Infection With the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Delta Variant Is Associated With Higher Recovery of Infectious Virus Compared to the Alpha Variant in Both Unvaccinated and Vaccinated Individuals중증 급성 호흡기 증후군 코로나바이러스 2(SARS-CoV-2) 델타 변이형 감염은 백신 접종을 받지 않은 사람과 백신을 맞은 사람 모두에서 알파 변이형에 비해 감염성 바이러스의 더 높은 회복률과 관련이 있습니다Major Article Published on 2021-12-182022-09-10 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 변종, 진단, 치료제, [키워드] (alpha acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Alpha Alpha variant anti-SARS-CoV-2 antibody Antiviral B.1.1.7 B.1.617.2 breakthrough infections Capital Capital Region Cell culture circulating clinical chart Cohort Comorbidities coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 correlated COVID-19 cycle threshold Delta delta variant disease severity greater transmissibility groups IgG IgG levels Immunoglobulin Immunoglobulin G increase in Increases increases in individual Infection infections Infectious virus Lineage Local nasal predominant Region respiratory Result SARS-CoV-2 SARS-CoV-2 IgG SARS-CoV-2 lineage severe acute respiratory syndrome Coronavirus significant increase significantly higher specimens symptomatic the median vaccinated individual vaccinated individuals vaccination variant variants Viral Viral RNA virus VoC Whole genome sequencing [DOI] 10.1093/cid/ciab986 PMC 바로가기 [Article Type] Major Article
Striking lineage diversity of severe acute respiratory syndrome coronavirus 2 from non-human sourcesResearch Paper Published on 2021-12-162022-10-28 Journal: One Health [Category] COVID-19, [키워드] acute respiratory syndrome Alpha variant Analysis animals bat Characteristics Cluster Clusters containment strategies coronavirus Delta Environment Felis FIVE Genetic Genome genomic highest hosts humans infecting investigated Lineage lineages majority Neovison Odocoileus pangolin pathogen Phylogenetic tree SARS-CoV-2 SARS-CoV-2 evolution SARS-CoV-2 genome sequences Spread strain Surveillance the SARS-CoV-2 transmission route variants of concern viral genome virus [DOI] 10.1016/j.onehlt.2021.100363 PMC 바로가기 [Article Type] Research Paper
Earlier In Vitro Viral Production With SARS-CoV-2 Alpha Than With Beta, Gamma, B, or A.27 Variants베타, 감마, B 또는 A.27 변이체보다 SARS-CoV-2 알파를 사용한 시험관 내 바이러스 생산 초기Cellular and Infection Microbiology Published on 2021-12-162022-09-11 Journal: Frontiers in Cellular and Infection Microbiology [Category] SARS, 변종, 진단, [키워드] A549 A549 cells Alpha Alpha variant antibody B.1.1.7 B.1.1.7 variant B.1.351 B.1.351 variant Beta change China France Gamma global public health global public health emergency in vitro infectious titres kinetic lineages neutralisation P.1 variant pandemic patients Production provide Replication replication cycle SARS-CoV-2 spike mutations Spread supernatants titre variant variants Vero E6 Viral Viral load [DOI] 10.3389/fcimb.2021.792202 PMC 바로가기 [Article Type] Cellular and Infection Microbiology
The Development of SARS-CoV-2 Variants: The Gene Makes the DiseaseReview Published on 2021-12-152022-10-29 Journal: Journal of Developmental Biology [Category] COVID-19, [키워드] accumulated mutation Affect affected Alpha variant antigenicity Beta caused characteristic concerning Contact COVID-19 COVID-19 vaccines D614G defined Deleterious delta variant described determine development E484K Effectiveness escape mutation functions Gamma genetic profile Human immune defense Immune escape initial knowledge L452R Lineage morbidity and mortality MOST Mutation mutations N501Y neutralizing antibodies (NAbs) Novel coronavirus nucleocapsid occurred other variants P681R pandemic prevalent Protein receptor binding domain (RBD) SARS-CoV-2 SARS-CoV-2 genome scrutiny severe respiratory disease severity Spike protein Spread synonymous T478K the disease the SARS-CoV-2 the Spike the spike protein Transmissibility unique Vaccines variant variant of concern (VOC) Variation viral fitness virus virus genome virus variant [DOI] 10.3390/jdb9040058 PMC 바로가기 [Article Type] Review
Comprehensive Contact Tracing, Testing and Sequencing Show Limited Transmission of SARS-CoV-2 between Children in Schools in Norway, August 2020 to May 2021Article Published on 2021-12-142022-10-29 Journal: Microorganisms [Category] COVID-19, [키워드] 95% CI acute respiratory syndrome All participant Alpha variant B.1.1.7 Child children Comprehensive Contact coronavirus COVID-19 eight enrolment had no Inconclusive index cases Infection prevention and control investigated Limited Lineage measure no significant difference Norway positive Saliva SARS-CoV-2 SARS-CoV-2 PCR SARS-CoV-2 transmission School Schools sequence identity sequenced Seven show Spread tested Testing Topic tracing Transmission transmission of SARS-CoV-2 variants viral strain whole genome Whole genome sequencing [DOI] 10.3390/microorganisms9122587 PMC 바로가기 [Article Type] Article
Increased transmissibility of SARS-CoV-2 lineage B.1.1.7 by age and viral load연령 및 바이러스 부하에 따른 SARS-CoV-2 계통 B.1.1.7의 전염성 증가Article Published on 2021-12-132022-09-10 Journal: Nature Communications [Category] SARS, 변종, 진단, [키워드] age Alpha Alpha variant association attack rate B.1.1.7 circulating Denmark dominant Epidemiology Establishing Households Increased Lineage Lineage B.1.1.7 lineages management Neutralizing antibodies New outcomes pandemic PCR test risk Risk factors SARS-CoV-2 strain test results Transmissibility transmissibility of SARS-CoV-2 variants of SARS-CoV-2 Viral viral infection Viral load were infected [DOI] 10.1038/s41467-021-27202-x PMC 바로가기 [Article Type] Article
Expected Evolution of COVID-19 Epidemic in France for Several Combinations of Vaccination Strategies and Barrier MeasuresArticle Published on 2021-12-102022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] agent-based model Alpha variant barrier caused Consequences Coverage COVID-19 death decision support techniques Efficiency Evolution France French Health highest ICU increase in International mandatory measure Measures Mortality outbreak public health Spread Strategy the epidemic the SARS-CoV-2 virus vaccinate vaccination Vaccination strategy variants virus variant would increase [DOI] 10.3390/vaccines9121462 PMC 바로가기 [Article Type] Article
Direct comparison of antibody responses to four SARS-CoV-2 vaccines in Mongolia몽골의 4가지 SARS-CoV-2 백신에 대한 항체 반응의 직접 비교Observational Study Published on 2021-12-082022-09-11 Journal: Cell Host & Microbe [Category] MERS, SARS, 변종, 유전자 메커니즘, 임상, 진단, [키워드] Alpha Alpha variant antibody Antibody Response Antibody responses Antibody testing Antibody titer Antibody titers approved AstraZeneca blocking activity caused collected comparison COVID-19 Direct individual Infection Mongolia Mongolian nine participant Pfizer Pfizer/BioNTech plasma Protein Public health intervention Public health interventions RBD RBD-ACE2 Receptor binding domain reported SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccine SARS-CoV-2 viral serology Sinopharm specimen Sputnik V stimulate stimulated the antibody response These data vaccination Vaccine vaccine responses Vaccines variant Viral Viral variants [DOI] 10.1016/j.chom.2021.11.004 PMC 바로가기 [Article Type] Observational Study
Adherence and sustainability of interventions informing optimal control against the COVID-19 pandemic Research Published on 2021-12-062022-10-05 Journal: Communications Medicine [Category] 변종, 치료기술, [키워드] adherence Alpha variant approach circulation COVID-19 mitigation COVID-19 pandemic data-driven detrimental distress effective Efficacy estimates European country Focusing France identify intensity Intervention lockdown lockdowns long-lasting moderate pandemic Quality of life remained Result risk social distancing sustained vaccination [DOI] 10.1038/s43856-021-00057-5 [Article Type] Research
Systemic Anti-Cancer Therapy and Metastatic Cancer Are Independent Mortality Risk Factors during Two UK Waves of the COVID-19 Pandemic at University College London HospitalArticle Published on 2021-12-022022-10-31 Journal: Cancers [Category] COVID-19, [키워드] age Alpha variant Analysis anti-cancer treatment anti-cancer treatments association B.1.1.7 B.1.1.7 SARS-CoV-2 variant Cancer co-morbidities co-morbidity Cohort COVID-19 COVID-19 hospitalization COVID-19 in patient COVID-19 pandemic death demographics demonstrated determinant determine Effect evaluated Factor First wave hospital hospitalized patients Immunosuppression increased mortality increased risk independent risk factor London lower mortality metastatic metastatic cancer metastatic disease Mortality outcome Patient patients treated Patients with cancer presenting Retrospective analysis risk risk factor Risk factors SARS-COV-2 infection second wave simple solid cancer systemic systemic anti-cancer therapy United Kingdom University College London variable was performed Wave with COVID-19 [DOI] 10.3390/cancers13236085 PMC 바로가기 [Article Type] Article