Circulatory Exosomes from COVID-19 Patients Trigger NLRP3 Inflammasome in Endothelial Cells
COVID-19 환자의 순환 엑소좀은 내피 세포에서 NLRP3 인플라마좀을 유발합니다
Article
[키워드] Activation of caspase-1
acute respiratory syndrome
acute respiratory syndrome coronavirus
augmentation
blood flow
cargo
caspase
caspase-1
Cell
Circulatory
Coagulation
Coagulopathy
combating
Control
coronavirus
coronavirus 2
COVID-19
Culture
culture medium
Cytokine storm
demonstrated
drug
endothelial
Endothelial cell
endothelial cells
ENhance
examined
Exosome
Exosomes
exposure to
extracellular vesicle
Extracellular vesicles
Health
health problem
healthy donors
help
highlight
IL-1β
Immunopathogenesis
induce
Infection
Inflammasome
Inflammation
Inflammatory response
inhibit
interleukin
interleukin-1β
investigator
liver
mechanism
medium
Mild
Mild disease
molecular
molecular mechanism
mRNA expression
Multiple organ damage
NLRP3
NLRP3 inflammasome
opens
organ
organ damage
Pathogenesis
Patient
plasma
predicted
Prevent
respiratory
resting
resulting
SARS-CoV-2
SARS-COV-2 infection
secretion
Severe acute respiratory syndrome
severe acute respiratory syndrome Coronavirus
severe acute respiratory syndrome coronavirus 2
severe COVID-19 patient
severe COVID-19 patients
significantly
the vaccine
Therapies
Trigger
Vaccine
Venous Thromboembolism
with mild disease
[DOI] 10.1128/mbio.00951-22 PMC 바로가기 [Article Type] Article
[DOI] 10.1128/mbio.00951-22 PMC 바로가기 [Article Type] Article