID-19 significantly Still T cells T helper cell transplantation undetectable vaccination Vaccine-induced immunity vaccinee
[DOI] 10.1172/JCI150175 PMC 바로가기 [Article Type] Article

A Single-Cell Atlas of Lymphocyte Adaptive Immune Repertoires and Transcriptomes Reveals Age-Related Differences in Convalescent COVID-19 Patients

림프구 적응 면역 레퍼토리 및 전사체의 단일 세포 아틀라스는 회복기 COVID-19 환자의 연령 관련 차이를 보여줍니다

Comparative Study

Published on 2021-07-122022-09-11
Journal: Frontiers in Immunology [Category] SARS, 유전자 메커니즘,

[키워드] Activation adaptive Adaptive immune response Adaptive immunity age Analysis antibody Atla B cell B cell receptor B cell receptors B cells B lymphocytes BCR CD4 CD8 Cell cell receptor clearance clone convalescent COVID-19 patient convalescent COVID-19 patients COVID-19 COVID-19 disease COVID-19 patient Critical cytotoxicity dependent on difference effector elderly patients elevated GNLY groups GzmA GZMH IgA immune Immunity implicated knowledge lymphocyte Lymphocytes marker outcome Patient patients plasma Plasma cell PRF1 receptor repertoire SARS-CoV-2 Sequencing single-cell T and B cells T and B lymphocytes T cell TCRs Transcriptome transcriptomes transition VDJ repertoire
[DOI] 10.3389/fimmu.2021.701085 PMC 바로가기 [Article Type] Comparative Study

Twelve-month specific IgG response to SARS-CoV-2 receptor-binding domain among COVID-19 convalescent plasma donors in Wuhan

Article

Published on 2021-07-062022-10-04
Journal: Nature Communications [Category] SARS, 임상, 치료기술, 치료법,

[키워드] acute respiratory syndrome Adaptive immunity age antibodies antibody Antibody Response Antibody titer Antimicrobial responses convalescent convalescent COVID-19 patient convalescent plasma coronavirus coronavirus disease COVID-19 COVID-19 pandemic decrease Diagnosis domain Donor exceeded facilitate female Health humoral immune response IgG antibody IgG response immune memory Immunity initial male Neutralizing antibody titer older patient patients plasma plasma sample positive correlation positive rate promote reduce responses risk SARS-CoV-2 Spike protein the patient therapy Vaccine viral infection Wuhan Wuhan, China
[DOI] 10.1038/s41467-021-24230-5 PMC 바로가기 [Article Type] Article