Long-term time trends in reactivated herpes simplex infections and treatment in Swedenarticle Published on 2022-06-152024-09-02 Journal: BMC Infectious Diseases [Category] 대상포진, [키워드] Antiviral agents Apolipoprotein E4 cohort study Epidemiology herpes simplex Seroprevalence Ultraviolet radiation [DOI] 10.1186/s12879-022-07525-w PMC 바로가기 [Article Type] article
Glycaemic variability is associated with all-cause mortality in COVID-19 patients with ARDS, a retrospective subcohort study Research Published on 2022-06-142022-10-05 Journal: Scientific Reports [Category] 바이오마커, 임상, 치료법, [키워드] Aachen acute respiratory distress adjusted all-cause mortality ARDS caused clinically cohort study confounders Continuous coronavirus disease COVID-19 COVID-19 mortality COVID-19 patient death diabete diabetes elevated Factor Germany Glucose high mortality ICU ICU admission increase in intensive care Kaplan–Meier estimator likelihood mechanical ventilation median Metrics moderate Mortality mortality risk P/F ratio Patient patients with COVID-19 plasma procalcitonin retrospective severe ARDS significant increase statistically significant difference survival syndrome university Variability with COVID-19 [DOI] 10.1038/s41598-022-13816-8 [Article Type] Research
Clinical Severity of SARS-CoV-2 Omicron Variant Compared with Delta among Hospitalized COVID-19 Patients in Belgium during Autumn and Winter Season 2021-20222021-2022년 가을 및 겨울 시즌 동안 벨기에의 입원한 COVID-19 환자 중 델타와 비교한 SARS-CoV-2 오미크론 변이의 임상 심각도Multicenter Study Published on 2022-06-142022-09-11 Journal: Viruses [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI added adjusted Admission Analysis Belgium clinical cohort study Combination Comorbidities confounder COVID-19 COVID-19 pathogenesis COVID-19 patient Delta delta variant demographics genomic genomic data Genomic surveillance hospital Hospital mortality hospitalized patient hospitalized patients ICU ICU admission in-hospital mortality intensive care intensive care unit multifactorial multivariable logistic regression Multivariable logistic regression analysis National not significantly different omicron Omicron variant recognize retrospective risk SARS-CoV-2 SARS-CoV-2 variant season severe COVID-19 severity significantly lower study population Surveillance the SARS-CoV-2 vaccination Vaccination Status variant were infected Winter [DOI] 10.3390/v14061297 PMC 바로가기 [Article Type] Multicenter Study
Associations of sleep and circadian phenotypes with COVID-19 susceptibility and hospitalization: an observational cohort study based on the UK Biobank and a two-sample Mendelian randomization studyObservational Study Published on 2022-06-132022-10-05 Journal: Sleep [Category] 임상, [키워드] 95% CI 95% confidence interval addition analyses Analysis calculated causal link CIs Cohort cohort study conducted coronavirus disease COVID-19 COVID-19 hospitalization COVID-19 susceptibility decrease Diseases Effect Evidence Genetic Habitual Hospitalization hospitalized COVID-19 increased risk Insomnia Intervention IVW mendelian randomization MR analyses MR-Egger multivariable observation Observational cohort study outcome outcomes phenotype risk risk ratio RRs selected severe COVID-19 Sleep Support supported susceptibility Symptom UK biobank weighted median Weighting with COVID-19 [DOI] 10.1093/sleep/zsac003 PMC 바로가기 [Article Type] Observational Study
Increased risk of severe COVID-19 in hospitalized patients with SARS-CoV-2 Alpha variant infection: a multicentre matched cohort studySARS-CoV-2 알파 변종 감염으로 입원한 환자에서 심각한 COVID-19 위험 증가: 다기관 일치 코호트 연구Multicenter Study Published on 2022-06-132022-09-11 Journal: BMC Infectious Diseases [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI Admission age Alpha variant Analysis both groups cohort study Comorbidities Comorbidity conducted COVID-19 Data collection defined Factor France higher odd higher odds Hospitalization Hospitalized hospitalized patient hospitals in both group Increased lineages logistic regression model male median age multicentre non-rebreather mask participant Patient patients hospitalized primary endpoint proportion retrospective risk SARS-CoV-2 severe COVID-19 severity severity of COVID-19 Sex stratified the disease variant Variant of concern Alpha. VoC [DOI] 10.1186/s12879-022-07508-x PMC 바로가기 [Article Type] Multicenter Study
Early dexamethasone use as a protective measure in non-mechanically ventilated critically ill patients with COVID-19: a multicenter, cohort study Research Published on 2022-06-132022-10-05 Journal: Scientific Reports [Category] 임상, 치료법, [키워드] 1:1 24 hour benefit cohort study consequence COVID-19 COVID19 Critically ill patient debatable Dexamethasone higher odd hospital ICU admission ICUs in-hospital mortality initiated intensive care unit LOS mechanical ventilation Mortality multicenter multicenter cohort study outcome Patient patients with COVID-19 Prevent primary endpoint Propensity score Protective required Respiratory failure SOFA score statistically significant the timing Tocilizumab two group Ventilated ventilated patients was used with COVID-19 [DOI] 10.1038/s41598-022-13239-5 [Article Type] Research
Dynamic blood oxygen indices in mechanically ventilated COVID-19 patients with acute hypoxic respiratory failure: A cohort studyObservational Study Published on 2022-06-102022-10-04 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 임상, [키워드] Admission adult COVID-19 patient adult COVID-19 patients age AHRF analysed averaged baseline characteristics Blood blood oxygen BMI changes in Clinical outcome clinical outcomes clinical variable cohort of patient cohort study collected COVID-19 COVID-19 patient COVID-19 patients dynamic evaluate evaluated exhibited exploratory study hallmark help homogenous hypoxaemia hypoxic hypoxic respiratory failure IMPROVE intensive care Invasive mechanical ventilation IQR kPa less majority mean difference mechanical ventilation mechanically ventilated men morbidity and mortality non-survivor Non-survivors Observational cohort study offer outcome oxygen PaO2 PaO2/FiO2 ratio Patient performed retrospective Severe COVID-19 pneumonia significantly higher significantly lower supplementary oxygen survival survivor therapy understanding unique while [DOI] 10.1371/journal.pone.0269471 PMC 바로가기 [Article Type] Observational Study
Early outcomes in adults hospitalized with severe SARS-CoV-2 infection receiving tocilizumab중증 SARS-CoV-2 감염으로 입원하여 토실리주맙을 투여받은 성인의 조기 결과Article Published on 2022-06-102022-09-12 Journal: Medicina clínica [Category] COVID19(2023년), SARS, 진단, [키워드] 95% CI Administered administration Admission adults hospitalized age ARDS Barcelona baseline Charlson index cohort study consecutive patient COVID-19 COVID19 Critical disease dose Endpoint English hazard hazard ratio Hebron IL6 Immonomodulation immune system Infection Inmunomodulación intensive care IQR Lung injury male media Mortality Neumonía viral New coronavirus outcome oxygen supplementation Patient patients patients with COVID-19 Pneumonia Preliminary data Prevent primary endpoint receiving respiratory SARS-CoV-2 SARS-COV-2 infection secondary severe SARS-CoV-2 Spain Spanish symptom onset the median Tocilizumab tocilizumab administration treated treatment with tocilizumab university Viral pneumonia [DOI] 10.1016/j.medcli.2021.06.012 PMC 바로가기 [Article Type] Article
Outcomes of patients with ST-segment myocardial infarction admitted during the COVID-19 pandemic : A prospective, observational study from a tertiary care center in GermanyObservational Study Published on 2022-06-012022-10-05 Journal: Herz [Category] COVID19(2023년), SARS, 임상, [키워드] 30-Day mortality Admission Ausbruch Care clinical cohort study conducted Contact COVID-19 COVID-19 group COVID-19 pandemic Ejection fraction Emergency Emergency medical services English enrolled Epidemiology Germany greater Healthcare professional LVEF medical service medical services Mortality Myocardial Myocardial infarction outbreak outcome outcomes pandemic Patient public health reported SARS-CoV‑2 significantly significantly higher significantly lower significantly more STEMI Support TIMI ventricular were assessed [DOI] 10.1007/s00059-021-05058-7 PMC 바로가기 [Article Type] Observational Study
Cytokine release syndrome-like serum responses after COVID-19 vaccination are frequent and clinically inapparent under cancer immunotherapy Research Published on 2022-06-012022-10-05 Journal: Nature cancer [Category] 임상, 진단, 치료기술, 치료법, [키워드] 95% CI absence Adverse adverse event analyzed Cancer Cancer immunotherapy Cancer therapy clinically Cohort cohort study common condition COVID-19 vaccination COVID-19 vaccines CRS CXCL8 cytokine level Cytokine release syndrome Cytokines Diagnosis eight elevated event Hospitalized immune immune response immune-checkpoint inhibitor interleukin-6 modulate observé occurred Patient patients died receive response Serious Adverse Event serum serum cytokine single-center Symptoms therapy Treatment Tumor upregulated vaccination [DOI] 10.1038/s43018-022-00398-7 [Article Type] Research