Increased frequency of porcine epidemic diarrhea virus shedding and lesions in suckling pigs compared to nursery pigs and protective immunity in nursery pigs after homologous re-challengeResearch Article Published on 2016-11-212022-10-28 Journal: Veterinary Research [Category] Coronavirus, [키워드] age assigned cause Clinical sign Course disease epidemic diarrhea euthanized fecal Frequency group groups homologous IgA antibody IgG level Increased Infection initial lesion less naïve PEDV pig populations protective immunity Randomly RNA seroconverted Spread the disease Typical virus while [DOI] 10.1186/s13567-016-0402-5 PMC 바로가기 [Article Type] Research Article
Isolation and characterization of porcine epidemic diarrhea virus associated with the 2014 disease outbreak in Mexico: case reportResearch Article Published on 2016-06-292022-10-28 Journal: BMC veterinary research [Category] Coronavirus, [키워드] acute infection amplification Analysis Case report caused characterization characterized clinical sample Clinical sign Clinical signs Culture Cytopathic effect disease epidemic diarrhea histological homology identify initial interest isolate Isolation lesion Mexico Microscopy molecular Mortality mortality rate necropsy nucleotide sequence observation outbreak PEDV Porcine epidemic diarrhea virus Protein Result RT-PCR S glycoprotein Sequencing staining state TCID the United State trypsin USA Vero Cell Virological virus virus particle was determined was performed [DOI] 10.1186/s12917-016-0763-z PMC 바로가기 [Article Type] Research Article
Assessment of pathogenicity and tissue distribution of infectious bronchitis virus strains (Italy 02 genotype) isolated from moroccan broiler chickensResearch Article Published on 2016-06-082022-10-28 Journal: BMC veterinary research [Category] Coronavirus, [키워드] affecting age amplification assessment bronchitis Cell chicken Clinical scoring Clinical sign conducted demonstrated distribution dominant epithelial hyperplasia exhibited four groups Genotype group groups histological induce infected organ Infectious Bronchitis Virus Infectious bronchitis virus (IBV) Inflammatory information inoculated Italy Italy 02 kidney kidney damage lamina propria lesion lesions lethargic lung macroscopic mass vaccination Massachusetts Morocco Mortality mucosal pathogen Pathogenecity Pathogenesis pathogenicity Post-infection Randomly Real-time PCR reported Respiratory disease Respiratory system Result serological response strain tested tissue tracheal Vaccine viral disease Viral RNA virus viruses were recorded [DOI] 10.1186/s12917-016-0711-y PMC 바로가기 [Article Type] Research Article
Replication and shedding of MERS-CoV in Jamaican fruit bats ( Artibeus jamaicensis )Article Published on 2016-02-222022-10-29 Journal: Scientific Reports [Category] Coronavirus, MERS, [키워드] bat cells cellular change Clinical sign Dipeptidyl peptidase 4 disease DPP4 Evidence expression Gene Expression highlight histopathological Hypothesis Infection inoculated intestinal tract intrinsic investigated investigation Jamaican fruit bat lung Lungs maintain MERS-CoV Middle East moderate receptor replicate replicated reservoir respiratory syndrome coronavirus spike glycoprotein Virus shedding zoonotic [DOI] 10.1038/srep21878 PMC 바로가기 [Article Type] Article
Experimental feline enteric coronavirus infection reveals an aberrant infection pattern and shedding of mutants with impaired infectivity in enterocyte culturesArticle Published on 2016-01-292022-10-29 Journal: Scientific Reports [Category] Coronavirus, MERS, [키워드] abnormality absence affected antibody blood cell CD8 Clinical sign Clinical signs coronavirus Coronavirus infection Culture Feline infectious peritonitis Hypothesis Immune cell immunological infect Infection Infectious virus intestinal investigated less leukocyte Mild mutant mutated Mutation mutations neutralising antibody not different occurred raise regulatory T cells Replication reveal SPF these cell Viraemia viral genome Virological virus [DOI] 10.1038/srep20022 PMC 바로가기 [Article Type] Article
Emergence of porcine epidemic diarrhea virus in southern GermanyCase Report Published on 2015-07-022022-10-28 Journal: BMC veterinary research [Category] Coronavirus, MERS, [키워드] affected affecting all age group Analysis Asia Blood Case report caused circulating Clinical sign country current Deletion diarrhea distribution emergence enteric disease Epidemic epidemic diarrhea Europe European Evidence full-length Genome Germany high mortality identity indicate information insertion isolate Mortality no increase nucleotide occurred outbreak over PEDV Phylogenetic analysis Porcine epidemic diarrhea virus producing reached reduction reported RT-qPCR S gene S INDEL PEDV S-gene significantly small intestine Southern Germany strain Strains the United State variant virulence virus watery while [DOI] 10.1186/s12917-015-0454-1 PMC 바로가기 [Article Type] Case Report
Replication and Shedding of MERS-CoV in Upper Respiratory Tract of Inoculated Dromedary CamelsResearch Published on 2014-12-012022-10-31 Journal: Emerging Infectious Diseases [Category] Coronavirus, MERS, [키워드] Camel camel-to-human transmission Camels Clinical sign coronavirus Dromedary experimental explain help Human Infection Infectious virus inoculated inoculation lack MERS-CoV MERS-CoV infection Middle East Middle East respiratory syndrome nasal Novel coronavirus respiratory respiratory syndrome coronavirus secretion severe respiratory disease shedding Support Symptom systemic illness the mean tract Transmission upper upper respiratory tract Viral RNA virus viruses zoonoses zoonosis zoonotic transmission [DOI] 10.3201/eid2012.141280 PMC 바로가기 [Article Type] Research
An evaluation of a liquid antimicrobial (Sal CURB®) for reducing the risk of porcine epidemic diarrhea virus infection of naïve pigs during consumption of contaminated feedResearch Article Published on 2014-09-252022-10-28 Journal: BMC veterinary research [Category] Coronavirus, [키워드] addition bioassay Clinical sign Contamination diarrhea Epidemic epidemic diarrhea Evidence Feed formaldehyde in vivo Infection initial libitum naïve negative control PEDV Porcine positive control provide reduce reducing Research Result risk risk factor Sal CURB® Salmonella Spread study period treated USA viral shedding virus virus infection vomiting [DOI] 10.1186/s12917-014-0220-9 PMC 바로가기 [Article Type] Research Article
An evaluation of contaminated complete feed as a vehicle for porcine epidemic diarrhea virus infection of naïve pigs following consumption via natural feeding behavior: proof of conceptResearch Article Published on 2014-08-052022-10-28 Journal: BMC veterinary research [Category] Coronavirus, MERS, [키워드] affected bioassay Clinical sign clinically Complete controls diarrhea Epidemic epidemic diarrhea experiment Feed in vivo Infection initial Initially intestinal lesion naïve negative negative control no evidence of PCR PEDV Porcine positive Result risk risk factor RNA Spread Support Transmission viral shedding virus virus infection vomiting was tested were used [DOI] 10.1186/s12917-014-0176-9 PMC 바로가기 [Article Type] Research Article
The Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Does Not Replicate in Syrian HamstersResearch Article Published on 2013-07-022022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] animal model Arabian Peninsula Clinical sign cytokine upregulation disease Efficacy hamster hamsters histological human-to-human transmission inoculated Intervention lesions MERS-CoV Middle East Novel coronavirus Pathogenesis replicate reported respiratory Seroconversion severe respiratory disease virus virus replication [DOI] 10.1371/journal.pone.0069127 PMC 바로가기 [Article Type] Research Article