Performance of EasyBreath Decathlon Snorkeling mask for delivering continuous positive airway pressureArticle Published on 2021-03-102022-10-29 Journal: Scientific Reports [Category] Coronavirus, SARS, [키워드] 10 healthy volunteer Combination COVID-19 pandemic CPAP Decathlon Diaphragm electrical greater Health care hospital maintain noninvasive respiratory performance positive airway pressure Respiratory distress syndrome significantly increased Snorkeling Support ventilator were measured [DOI] 10.1038/s41598-021-85093-w PMC 바로가기 [Article Type] Article
IL-6 and other biomarkers as predictors of severity in COVID-19COVID-19의 심각성을 예측하는 IL-6 및 기타 바이오마커Research Article Published on 2021-03-042022-09-10 Journal: Annals of Medicine [Category] 바이오마커, [키워드] acute respiratory distress acute respiratory distress syndrome Admission admitted to ICU Biomarker Biomarkers C-reactive protein Coagulation COVID-19 CRP cytokine Cytokine release syndrome Cytokine storm D-dimer end organ end organ damage ferritin group hospital hospitalized patient hospitalized patients ICU identify IL-6 Inflammation inflammatory phase interferon interleukin interleukin-6 Lymphocytes marker mechanism median No statistical differences objective on admission organ damage Patient predictor procalcitonin recorded respiratory distress Respiratory distress syndrome Result Serum level severe COVID-19 severity Severity of disease significantly higher statistical difference statistical differences suggested syndrome the strongest Tocilizumab triggering with COVID-19 [DOI] 10.1080/07853890.2020.1840621 PMC 바로가기 [Article Type] Research Article
Increased kynurenine-to-tryptophan ratio in the serum of patients infected with SARS-CoV2: An observational cohort studySARS-CoV2에 감염된 환자의 혈청에서 키누레닌 대 트립토판 비율 증가: 관찰 코호트 연구Observational Study Published on 2021-03-012022-09-11 Journal: Biochimica et biophysica acta. Molecular basis of [Category] MERS, SARS, 바이오마커, 임상, [키워드] activated Activation acute respiratory distress acute respiratory distress syndrome addition age balance Biomarker Cytokines death dysregulation Emergency emergency room examined hallmark healthy controls healthy subject healthy subjects highest HPLC immune immune dysregulation immune reactivity immune tolerance increase in Increased Infection Inflammation inflammatory state intensive care intensive care unit Italy Kynurenine Kynurenine pathway Kynurenine:Tryptophan ratio lymphopenia males mechanism metabolism Observational cohort study Patient patients positive patients positively correlated pro-inflammatory cytokine pro-inflammatory cytokines reactivity recruited reflect respiratory distress Respiratory distress syndrome Rome room SARS-CoV2 SARS-CoV2 infection serum Serum level severe lymphopenia severity Severity of infection Severity of infection. significant difference Stage syndrome therapeutic intervention Tolerance Tryptophan were assessed [DOI] 10.1016/j.bbadis.2020.166042 PMC 바로가기 [Article Type] Observational Study
The Risk of Spread of Infection During Craniotomy/Craniostomy on Patients with Active Coronavirus Disease 2019 (COVID-19) Infection: Myth or Fact?활성 코로나바이러스 질환 2019(COVID-19) 감염 환자의 개두술/개두술 중 감염 확산 위험: 신화 또는 사실?Article Published on 2021-03-012022-09-11 Journal: World neurosurgery [Category] SARS, 치료기술, [키워드] acute respiratory distress acute respiratory distress syndrome aerosol aerosol-generating procedure aerosol-generating procedures Aerosols bone Bone dust Cell Chain Reaction Cohort collected coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 infection COVID-19-related symptoms craniotomy Craniotomy. determine disease transmission dust evaluate health worker moderate mucosal myth nasopharyngeal Operating room paranasal Paranasal sinuses Patient performed polymerase chain polymerase chain reaction positive required respiratory distress Respiratory distress syndrome reverse transcription reverse transcription polymerase chain reaction risk Spread surgery surgical Symptom syndrome tested the disease unlikely Viral load virus [DOI] 10.1016/j.wneu.2020.12.040 PMC 바로가기 [Article Type] Article
Immune reactivity during COVID-19: Implications for treatmentCOVID-19 동안의 면역 반응성: 치료에 대한 시사점Review Published on 2021-03-012022-09-11 Journal: Immunology letters [Category] MERS, SARS, 바이오마커, 신약개발, 임상, 진단, 치료법, [키워드] acute respiratory distress acute respiratory distress syndrome affected Antigen appear ARDS best C reactive protein cardiovascular comorbidities cardiovascular comorbidity CD19 cells characterized clinical Clinical symptoms clinical trial clinical trials Coagulopathy contribute convalescent plasma Corticosteroids cough COVID-19 COVID-19 patients Critical CRP Cytokine storm D-dimer disease drug therapy dysregulation Eosinopenia expression fatigue Fever focus helping hematological hematological parameter HLA-DR Host immune response human leukocyte antigen IL-6 IL-6 receptor immune immune dysregulation immune reactivity immune response Immunoglobulin immunological immunological reactivity immunosenescence Immunotherapy in-hospital mortality include Inflammatory response Intravenous immunoglobulin intubation IVIG Laboratory laboratory findings laboratory indexes. lead leukocyte Lymphocytes lymphopenia Macrophage macrophage activation syndrome Mild natural killer occur pathogenic mechanism pathogenic mechanisms Patient patients with COVID-19 predict procalcitonin prognostic biomarker Prognostic biomarkers Prognostic value receptor antagonist reduced reduction respiratory distress Respiratory distress syndrome SARS-CoV-2 severe COVID-19 severity severity of illness symptoms of COVID-19 syndrome T cell T cell response target Therapeutic strategies therapy Tocilizumab trajectory Treatment [DOI] 10.1016/j.imlet.2021.01.001 PMC 바로가기 [Article Type] Review
Angiotensin-Converting-Enzyme 2 and Renin-Angiotensin System Inhibitors in COVID-19: An UpdateCOVID-19의 안지오텐신-전환-효소 2 및 레닌-안지오텐신 시스템 억제제: 업데이트Review Published on 2021-03-012022-09-11 Journal: High blood pressure & cardiovascular prevention : [Category] SARS, 치료제, [키워드] ACE inhibitor ACE inhibitors ACE2 ACE2 gene ACEi acute respiratory distress syndrome affected aldosterone Analysis ANG-II angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 ARBs ARDS association benefit blocker candidate vaccine caused clinical study clinical trials Comorbidity component Corona COVID-19 COVID-19 infection decreased expression diabete diabetes Diabetes Mellitus dysfunction enzyme facilitate fatality high risk highlight host cell Human immune system hypertension individual inhibitor Interaction medication medications mortality rate outbreak patients with diabete progression RAS RAS inhibitors receptor Receptor Blockers receptors recombinant ACE2 regulate Renin renin-angiotensin-aldosterone system reported respiratory respiratory distress Respiratory distress syndrome SARS-CoV-2 SARS-CoV2 severe disease System target Therapies Treatment treatment of COVID-19 treatment strategy Virus Disease virus entry [DOI] 10.1007/s40292-021-00439-9 PMC 바로가기 [Article Type] Review
At the Crossroads: COVID-19 and Immune-Checkpoint Blockade for Cancer갈림길에서: COVID-19와 암에 대한 면역 관문 차단Article Published on 2021-03-012022-09-11 Journal: Cancer immunology research [Category] 바이오마커, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antiviral immune response antiviral immune responses blockade Cancer Characteristics clinical trials Complication complications of COVID-19 coronavirus coronavirus disease Coronavirus disease 2019 Course COVID-19 COVID-19 infection COVID-19 pandemic COVID-19 vaccination death decrease detrimental disease course Effect Evidence expression heterogeneity immune responses immunomodulatory effect immunomodulatory effects infections Inflammatory inflammatory complications Inflammatory response Inflammatory responses interferon interferon signaling leads Ligand MOST pathway Patient patients Patients with cancer PD-L1 PD1 PROTECT provided receiving receptor respiratory respiratory distress Respiratory distress syndrome RNA virus SARS-CoV-2 severe acute respiratory syndrome Coronavirus Severe case severe cases Severe respiratory distress Support syndrome the disease therapy Viral viral infection virus infections worsening [DOI] 10.1158/2326-6066.CIR-21-0008 PMC 바로가기 [Article Type] Article
Ethnic and age-specific acute lung injury/acute respiratory distress syndrome risk associated with angiotensin-converting enzyme insertion/deletion polymorphisms, implications for COVID-19: A meta-analysis인종 및 연령별 급성 폐 손상/급성 호흡 곤란 증후군 위험, 안지오텐신 전환 효소 삽입/제거 다형성, COVID-19에 대한 시사점: 메타 분석Meta-Analysis Published on 2021-03-012022-09-11 Journal: Infection, genetics and evolution : journal of mol [Category] SARS, 변종, 유전자 메커니즘, [키워드] 95% CI 95% confidence interval ACE acute lung injury acute respiratory distress syndrome addressed Adults ALI/ARDS allele analyses Analysis angiotensin Angiotensin-converting enzyme ARDS ARDS patient ARDS patients article Asian Asians assessment association associations Bonferroni correction Caucasian Caucasians children CIs Comparisons conducted coronavirus disease Coronavirus disease 2019 covariate covariates COVID-19 distress dominant Ethnicity examined genetic model Genotype healthy control healthy controls heterogeneity I/D I/D polymorphism implication include indicated insertion/deletion life lung Lung injury Meta-analysis meta-regression Mortality Odds ratios outcome outlier pandemic Patient patients with COVID-19 polymorphism Polymorphisms Regression reported respiratory distress Respiratory distress syndrome risk robust robustness Significant Statistical power statistically Subgroup analyses subgroup analysis syndrome therapy Topic Treatment was performed [DOI] 10.1016/j.meegid.2020.104682 PMC 바로가기 [Article Type] Meta-Analysis
SARS-CoV-2 and superimposed infection by trichomonadsComment Published on 2021-03-012023-06-19 Journal: The Journal of Infection [Category] Fulltext, SARS, [키워드] COVID-19 pneumocystis pneumonia Respiratory distress syndrome SARS-CoV-2 Trichomonas infections. [DOI] 10.1016/j.jinf.2020.11.038 PMC 바로가기 [Article Type] Comment
Pharmacological treatment of COVID-19: Narrative review of the Working Group in Infectious Diseases and Sepsis (GTEIS) and the Working Groups in Transfusions and Blood Products (GTTH)COVID-19의 약리학적 치료: 감염성 질환 및 패혈증 작업 그룹(GTEIS) 및 수혈 및 혈액 제제 작업 그룹(GTTH)에 대한 설명 검토Review Published on 2021-03-012022-09-11 Journal: Medicina intensiva [Category] SARS, 진단, 치료기술, 치료제, [키워드] acute respiratory distress acute respiratory distress syndrome Acute respiratory failure adopted applied ARDS ARDS-CoV-2 Care changes in China clinical trial clinical trials conditions coronavirus coronavirus disease Coronavirus disease-19 COVID-19 COVID-19 disease defined Evidence group Health Organization help ICU Infectious disease intensive care unit lack life-threatening management management guidelines many case many cases Mild narrative offer outbreak pandemic Patient product protocol protocols provide recent reported respiratory distress Respiratory distress syndrome Respiratory failure SARS-CoV-2 SARS-CoV-2 virus scientific evidence seeking Spread syndrome the SARS-CoV-2 virus therapy transfusion Tratamiento Treatment treatment guidelines UCI. WHO working World Health Organization [DOI] 10.1016/j.medin.2020.06.017 PMC 바로가기 [Article Type] Review