The Prognostic Value of Thrombocytopenia in COVID-19 Patients; a Systematic Review and Meta-AnalysisReview Article Published on 2020-09-192022-10-27 Journal: Archives of Academic Emergency Medicine [Category] COVID-19, [키워드] Abstract article Blood platelets Chi-square clinically COVID-19 COVID-19 patient COVID-19 severity decrease Decreased disease Diseases English Evidence heterogeneity information initial search library marker mean difference Medicine Meta-analysis Multiple Non-severe case outcome performed Platelet Platelets poor prognosis Probability Prognosis Prognostic value representing review SARS-CoV-2 screened searched selected Severe case severe cases severity significantly higher the disease thrombocytopenia value was tested were used PMC 바로가기 [Article Type] Review Article
Platelets and Their Role in the Pathogenesis of Cardiovascular Events in Patients With Community-Acquired Pneumonia혈소판과 지역사회 획득 폐렴 환자에서 심혈관 사건의 발병 기전에서의 역할Review Published on 2020-09-172024-07-30 Journal: Frontiers in immunology [Category] 폐렴구균 감염증, [키워드] anti-platelet agents Cardiovascular events community-acquired pneumonia high mobility group box 1 protein Platelets pneumococcus Pneumolysin thrombocytopenia [DOI] 10.3389/fimmu.2020.577303 PMC 바로가기 [Article Type] Review
A meta-analysis of potential biomarkers associated with severity of coronavirus disease 2019 (COVID-19)코로나바이러스 질병 2019(COVID-19)의 심각성과 관련된 잠재적 바이오마커의 메타 분석Review Published on 2020-08-312022-08-07 Journal: Biomarker Research [Category] Biochemistry, COVID-19, [키워드] (lymphocyte (procalcitonin 95%CI albuminemia association available data Bilirubin biochemical Biochemical parameters Biomarker Biomarkers Blood level Blood urea nitrogen C-reactive protein CK-MB coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 case Creatininemia CRP D-dimer effect sizes elevated eosinophil eosinophils Factor haematologic Haemoglobin help hematological higher risk identify Inflammatory interleukin interleukin-6 LDH lymphocyte Lymphocyte count Lymphocytes lymphopenia Meta-analysis Myoglobin nitrogen opposition P-value patients with COVID-19 Potential biomarker procalcitonin procalcitonin level Prognostic biomarkers prognostic risk stratification proportion Protein prothrombin Prothrombin time Random-effects meta-analysis Result retained searched severe cases severe COVID-19 Severe patient severe patients severity severity of COVID-19 significantly significantly lower significantly more SMD standardized mean difference thrombocyte Thrombocytes thrombocytopenia total bilirubin troponin troponin I urea was used Web γ-GT PMC 바로가기 [Article Type] Review
Compassionate use of JAK1/2 inhibitor ruxolitinib for severe COVID-19: a prospective observational study중증 COVID-19에 대한 JAK1/2 억제제 룩소리티닙의 동정적 사용: 전향적 관찰 연구Clinical Trial Published on 2020-08-192022-08-13 Journal: Leukemia [Category] MERS, SARS, 바이오마커, 신약개발, 임상, 치료제, [키워드] 95% confidence interval activated adverse event age Anemia anti-inflammatory properties clinical Clinical improvement Comorbidities Comorbidity compassionate-use compassionate-use protocol contribute Controlled clinical trial controlled clinical trials COVID-19 cumulative incidence cytokine defined discharge home distress Efficacy exposure time FiO2 high-flow oxygen support improvement Infectious diseases Inflammatory cytokine inflammatory cytokine profile inflammatory reaction inhibitor JAK1 JAK1/JAK2 inhibitor JAK2 less lymphocyte Lymphocyte subset median age median dose intensity not affected observational study Ordinal Scale overall survival oxygen oxygen saturation PaO2 paO2/fiO2 PaO2/FiO2 ratio Patient patients with COVID-19 prospective cohort prospective observational study pulmonary disease Pulmonary function pulmonary infiltrate pulmonary infiltrates respiratory distress ruxolitinib Safe severe COVID-19 severe pulmonary disease Therapeutics thrombocytopenia urinary tract infections [DOI] 10.1038/s41375-020-01018-y PMC 바로가기 [Article Type] Clinical Trial
The looming storm: Blood and cytokines in COVID-19Review Published on 2020-08-182023-06-14 Journal: Blood reviews [Category] MERS, SARS, [키워드] anticoagulation Coagulation COVID-19 Cytokine release syndrome thrombocytopenia thrombosis [DOI] 10.1016/j.blre.2020.100743 PMC 바로가기 [Article Type] Review
First neonates with severe acute respiratory syndrome coronavirus 2 infection in Romania Three case reports6200 Published on 2020-08-142022-10-30 Journal: Medicine [Category] COVID-19, MERS, [키워드] acute respiratory syndrome age Antifungal treatment Case report Case series chest X-ray consecutive negative test coronavirus coronavirus disease COVID-19 develop diaper erythema discharged form had no immunoglobulins infected with COVID-19 Infection infiltration information lack Manifestations medium Mild Neonate Neonates Newborn nonspecific oral candidiasis pandemic parenchymal Patient Pediatric case pleura positive Prophylactic reported Romania SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome coronavirus 2 Spread susceptible symptomatic tested the disease the patient thrombocytopenia Topic visceral [DOI] 10.1097/MD.0000000000021284 PMC 바로가기 [Article Type] 6200
SARS-CoV-2 induced thrombocytopenia as an important biomarker significantly correlated with abnormal coagulation function, increased intravascular blood clot risk and mortality in COVID-19 patientsResearch Published on 2020-07-172022-10-31 Journal: Experimental Hematology & Oncology [Category] COVID-19, [키워드] abnormal coagulation Admission alanine aminotransferase ALT analyzed Aspartate aminotransferase AST biochemical Biomarker Blood blood platelet cardiovascular event cascade Clinical prognosis Coagulation coagulation function Coronavirus disease 2019 coronavirus nucleic acid correlated COVID-19 COVID-19 patient COVID-19 patients death death case diagnosed diagnostic DIC disease disease severity enrolled function Hospitalization Huoshenshan Hospital IgM/IgG increased mortality increased risk INR International intravascular coagulation laboratory parameter lack Liver function Mortality non-severe group normalized occurred Other parameter Patient patients with COVID-19 Platelet positive predict Prothrombin time recovered patients Result risk SARS-CoV-2 severe disease severe group significantly subgroups survival tested thrombin thrombocytopenia Thromboembolism two groups used to evaluate viral disease while Wuhan [DOI] 10.1186/s40164-020-00172-4 PMC 바로가기 [Article Type] Research
Increased platelet distribution width and reduced IL-2 and IL-12 are associated with thrombocytopenia in Plasmodium vivax malaria혈소판 분포 폭 증가와 IL-2 및 IL-12 감소는 플라스모디움 비박스 말라리아에서 혈소판 감소증과 관련이 있다.Original Article Published on 2020-07-172024-08-11 Journal: WHO Chron [Category] 말라리아, [키워드] IL-1 beta IL-12p70 IL-2 Plasmodium vivax Platelet thrombocytopenia [DOI] 10.1590/0074-02760200080 PMC 바로가기 [Article Type] Original Article
Immune Thrombocytopenia in a Very Elderly Patient With Covid-19Medicine Published on 2020-07-102022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] acute respiratory syndrome Autoimmune autoimmune disorder bleeding characterized CMV coronavirus Corticosteroid Corticosteroids COVID-19 determine EBV elderly HCV hepatitis C virus HIV Human immunodeficiency virus Immune thrombocytopenia Infection Intravenous immunoglobulin Novel coronavirus infection Patient Platelet reported SARS-COV-2 infection severe adverse events therapeutic strategy thrombocytopenia Trigger triggered very old age virus [DOI] 10.3389/fmed.2020.00404 PMC 바로가기 [Article Type] Medicine
Clinical characteristics of 82 cases of death from COVID-19코로나19 사망자 82명의 임상적 특징Research Article Published on 2020-07-092022-08-13 Journal: PLoS ONE [Category] Biochemistry, COVID-19, MERS, SARS, [키워드] Admission age Alanine alanine aminotransferase aspartate Aspartate aminotransferase association C-reactive protein Cancer cardiac failure cause of death caused Cerebrovascular disease Characteristics clinical Clinical characteristics Clinical data Comorbidities Comorbidity COVID-19 cytokine cytokine release Cytokine release syndrome D-dimer Data collection death death case detected patients develop diabete diabetes diagnosed died disease electronic medical record followed by forms heart disease hemorrhage Hemorrhagic hemorrhagic damage hypertension ICU IL-6 initial symptom initial symptoms IQR laboratory-confirmed Lactate lactate dehydrogenase Local lymphocyte lymphopenia male mechanical ventilation support median age median time medical records MOST Most patient Most patients neutrophil Neutrophil-to-lymphocyte ratio neutrophilia Older on admission other organs oxygen Patient patients Pneumonia proportion remained renal renal damage renal failure respiratory Respiratory failure SARS-CoV-2 SARS-COV-2 infection Sepsis severe disease single center Spread systemic immune-inflammation index the median the patient thrombocytopenia treated virus Wuhan Wuhan local hospital’ Wuhan, China [DOI] 10.1371/journal.pone.0235458 PMC 바로가기 [Article Type] Research Article