A handheld intelligent single-molecule binary bioelectronic system for fast and reliable immunometric point-of-care testing빠르고 안정적인 면역 측정 현장 검사를 위한 휴대용 지능형 단일 분자 이원 생체 전자 시스템Article Published on 2022-07-082022-09-11 Journal: Science Advances [Category] COVID19(2023년), SARS, 치료기술, [키워드] Accuracy Antigen antigenic artificial intelligence assays binary classification Blood cartridge detect diagnostic diagnostic sensitivity early diagnosis handling Immunoglobulin Immunoglobulin G lack limit Molecular tests Patient pilot clinical trial platform point-of-care Protein reliability Saliva SARS-CoV-2 virus sensitivity serum simplicity smart device specificity Swab The diagnostic sensitivity the SARS-CoV-2 virus [DOI] 10.1126/sciadv.abo0881 PMC 바로가기 [Article Type] Article
Detection of SARS-CoV-2 Specific Antibodies in Saliva Samples타액 샘플에서 SARS-CoV-2 특이적 항체 검출Article Published on 2022-07-082022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] analyzed conversion rates coronavirus coronavirus disease COVID-19 detection diagnose diagnosed with COVID-19 Diagnosis diagnostic diagnostic test different time point different time points early diagnosis enrolled Evidence Hospitalization IgA IgG and IgM IgG level IgM Immunoglobulin immunoglobulins limit Molecular assay molecular assays nasopharyngeal nasopharyngeal sampling Nasopharyngeal swab nasopharyngeal swabs nucleic acid nucleic acids Patient positive rate positive rates recent Saliva saliva IgA. Sample SARS-CoV-2 serum serum samples Shenzhen Specific specimen Viral viral nucleic acid viral nucleic acid detection viral nucleic acids were measured [DOI] 10.3389/fimmu.2022.880154 PMC 바로가기 [Article Type] Article
Nasopharyngeal swabs vs. saliva sampling for SARS-CoV-2 detection: A cross-sectional survey of acceptability for caregivers and children after experiencing both methodsSARS-CoV-2 검출을 위한 비인두 면봉 대 타액 샘플링: 두 가지 방법을 모두 경험한 후 간병인과 어린이의 수용 가능성에 대한 횡단면 조사Article Published on 2022-07-082022-09-11 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 치료기술, [키워드] 5-point Likert scale acceptability acceptance Accuracy Administered children Community Complete Consent COVID-19 testing cross-sectional survey described face Factor hypothetical Local Nasopharyngeal swab nasopharyngeal swabbing nasopharyngeal swabs Pain participant Participation preference Saliva sampling SARS-CoV-2 SARS-CoV-2 testing Swab understanding was measured Youth [DOI] 10.1371/journal.pone.0270929 PMC 바로가기 [Article Type] Article
Performance evaluation of a non-invasive one-step multiplex RT-qPCR assay for detection of SARS-CoV-2 direct from saliva타액에서 직접 SARS-CoV-2 검출을 위한 비침습적 원스텝 멀티플렉스 RT-qPCR 분석의 성능 평가Article Published on 2022-07-072022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 변종, 진단, 치료기술, [키워드] accreditation administer approach bypasse bypasses Chain Reaction clinical settings Compliance Concordance criteria demonstrated diagnostic diagnostic testing evaluated followed by helping increased risk invasive medium multiplex RT-qPCR nasopharyngeal specimen Non-invasive overcome Patient PCR performance performed polymerase chain reaction protocol qPCR assay quantitative PCR reducing Regulatory resulting reverse transcription RNA extraction robust RT-qPCR Saliva saliva specimens sample collection SARS-CoV-2 SARS-CoV-2 detection sensitivity service Swab swabbing swabs Testing United Kingdom university [DOI] 10.1038/s41598-022-15616-6 PMC 바로가기 [Article Type] Article
Decrease in Angiotensin-Converting Enzyme activity but not concentration in plasma/lungs in COVID-19 patients offers clues for diagnosis/treatmentResearch article Published on 2022-07-062022-10-05 Journal: Molecular Therapy [Category] 바이오마커, 변종, 임상, 치료기술, 치료법, [키워드] ACE2 activity/concentration biomarker in plasma/saliva soluble Angiotensin-Converting Enzyme 2 ACE2 acute respiratory syndrome age angiotensin-converting-enzyme Autopsy Biomarker clinical observation Concentration condition Control convalescent Corona virus coronavirus disease Coronavirus-2 COVID-19 COVID-19 disease COVID-19 patient disease disease severity dysregulation evaluate evaluated Hospitalization hospitalized COVID-19 patient human cell infect inverse correlation lung mACE2 marker membrane nadir no difference Non-COVID-19 offer Patient patients plasma Plasma marker plasmas quantitative test quarantine RAS pathway receptor reduced renin-angiotensin system restored sACE2 Saliva saliva marker SARS-CoV-2 SARS-CoV-2 diagnosis/treatment soluble ACE2 statistically therapeutic target tissue treat variations volunteers [DOI] 10.1016/j.omtm.2022.07.003 [Article Type] Research article
Pathogenic Mechanism and Multi-omics Analysis of Oral Manifestations in COVID-19COVID-19의 구강 증상의 병원성 메커니즘 및 다중 오믹스 분석Review Published on 2022-07-042022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 치료기술, [키워드] acute respiratory distress acute respiratory distress syndrome acute respiratory syndrome acute respiratory syndrome coronavirus Analysis bind caused clinical manifestation clinical manifestations coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patients cytokine Cytokines decrease droplets dysfunction dysregulation Factors Gustatory Host host cell host cells human ACE2 receptor immune immune cells immune dysregulation immune response Immunological analyses immunological analysis include infect Inflammation manifestation mount multi Multi-omics multiple organ failure Numerous oral oral cavity pathogen pathogenic phenotype reported respiratory distress respiratory infectious disease S protein Saliva SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 particle SARS-CoV-2 particles severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severe COVID-19 Spread structural protein structural proteins syndrome the S protein Trigger virus Xerostomia [DOI] 10.3389/fimmu.2022.879792 PMC 바로가기 [Article Type] Review
High Expression Level of α2-3-Linked Sialic Acids on Salivary Glycoproteins of Breastfeeding Women May Help to Protect Them from Avian Influenza Virus InfectionArticle Published on 2022-07-032023-05-31 Journal: Molecules [Category] 신종인플루엔자, 조류인플루엔자, [키워드] avian influenza virus (AIV) breastfeeding women glycoprotein Saliva sialic acids (Sia). [DOI] 10.3390/molecules27134285 PMC 바로가기
Screening and vaccination against COVID-19 to minimise school closure: a modelling study휴교 최소화를 위한 코로나19 검사 및 예방접종: 모델링 연구Article Published on 2022-07-012022-09-11 Journal: The Lancet. Infectious Diseases [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI addition agent Alpha Alpha variant Analysis B.1.1.7 B.1.617.2 benefit children circulating Community conditions Contact contagious Cost-benefit analysis Coverage COVID-19 pandemic delta variant effective Europe evaluate framework France Horizon Innovation Insufficient Intervention Lateral flow test Lateral flow tests maintain median PCR PCR tests performed pilot screening Prevalence primary school protocol protocols reactive reduce Regular reproductive risk Safe Saliva saliva samples SARS-CoV-2 SARS-CoV-2 transmission School Schools Screening secondary school Spread Surveillance Transmissibility transmissible variant vaccination vaccination against COVID-19 variant was recorded [DOI] 10.1016/S1473-3099(22)00138-4 PMC 바로가기 [Article Type] Article
Repetitive saliva-based mass screening as a tool for controlling SARS-CoV-2 transmission in nursing homes요양원에서 SARS-CoV-2 전염을 통제하기 위한 도구로서의 반복적인 타액 기반 대량 스크리닝Article Published on 2022-07-012022-09-11 Journal: Transboundary and emerging diseases [Category] COVID19(2023년), SARS, 치료기술, [키워드] absence activities addition affected Asymptomatic case Asymptomatic cases Belgium chain Cohort COVID-19 COVID-19 pandemic death decrease demonstrated detect Diagenode disease transmission disrupting Efficacy feasibility followed by incidence Inconclusive majority not affect Nursing nursing home participated pooling positive Prevalence RT-qPCR Saliva saliva test SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 transmission sensitivity Significant significantly Subsequent infection subsequent infections Transmission Viral transmission Weekly worker [DOI] 10.1111/tbed.14280 PMC 바로가기 [Article Type] Article
Virology and immune dynamics reveal high household transmission of ancestral SARS-CoV-2 strain바이러스 및 면역 역학은 조상 SARS-CoV-2 균주의 높은 가정 전염을 나타냅니다Article Published on 2022-07-012022-09-11 Journal: Pediatric allergy and immunology : official public [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료법, [키워드] acute phase Adults age antibodies Antibody Response Antibody responses attack rate Blood characterized children coronavirus COVID-19 Ct values determine family members feature generate highlight household household transmission Households immune immunological immunology index case Infection IQR Isolation key factor Local measure Melbourne Melbourne, Australia mucosal nasopharyngeal Nasopharyngeal swab Neutralizing antibodies Novel coronavirus NPs nucleocapsid protein participant PCR PCR positivity PCR testing plasma antibody positive provide respiratory respiratory sample Respiratory samples response Saliva SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 antigen SARS-CoV-2 antigens SARS-COV-2 infection SARS-CoV-2 strain SARS-CoV-2 variants SARS-CoV-2 viral load SARS-CoV-2-specific antibodies SARS-CoV-2, household transmission secondary attack rate secondary transmission specific antibodies spike Stool tested Transmission transmission of SARS-CoV-2 Viral Virology [DOI] 10.1111/pai.13824 PMC 바로가기 [Article Type] Article