Comparison of the clinical performance and usefulness of five SARS-CoV-2 antibody tests5가지 SARS-CoV-2 항체 검사의 임상 성능 및 유용성 비교Comparative Study Published on 2021-02-082022-09-10 Journal: PLoS ONE [Category] MERS, 진단, 치료기술, [키워드] both groups comparable COVID-19 antibody COVID-19 patients cut-off Elecsy Elecsys epidemiological studies examined FIVE group immunochromatography in both groups Infection Interpretation Japanese Roche SARS-CoV-2 antibody SARS-CoV-2 antibody test serum sample serum samples severe cases severity specificity two group two groups [DOI] 10.1371/journal.pone.0246536 PMC 바로가기 [Article Type] Comparative Study
Sensitivity of anti-SARS-CoV-2 serological assays in a high-prevalence setting유병률이 높은 환경에서 항 SARS-CoV-2 혈청학적 분석의 민감도Comparative Study Published on 2021-02-032022-09-10 Journal: European Journal of Clinical Microbiology & Infect [Category] MERS, SARS, 진단, 치료기술, [키워드] Abbott anti-SARS-CoV-2 anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 antibody Contact COVID-19 DiaSorin discrepancy Euroimmun house identify immunofluorescence Immunofluorescence test individuals neutralization neutralization test neutralization titer Neutralizing antibodies performed positive test result power predict Roche SARS-CoV-2 sensitivity Serological assay serological assays serological test Serological tests serology seropositive seropositive individual Seroprevalence spreader supplementary material test results tested [DOI] 10.1007/s10096-021-04169-7 PMC 바로가기 [Article Type] Comparative Study
Repurposing of renin inhibitors as SARS-COV-2 main protease inhibitors: A computational studyResearch article Published on 2021-02-012022-10-05 Journal: Virology [Category] SARS, 신약개발, [키워드] ACE2 addition catalytic site Compound computational studies Computational study COVID-19 COVID-19 pandemic Cys145 docking drug enzyme exhibited His41 inhibitor inhibitors management molecular dynamics molecular interaction pharmacophore protease Protease inhibitor protease inhibitors receptor Regulation released Remikiren Renin repurposing responsible Roche SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 main protease suggested Treatment was performed [DOI] 10.1016/j.virol.2020.12.008 [Article Type] Research article
Clinical evaluation of commercial automated SARS-CoV-2 immunoassays상용 자동화된 SARS-CoV-2 면역분석의 임상 평가Article Published on 2021-02-012022-09-11 Journal: International Journal of Infectious Diseases [Category] MERS, SARS, 진단, 치료기술, [키워드] antibody Antibody detection assays automated Automated SARS-CoV-2 antibody detection clinical Control COVID-19 infection diagnostic diagnostic sensitivities Diagnostic specificities diagnostic specificity DiaSorin epitope Euroimmun excluded facilitate four groups High throughpu testing IgA IgG IgM IgM/IgG immunoassay Infection involved laboratory-confirmed lack lead Longitudional monitoring of antibody development negative control negative controls number of samples Numerous pandemic control Patient performed positive qRT-PCR released reproducibility retrospective Roche SARS-CoV-2 SARS-CoV-2 antibody sensitivity sera Seroconversion serological serological assays serological result Serpprevalence. significantly SNIBE specificity the disease validation [DOI] 10.1016/j.ijid.2020.12.003 PMC 바로가기 [Article Type] Article
Performance of two rapid point of care SARS-COV-2 antibody assays against laboratory-based automated chemiluminescent immunoassays for SARS-COV-2 IG-G, IG-M and total antibodiesArticle Published on 2021-01-192022-10-29 Journal: Practical Laboratory Medicine [Category] COVID-19, [키워드] 95% CI Abbott analysed antibodies antibody assay Antibody assays Antigen Architect Assay evaluation automated chemiluminescent immunoassay CLIA Concordance condition Control COVID-19 cross-reactivity dsDNA evaluated IgG IgM IMPROVE information Like NPV PanBio performance POCT point of care point-of-care test point-of-care testing POS positive positive RT-PCR PPV Predictive Prevalence Rapid recruited Result Roche RT-PCR SARS-CoV-2 SARS-CoV-2 antibody sensitivity sera specificity subject total antibody utility Viral hepatitis were assessed were used [DOI] 10.1016/j.plabm.2021.e00201 PMC 바로가기 [Article Type] Article
Head-to-Head Comparison of Rapid and Automated Antigen Detection Tests for the Diagnosis of SARS-CoV-2 InfectionArticle Published on 2021-01-132022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] aligned antigen testing asymptomatic subject automated automated assay CDC contagious contagiousness COVID-19 detection diagnosis of SARS-CoV-2 faster FIVE Healgen identify Infection less manual assay nasopharyngeal sample PanBio patients ranged Rapid Roche RT-PCR RT-PCR positive patient SARS-CoV-2 SARS-CoV-2 RNA sensitivity specificity symptomatic patient Test tested Viral load viral loads [DOI] 10.3390/jcm10020265 PMC 바로가기 [Article Type] Article
Seroprevalence of SARS-CoV-2-specific antibodies in the town of Ariano Irpino (Avellino, Campania, Italy): a population-based studyResearch Article Published on 2021-01-122022-10-31 Journal: Future Science OA [Category] COVID-19, [키워드] Abstract Analysis anti-SARS-CoV-2 anti-SARS-CoV-2 antibody antibody Ariano Irpino ASL asymptomatic individual Asymptomatic individuals Blood blood draw Campania conducted COVID-19 COVID-19 pandemic Department Elecsy Epidemiology females individual Infection Italian Italy males Naples organized pediatric cohort positive positive individual Prevalence proportion Public Public health intervention responsible Roche RT-PCR SARS Coronavirus SARS-CoV-2 SARS-CoV-2-specific antibody screening strategy serological seropositive Seroprevalence service Spread tested university virus [DOI] 10.2144/fsoa-2020-0203 PMC 바로가기 [Article Type] Research Article
Diagnostic Accuracy of Electro-Chemiluminescence Immunoassay Anti-SARS-CoV-2 Serological TestAllergy/Immunology Published on 2021-01-092022-10-31 Journal: Cureus [Category] COVID-19, [키워드] Accuracy age Analysis analyzed anti-SARS-CoV-2 anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 antibody Asymptomatic automated characteristic Complication COVID 19 COVID-19 determine diagnostic Diagnostic accuracy disease females FIVE Gender immunoassay Informed consent likelihood ratio male Most patient Negative predictive value NPV over Patient PCR PCR positive polymerase chain positive Positive predictive value PPV questionnaire ROC Roche RT-PCR Sample SARS-COV-2 infection selected sensitivity serological test specificity Symptoms Test tested the patient was obtained [DOI] 10.7759/cureus.12588 PMC 바로가기 [Article Type] Allergy/Immunology
Limits and Opportunities of SARS-CoV-2 Antigen Rapid Tests: An Experienced-Based PerspectiveCommunication Published on 2021-01-052022-10-28 Journal: Pathogens [Category] COVID-19, [키워드] Abbott addition analyzed Antigen benefit bronchoalveolar clinical setting correlation COVID-19 diagnostic eight evaluated gold standard Lateral flow test material opportunity PanBio PCR ranged Rapid Rapid antigen tests RapiGEN rising Roche SARS-CoV-2 SARS-COV-2 infection sensitivity specificity tested the SARS-CoV-2 [DOI] 10.3390/pathogens10010038 PMC 바로가기 [Article Type] Communication
Performance characteristics of five immunoassays for SARS-CoV-2: a head-to-head benchmark comparisonSARS-CoV-2에 대한 5가지 면역분석의 성능 특성: 일대일 벤치마크 비교Comparative Study Published on 2020-12-012022-09-06 Journal: The Lancet. Infectious Diseases [Category] Communicable Disease, MERS, SARS, 진단, [키워드] (Abbott 384-well ELISA 95% CI Abbott acute respiratory syndrome acute respiratory syndrome coronavirus Basel benchmark study benefit best blood sample Blood samples can be used caused Characteristics Chicago collected coronavirus DiaSorin Effects Elecsy Elecsys finding FIVE funding Germany global pandemic head head-to-head assessment Health IgG immunoassay individual Italy laboratory-confirmed SARS-CoV-2 infection LIAISON Metrics Munich novel Oxford Oxford immunoassay Patient performance public health Public Health England receiver operating characteristic resource respiratory risk Risk assessment ROC Roche S1/S2 SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 IgG SARS-COV-2 infection sensitivity Sensitivity and specificity Serological testing serology severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Siemen Siemens specificity Surveillance Switzerland symptom onset Testing threshold thresholds Total USA were used [DOI] 10.1016/S1473-3099(20)30634-4 PMC 바로가기 [Article Type] Comparative Study