Identification of antiviral antihistamines for COVID-19 repurposing
COVID-19 용도 변경을 위한 항바이러스성 항히스타민제 식별
Article
Published on
Journal: Biochemical and Biophysical Research Communication [Category] SARS, 신약개발, 유전자 메커니즘, 치료제,
Journal: Biochemical and Biophysical Research Communication [Category] SARS, 신약개발, 유전자 메커니즘, 치료제,
[키워드] ACE2
adjuvant therapy
age
angiotensin
angiotensin converting enzyme
Angiotensin converting enzyme-2
Antihistamine
Antihistamines
Antiviral
antiviral activity
Antiviral effect
antiviral effects
approved drug
approved drugs
azelastine
benefit
candidate
clinical
Clinical studies
COVID-19
COVID-19 patients
diphenhydramine
disease
docking
Effectiveness
Electronic health record
Electronic health records
enzyme
greater
Histamine
hydroxyzine
identification
identify
IMPROVE
in vitro
in vitro activity
incidence
Intervention
ligands
mechanism
outcome
Prevent
receptor
Receptor binding
reduced
Repurposed drug
Repurposed drugs
repurposing
safety profile
SARS-CoV-2
SARS-COV-2 infection
SARS-CoV-2 positivity
severe COVID-19
sigma
sigma-1 receptor
subject
tested
therapy
Treatment
Usage
[DOI] 10.1016/j.bbrc.2020.11.095 PMC 바로가기 [Article Type] Article
[DOI] 10.1016/j.bbrc.2020.11.095 PMC 바로가기 [Article Type] Article