Rapid Antibody-Based COVID-19 Mass Surveillance: Relevance, Challenges, and Prospects in a Pandemic and Post-Pandemic WorldReview Published on 2020-10-212022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] Accuracy active infections acute respiratory syndrome antibody antibody-based testing approach Asymptomatic Blood clinics Community contagious coronavirus Coronavirus-2 COVID-19 detect Diagnosis disease early diagnosis effective Efficacy epidemiological Factor hidden host immune system Immunoglobulin immunoglobulins Increased Infection Laboratory management mass MERS Middle East Non-invasive nucleic acid outbreak pandemic POCT Point of Care Test population surveillance produced provided Rapid Rapid test Relevance repeated researcher SARS-CoV-2 Screening specificity Spread Surveillance syndrome the disease viral disease [DOI] 10.3390/jcm9103372 PMC 바로가기 [Article Type] Review
Higher Sensitivity Provided by the Combination of Two Lateral Flow Immunoassay Tests for the Detection of COVID-19 ImmunoglobulinsCOVID-19 면역글로불린 검출을 위한 두 가지 측면 유동 면역분석 검사의 조합으로 제공되는 더 높은 감도Cellular and Infection Microbiology Published on 2020-10-212022-09-11 Journal: Frontiers in Cellular and Infection Microbiology [Category] MERS, SARS, 진단, 치료기술, [키워드] affected affecting Combination COVID-19 Cross reactivity death detection diagnostics disease exceeded Flow Healgen Health Organization IgG IgM IgM and IgG IgM/IgG immunochromatographic assay immunoglobulins Infection Lateral lateral flow lateral flow immunoassay limit of detection manifested molecular pandemic parameter Patient presenting reported respiratory respiratory symptom respiratory symptoms RT-PCR SARS-CoV-2 SARS-CoV-2 IgM sensitivities sensitivity serology serology testing significantly specificity subject Test The United States United States variations WHO World Health Organization Wuhan Wuhan, China [DOI] 10.3389/fcimb.2020.00479 PMC 바로가기 [Article Type] Cellular and Infection Microbiology
Sex, age, and hospitalization drive antibody responses in a COVID-19 convalescent plasma donor populationResearch Article Published on 2020-10-192023-07-01 Journal: The Journal of Clinical Investigation [Category] SARS, [키워드] COVID-19 immunoglobulins [DOI] 10.1172/JCI142004 PMC 바로가기 [Article Type] Research Article
High levels of SARS-CoV-2–specific T cells with restricted functionality in severe courses of COVID-19Clinical Medicine Published on 2020-10-152022-10-30 Journal: JCI Insight [Category] COVID-19, MERS, SARS, [키워드] Activation acute respiratory syndrome affecting alteration analyzed Anergy antibody CD4 CD8 Cellular immune response Characteristics characterized controls convalescent individuals Convalescent patients coronavirus coronavirus disease correlated Course COVID-19 COVID-19 patient cytokine disease severity ELISA expression functional IFN-γ IgA IgA antibody IgG IgG levels IL-2 Immunity immunoglobulins immunopathology lung lymphocyte lymphocyte subpopulation lymphopenia marker mounted Patient patient group peptide pool phenotypical plasmablast proliferation quantified Rolf SARS-CoV-2 SARS-CoV-2 specific T-cell severe disease Severity of disease significantly higher state subpopulations supported T cell T cells TNF-α uninfected uninfected control university viral replication [DOI] 10.1172/jci.insight.142167 PMC 바로가기 [Article Type] Clinical Medicine
A simple protein-based surrogate neutralization assay for SARS-CoV-2Research Article Published on 2020-10-022022-10-30 Journal: JCI Insight [Category] COVID-19, MERS, [키워드] ACE2 acute respiratory syndrome Adaptive immunity angiotensin-converting enzyme 2 antibody Antigen assays characterized Clinical outcome Cohort Convalescent patients Convalescent plasma therapy coronavirus detect ELISA humoral immune response immune correlate immunoglobulins Infection Infectious disease Interaction live SARS-CoV-2 MOST neutralization Neutralization assay neutralizing antibody Patient performed plaque reduction neutralization platform PRNT pseudotyped public health RBD receptor Receptor binding domain Safe SARS-CoV-2 SARS-COV-2 infection serum and plasma Spike protein Support the patient the RBD the SARS-CoV-2 treatment approaches Vaccination strategies virus while [DOI] 10.1172/jci.insight.142362 PMC 바로가기 [Article Type] Research Article
Anti-Rheumatic Drugs for the Fight Against the Novel Coronavirus Infection (SARSCoV-2): What is the Evidence?Review Published on 2020-09-212022-10-31 Journal: Mediterranean Journal of Rheumatology [Category] COVID-19, [키워드] “cytokine storm” ACE2 receptor addition Against anti-cytokine antimalarial Asymptomatic cause clinical trial Colchicine Course COVID-19 COVID-19 infection COVID-19 symptoms current cytokine Cytokine storm Cytokines death develop drug dysregulated elderly expressed high risk Hydroxychloroquine IL-1 IL-6 immune system immunoglobulins intensive care intravenous male medical condition novel occur Other Patient patients plethora positive-sense single-stranded RNA pro-inflammatory cytokine producing Protein pulse reduce respiratory cells SARS-CoV-2 selected severe complications severely infected patient shown smoker spike Spike protein therapy Tocilizumab Treatment ventilatory support virus [DOI] 10.31138/mjr.31.3.259 PMC 바로가기 [Article Type] Review
Immune-related factors associated with pneumonia in 127 children with coronavirus disease 2019 in Wuhan2019년 우한에서 코로나바이러스 질병에 걸린 어린이 127명의 폐렴과 관련된 면역 관련 요인Article Published on 2020-09-012022-09-12 Journal: Pediatric pulmonology [Category] Coronavirus, SARS, 진단, [키워드] 95% CI 95% confidence interval Analysis analyzed applied association blood biochemistry Care cause CD25 CD4 children children with COVID-19 coronavirus disease Coronavirus disease 2019 COVID-19 cytokine Cytokines Decreased enrolled Factor hypersensitive C-reactive protein IgA IL-10 Immunoglobulin immunoglobulin A immunoglobulins Inflammatory factor information Laboratory less Logistic regression Lymphocyte subsets marker mean value normal range Odds ratio parameter Pathogenesis Patient patients Pneumonia procalcitonin routine blood tests T lymphocyte were excluded with COVID-19 Wuhan [DOI] 10.1002/ppul.24907 PMC 바로가기 [Article Type] Article
First neonates with severe acute respiratory syndrome coronavirus 2 infection in Romania Three case reports6200 Published on 2020-08-142022-10-30 Journal: Medicine [Category] COVID-19, MERS, [키워드] acute respiratory syndrome age Antifungal treatment Case report Case series chest X-ray consecutive negative test coronavirus coronavirus disease COVID-19 develop diaper erythema discharged form had no immunoglobulins infected with COVID-19 Infection infiltration information lack Manifestations medium Mild Neonate Neonates Newborn nonspecific oral candidiasis pandemic parenchymal Patient Pediatric case pleura positive Prophylactic reported Romania SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome coronavirus 2 Spread susceptible symptomatic tested the disease the patient thrombocytopenia Topic visceral [DOI] 10.1097/MD.0000000000021284 PMC 바로가기 [Article Type] 6200
Early safety indicators of COVID-19 convalescent plasma in 5000 patientsArticle Published on 2020-08-102023-07-02 Journal: The Journal of Clinical Investigation [Category] SARS, [키워드] COVID-19 drug therapy immunoglobulins [DOI] 10.1172/JCI140200 PMC 바로가기
Systemic immunosuppression in times of COVID-19: Do we need to rethink our standards?COVID-19 시대의 전신 면역 억제: 우리의 기준을 재고해야 합니까?Review Published on 2020-08-012022-09-11 Journal: Journal der Deutschen Dermatologischen Gesellschaf [Category] 치료제, [키워드] antiviral immunity Autoimmune disease Autoimmune diseases Cardiopulmonary Care Chloroquine Course COVID-19 disease doxycycline doxycycline) Effect effective therapy higher risk Hydroxychloroquine immunoglobulins immunomodulating Immunosuppression immunosuppressive immunosuppressive therapy indication inhibitors intrinsic metabolic conditions Older pandemic Patient pause principle reduction rituximab SARS-CoV-2 SARS-CoV-2 pandemic suppress systemic the SARS-CoV-2 therapy vaccination [DOI] 10.1111/ddg.14194 PMC 바로가기 [Article Type] Review