Impact of the first wave of the COVID-19 pandemic on cancer registration and cancer care: a European surveyCOVID-19 대유행의 첫 번째 물결이 암 등록 및 암 치료에 미치는 영향: 유럽 조사Article Published on 2022-04-012022-09-11 Journal: The European Journal of Public Health [Category] COVID19(2023년), SARS, 치료기술, [키워드] activity Analysis Cancer cancer patient Cancer patients Care changes in Community coronavirus disease coronavirus disease COVID-19 country COVID-19 COVID-19 pandemic Diagnosis diagnostics Effect Europe European First wave hospital Impact in some Interpretation majority management medium network oncology operation pandemic Patient professionals questionnaire receiving reduction Region registries reported resource respondent response rate Treatment Variation virus [DOI] 10.1093/eurpub/ckab214 PMC 바로가기 [Article Type] Article
Serum zinc levels in pediatric patients with COVID-19Observational Study Published on 2022-04-012022-10-05 Journal: European journal of pediatrics [Category] COVID19(2023년), SARS, 임상, [키워드] Adults Analysis Antiviral effect association children conducted control group correlation COVID-19 Critical cut-off deficiency defined determine diagnosed with COVID-19 disease disease severity Factor growth Hospitalization hospitalizations Immunity incidence IQR living environment median median age neurologic participated Patient patients with COVID-19 Pediatric patient performed prospective observational study SARS-CoV-2 serum severity of COVID-19 Sex significantly higher significantly lower SPSS the median to define Variation window with COVID-19 Zinc [DOI] 10.1007/s00431-021-04348-w PMC 바로가기 [Article Type] Observational Study
Total antioxidant capacity as a marker of severity of COVID-19 infection: Possible prognostic and therapeutic clinical applicationCOVID-19 감염의 중증도 마커로서의 총 항산화 용량 : 가능한 예후 및 치료 임상 적용Article Published on 2022-04-012022-08-31 Journal: Journal of medical virology [Category] 바이오마커, [키워드] activity antioxidant antioxidant enzyme blood sample Blood samples catalase causative pathogen collected Concentration control group COVID-19 COVID-19 infection COVID-19 pandemic COVID-19 patient COVID-19 patients COVID-19 severity Defense dismutase Enzymes healthy individual healthy individuals healthy volunteer infected individual infected individuals Infection investigated marker Mild Mild disease nitric oxide oxidative stress Pathogenesis pathogenesis of SARS-CoV-2 Patient patients with COVID-19 Predictive prognostic Research SARS-COV-2 infection sera serum serum levels severe disease severely ill patients severity of COVID-19 statistically significant Superoxide Superoxide Dismutase susceptible TAC therapeutic Total total antioxidant capacity Variation was performed were measured with mild disease [DOI] 10.1002/jmv.27500 PMC 바로가기 [Article Type] Article
Association of the IL-6R gene polymorphic variant rs2228145(C>A) with IL-6 gene polymorphisms in a healthy cohort of Turkish population Research Published on 2022-04-012022-10-05 Journal: Genes and Immunity [Category] 바이오마커, 유전자 메커니즘, [키워드] age allele allele G allelic association Bilirubin BMI body mass index Cohort collected Comorbidity Concentration Diseases evaluated explained fasting insulin Folic acid Frequency Gender Globulin healthy hematological parameters hormone IL-6 IL-6R IL-6R gene individuals Laboratory laboratory data laboratory parameter Liver function test loci locus majority monocyte neutrophil Platelets polymorphic variant polymorphism renal rs2228145 SHBG significantly higher significantly lower subject uric acid variant Variation White blood cells [DOI] 10.1038/s41435-022-00167-7 [Article Type] Research
Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge in young adults Research Published on 2022-03-312022-10-05 Journal: Nature Medicine [Category] COVID19(2023년), SARS, 바이오마커, 변종, 임상, 진단, [키워드] 95% confidence interval acute respiratory syndrome Adults Affect Asymptomatic asymptomatic infection average caused clinical care Clinical outcome coronavirus correlation Course develop diagnose dose Efficacy Evidence Future identify immune factor Immunity implication infected individual Infection inoculated intranasally Lateral flow test median Neutralizing antibodies non-randomized Open-label participant Participants Pathogenesis peaking per-protocol analysis Primary infection public health Quantitative quarantine rapid antigen test recommendation remained reported Result rising Safety safety analysis SARS-CoV-2 SARS-CoV-2 transmission Serious Adverse Events Seroconversion serum significantly higher spike-specific IgG Symptom Symptoms TCID50 Tolerability vaccination Variation Viable viral kinetics Viral load virus Volunteer were excluded wild-type virus [DOI] 10.1038/s41591-022-01780-9 [Article Type] Research
Patients presenting to an acute general hospital with acute mental health needs: a retrospective observational cohort studyObservational Study Published on 2022-03-302022-10-04 Journal: BMJ Open [Category] 임상, [키워드] ACCIDENT & Care COVID-19 COVID-19 pandemic Diagnosis emergency medicine FIVE Health Health policy healthcare hospital hospitals liaison psychiatry lockdown London Mental mental health mental health service numbers of patient Observational cohort study Patient per day physical presenting provide recorded reduced resource resulting retrospective study period subsequent transfer Treatment Variation [DOI] 10.1136/bmjopen-2021-059102 PMC 바로가기 [Article Type] Observational Study
Randomized Evaluation of Surgery in Elderly with Traumatic Acute SubDural Hematoma (RESET-ASDH trial): study protocol for a pragmatic randomized controlled trial with multicenter parallel group design외상성 급성 경막하 혈종이 있는 고령자의 수술에 대한 무작위 평가(RESET-ASDH 시험): 다기관 병렬 그룹 설계를 사용한 실용적인 무작위 대조 시험을 위한 연구 프로토콜Article Published on 2022-03-292022-09-11 Journal: Trials [Category] 임상, [키워드] accompanied Acute subdural hematoma analyzed approval asked Belgium choice comatose Compliance Consent Consequences Conservative management conservative treatment COVID-19 crisis current discretion elderly enrolled Evidence expected foundation functional hematoma Hematoma evacuation Inclusion initial Injury intention-to-treat International midline shift multicenter Netherland Netherlands neurosurgery Neurotrauma outcome parallel group Patient patient recruitment Pragmatic primary endpoint Randomized Randomized controlled trial RCT recruited Study protocol SubDural Hematoma surgery surgical therapeutic trauma Traumatic brain injury treat Treatment Trial Variation was obtained [DOI] 10.1186/s13063-022-06184-1 PMC 바로가기 [Article Type] Article
Seasonality and reduced nitric oxide titration dominated ozone increase during COVID-19 lockdown in eastern China Research Published on 2022-03-282022-10-05 Journal: npj Climate and Atmospheric Science [Category] 치료법, [키워드] Analysis atmospheric average China Compound Concentration COVID-19 decrease dominant Emissions Factor increase increase in lockdown nitric oxide NOx Observational data Photochemistry precursor Radiation reduced reduction reduction in Region resulting seasonality solvent Variation VoC VOCs weakened Yangtze River Delta [DOI] 10.1038/s41612-022-00249-3 [Article Type] Research
Tracking the temporal variation of COVID-19 surges through wastewater-based epidemiology during the peak of the pandemic: A six-month long study in Charlotte, North Carolina전염병이 정점에 달했을 때 폐수 기반 역학을 통해 COVID-19 급증의 시간적 변화 추적: 노스캐롤라이나주 샬럿에서 6개월 동안의 연구Article Published on 2022-03-252022-09-11 Journal: The Science of the total environment [Category] SARS, 치료기술, 치료법, 치료제, [키워드] analyzed anomalies approach Asymptomatic average causative agent clinically Community Concentration coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 case COVID-19 infection Epidemiology fecal function global pandemic infected individuals influent information molecular analyses MONITOR monitoring N1 and N2 North nucleocapsid occur performed plant plants positive correlation positively correlated Prevalence qPCR quantification ranged reported RT-ddPCR RT-qPCR SARS-CoV-2 SARS-CoV-2 RNA service Spread symptomatic Treatment Variation virus wastewater wastewater-based epidemiology (WBE) WHO [DOI] 10.1016/j.scitotenv.2021.152503 PMC 바로가기 [Article Type] Article
Association of the Intermountain Risk Score with major adverse health events in patients positive for COVID-19: an observational evaluation of a US cohortObservational Study Published on 2022-03-242022-10-04 Journal: BMJ Open [Category] SARS, 임상, [키워드] 95% CI BMP calculated Care CBC Cohort Comorbidities Comorbidity complete blood count composed composite endpoint conducted COVID-19 COVID-19 diagnosis COVID-19 hospitalisation diagnosed died Epidemiology evaluated event group Health high risk hospitalisation hospitalised hypothesised identify laboratory result Laboratory results Mild moderate Mortality multivariable analyses Observational cohort study outcome parameter Patient patients positive predict predicted Predictive Preventive medicine Primary outcome Prospective public health risk RNA SARS-CoV-2 SARS-COV-2 infection score secondary outcome shown subject substantial risk tested Utah Variation Weighting [DOI] 10.1136/bmjopen-2021-053864 PMC 바로가기 [Article Type] Observational Study