Increased transmission of SARS-CoV-2 in Denmark during UEFA European championshipsUEFA 유럽 선수권 대회 기간 동안 덴마크에서 SARS-CoV-2 전파 증가Article Published on 2022-03-232022-09-11 Journal: Epidemiology and Infection [Category] SARS, 변종, [키워드] adjusted B.1.1.7 B.1.617.2 Cohort cohort study conducted connection Contact tracing contributed covariate covariates declining Delta Denmark dominant Epidemiology European event Hypothesis incidence rate Increased information Lineage mass events National occurred positive public health rate ratio reduced replacement SARS-CoV-2 SARS-CoV-2 test Support These data tournament Transmission transmission of SARS-CoV-2 transmissions vaccination rate vaccination rates was collected were used whole-genome sequencing [DOI] 10.1017/S095026882200019X PMC 바로가기 [Article Type] Article
Comparative effectiveness of the BNT162b2 and ChAdOx1 vaccines against Covid-19 in people over 5050세 이상의 사람들에서 Covid-19에 대한 BNT162b2 및 ChAdOx1 백신의 비교 효과Article Published on 2022-03-212022-09-11 Journal: Nature Communications [Category] SARS, 변종, 임상, 치료법, [키워드] 95% CI BNT162b2 booster ChAdOx1 ChAdOx1 vaccine Comparative Cox model delta variant dominant dose Effectiveness Efficacy hazard ratio head Head-to-head comparison hospitalisation Infection inverse lower risk mRNA of BNT162b2 Older participant persist Population Probability risk SARS-COV-2 infection study period Trial UK biobank vaccination Vaccine Vaccines Weighting [DOI] 10.1038/s41467-022-29159-x PMC 바로가기 [Article Type] Article
An Upgrade on the Surveillance System of SARS-CoV-2: Deployment of New Methods for Genetic InspectionSARS-CoV-2의 감시 시스템 업그레이드: 유전자 검사를 위한 새로운 방법 배포Article Published on 2022-03-152022-09-11 Journal: International Journal of Molecular Sciences [Category] SARS, 변종, 치료기술, [키워드] Abnormal result Analysis analyzed consensus sequence country delta variant dominant equipment faster Genetic genetic surveillance information Inspection lack Mutation mutations New next generation sequencing NGS option Population positive qPCR qPCR variant screening. reported RT-qPCR SARS-CoV-2 SARS-CoV-2 epidemiology SARS-CoV-2 sequence SARS-CoV-2 sequences SARS-CoV-2 surveillance SARS-CoV-2 variant SARS-CoV-2 variant identification screening test sequenced Surveillance System Upgrade variant variants [DOI] 10.3390/ijms23063143 PMC 바로가기 [Article Type] Article
Protective Immunity of the Primary SARS-CoV-2 Infection Reduces Disease Severity Post Re-Infection with Delta Variants in Syrian Hamsters1차 SARS-CoV-2 감염의 보호 면역은 시리아 햄스터의 델타 변종으로 재감염 후 질병 심각도를 감소시킵니다Article Published on 2022-03-132022-09-11 Journal: Viruses [Category] SARS, 변종, [키워드] acute respiratory syndrome AY.1 B.1 caused Characteristics characterized coronavirus disease Coronavirus disease 2019 Delta Delta AY.1 delta variant disease disease severity dominant dose Evidence evidence of groups hamster hamsters high viral load Immunity Infection initial interstitial pneumonia K417N K417N mutation lineages Lung disease Mild Mild disease neutralization Neutralizing neutralizing antibody pathogenicity produced re-infected Re-infection Re-infections reduce reduced reduction in Reinfection remained respiratory respiratory tract SARS-CoV-2 SARS-CoV-2 lineage Severe acute respiratory syndrome severe acute respiratory syndrome coronavirus-2 sterilizing immunity Syrian hamsters the disease upper upper respiratory tract variant variants Viral load viral RNA load virus [DOI] 10.3390/v14030596 PMC 바로가기 [Article Type] Article
Effectiveness of Covid-19 Vaccines over a 9-Month Period in North Carolina노스캐롤라이나에서 9개월 동안의 Covid-19 백신의 효과Article Published on 2022-03-102022-09-11 Journal: The New England Journal of Medicine [Category] SARS, 변종, [키워드] 95% CI 95% confidence interval Ad26 Ad26.COV2.S B.1.617.2 BNT162b2 caused coronavirus disease Coronavirus disease 2019 COV2.S Cox regression model death declining delta variant dominant dose Effectiveness elapsed first dose Hospitalization Immunity increase in Infection Messenger RNA Moderna mRNA mRNA vaccine mRNA-1273 North of BNT162b2 outcome Period Pfizer-BioNTech postvaccination preventing infection provided recipient reducing regimen risk summer System the United State two-dose regimen United States vaccination Vaccine variant Viral particles [DOI] 10.1056/NEJMoa2117128 PMC 바로가기 [Article Type] Article
Rapid SARS-CoV-2 Adaptation to Available Cellular Proteases사용 가능한 세포 프로테아제에 대한 신속한 SARS-CoV-2 적응Article Published on 2022-03-092022-09-11 Journal: Journal of Virology [Category] SARS, 변종, 유전자 메커니즘, [키워드] adaptation Alpha Alpha variant B.1.1.529 B.1.1.7 B.1.617.2 binding cathepsin Cathepsins cleavage clinical isolates conditions Consensus coronavirus coronavirus spike priming deep sequencing delta variant dominant Efficiency Evolution furin furin cleavage motif furin cleavage site Genome genomes genomic Genotype growth heparan sulfate highlight human cell human cells identify independent inhibit isolate isolates lack mechanism minor motif mutated Omicron variant processed protease Proteases Rapid recent S1/S2 site SARS-CoV-1 SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants selection pressure selective sequence spike mutation spike mutation. Spike protein spike protein of SARS-CoV-2 spike variant stability subpopulation sulfate Surveillance the spike protein These cells TMPRSS2 variant variants Vero Vero E6 Vero E6 cell VERO E6 cells virus virus growth virus pathogenesis wild type [DOI] 10.1128/jvi.02186-21 PMC 바로가기 [Article Type] Article
The IgA in milk induced by SARS-CoV-2 infection is comprised of mainly secretory antibody that is neutralizing and highly durable over timeResearch Article Published on 2022-03-092022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] Analysis antibody binding Care controls COVID-19 COVID-19 illness COVID-19 sample dominant Donor Endpoint exhibited exhibiting human milk IgA IgA antibody IgA titer IgG response immunization Infant Infants infected with SARS-CoV-2 Infection Level mucosal neutralization neutralization capacity Neutralizing Participants positive positively correlated potential mechanism Prevalence PROTECT Protective public health reported robust SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2-specific antibody secretory IgA shown subset tested therapeutic VSV [DOI] 10.1371/journal.pone.0249723 PMC 바로가기 [Article Type] Research Article
Was Alpha deadlier than wild-type COVID? Analysis in rural EnglandOriginal Paper Published on 2022-03-052022-10-29 Journal: Infection [Category] COVID-19, COVID19(2023년), MERS, SARS, 변종, [키워드] age Alpha variant Analysis B.1.1.7 calculated Case fatality rate case fatality rates conducted COVID-19 Deceased Deprivation diagnosed Diagnosis disease outbreak dominant England English Epidemiology Factors First wave less Logistic regression Male sex Marginal median age medical need Mortality mortality rate mortality risk multivariate observational study pandemic positive potential risk Probability raised Result risk Risk factors SARS-CoV-2 SARS-CoV-2 variant second wave Sex supplementary material tested variant was performed wild-type [DOI] 10.1007/s15010-022-01787-x PMC 바로가기 [Article Type] Original Paper
Antibody escape and global spread of SARS-CoV-2 lineage A.27SARS-CoV-2 계통의 항체 탈출 및 글로벌 확산 A.27Article Published on 2022-03-032022-09-11 Journal: Nature Communications [Category] MERS, SARS, 변종, 유전자 메커니즘, 진단, 치료기술, 치료제, [키워드] Amino acid amino acid substitution amino acid substitutions Analysis Antibody-mediated immunity bamlanivimab caused characterized convalescent D614G database described dominant escape Evolution Germany Immunity include independent Infection International L18F L452R lack Lineage monoclonal antibody mutations N501Y National neutralization assays novel lineage REGN-COV2 cocktail SARS-CoV-2 lineage SARS-CoV-2 variant sequence spike gene Spread spring therapeutic variants of concern [DOI] 10.1038/s41467-022-28766-y PMC 바로가기 [Article Type] Article
Molecular epidemiology of the SARS-CoV-2 variant Omicron BA.2 sub-lineage in Denmark, 29 November 2021 to 2 January 2022덴마크에서 SARS-CoV-2 변종 Omicron BA.2 하위 계통의 분자 역학, 2021년 11월 29일부터 2022년 1월 2일까지Article Published on 2022-03-012022-09-11 Journal: Eurosurveillance [Category] MERS, SARS, 변종, 유전자 메커니즘, 진단, [키워드] analysed Analysis BA.1 BA.2 Capital Capital Region Christma Cluster COVID-19 Denmark dominant epidemiological Epidemiology individual Lineage omicron phylogenetic analyses Region replaced REPLACED BY SARS-CoV-2 SARS-CoV-2 variant the SARS-CoV-2 Transmission variant variant of concern West [DOI] 10.2807/1560-7917.ES.2022.27.10.2200181 PMC 바로가기 [Article Type] Article