clinical trial – Page 202 – Communicable Diseases Research

Efficacy and safety of DPP-4 inhibitor in the treatment of patients with COVID-19 combined with diabetes mellitus A protocol for systematic review and meta-analysis

4900

Published on 2020-10-092022-10-30
Journal: Medicine [Category] COVID-19, MERS, SARS,

[키워드] adverse outcomes Adverse reactions Analysis blood glucose CBM clinical evidence Clinical improvement clinical trial CNKI Cochrane Library conducted COVID-19 COVID-19 mortality COVID-19 patient Data analysis database diabete diabetes Diabetes Mellitus DPP-4 inhibitors effective Effectiveness Evidence fasting blood fasting insulin Glucose glycosylated hemoglobin include increase independent risk factor Infectious disease inhibitor interleukin-6 Meta-analysis metabolic disease morbidity mortality rate patients with COVID-19 peer-reviewed Primary outcome protocol Randomized controlled trials Registration review shown Symptom systematic review Treatment tumor necrosis factor-alpha VIP Web of Science with COVID-19
[DOI] 10.1097/MD.0000000000022592 PMC 바로가기 [Article Type] 4900

The IGNITE trial: Participant recruitment lessons prior to SARS-CoV-2

Article

Published on 2020-10-092022-11-01
Journal: Contemporary Clinical Trials Communications [Category] COVID-19,

Comparative docking studies to understand the binding affinity of nicotine with soluble ACE2 (sACE2)-SARS-CoV-2 complex over sACE2

Regular Article

Published on 2020-10-082022-10-29
Journal: Toxicology Reports [Category] COVID-19,

[키워드] absence Abstract ACE2 Amino acid Angiotensin-converting enzyme angiotensin-converting enzyme 2 bind binding binding affinity clinical trial Comparative complex conserved Contact COVID19 docked docking study dosage Infection inhibitory Interaction Lower neuronal Neuronal nicotinic acetylcholine receptor Nicotine patients Protein protein complex RBD domain receptor recorded reduced reducing required sACE2 sACE2 protein sACE2-INS1 complex SARS-CoV-2 SARS-CoV-2 protein sequence identity Smokers soluble ACE2 the binding affinity the healthy the SARS-CoV-2 therapeutic efficacy turn virulence
[DOI] 10.1016/j.toxrep.2020.10.002 PMC 바로가기 [Article Type] Regular Article

COVID‐19 and the pulmonary complications of sickle cell disease

Short Report

Published on 2020-10-082022-10-31
Journal: Ejhaem [Category] COVID-19,

Characteristics of academic publications, preprints, and registered clinical trials on the COVID-19 pandemic

Research Article

Published on 2020-10-062022-10-28
Journal: PLoS ONE [Category] COVID-19, MERS, SARS,

Immunobiology and immunotherapy of COVID‐19: A clinically updated overview

Review Article

Published on 2020-10-062023-06-15
Journal: Journal of cellular physiology [Category] MERS, SARS,

[키워드] clinical trial COVID‐19 Immunopathogenesis Immunotherapy SARS‐CoV‐2
[DOI] 10.1002/jcp.30076 PMC 바로가기 [Article Type] Review Article

Sofosbuvir terminated RNA is more resistant to SARS-CoV-2 proofreader than RNA terminated by Remdesivir

Article

Published on 2020-10-062022-10-04
Journal: Scientific Reports [Category] MERS, SARS, 치료제,

SARS-CoV-2: Pathogenesis, and Advancements in Diagnostics and Treatment

Immunology

Published on 2020-10-062022-11-01
Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS,

[키워드] ACE2 addition adjuvant therapy advancement antiviral agent clinical trial clinical trials Course COVID-19 determine disease effective Emmprin enzyme Genetic gold standard Host Hyperactivation immune immunoassays immunological Immunotherapy increase in less medication monoclonal antibodies monoclonal antibody Mortality multiple tissues non-structural protein novel Betacoronavirus pandemic Pathogenesis pathogenic produced Remdesivir Research RT-PCR SARS-CoV SARS-CoV-2 serologic test similarity spike receptor Spread tested the disease the SARS-CoV-2 time-consuming transmission rate Treatment strategies while
[DOI] 10.3389/fimmu.2020.570927 PMC 바로가기 [Article Type] Immunology

A review of COVID-19 vaccines in development: 6 months into the pandemic

개발 중인 COVID-19 백신에 대한 검토: 전염병 발생 6개월

Review

Published on 2020-10-052022-08-31
Journal: The Pan African Medical Journal [Category] MERS, 비임상, 신약개발, 임상,

How achievable are COVID-19 clinical trial recruitment targets? A UK observational cohort study and trials registry analysis

Infectious Diseases

Published on 2020-10-052022-10-28
Journal: BMJ Open [Category] COVID-19, Fulltext, MERS, SARS,

[키워드] Admitted Patient analysed Analysis biostatistics clinical trial clinical trials Complete Controlled COVID-19 COVID-19 pandemic database declined determine discharge eligibility England enrolled enrolment exclusion feasible First wave FIVE hospitalisation hospitalised hospitalised patient Infection Infectious diseases laboratory-confirmed SARS-CoV-2 infection limit Medical Research Council number objective Observational cohort study ongoing trials outcome measure Palliative care Pandemics participant patient cohort Population proliferation prospective observational study randomisation receiving recovery recruitment Registered required Result setting Standard Study design target Treatment Trial Trial registration trials UK Government unit were excluded with COVID-19
[DOI] 10.1136/bmjopen-2020-044566 PMC 바로가기 [Article Type] Infectious Diseases