clinical trial
[대역어] 임상시험
[용어속성] Term
[용어속성] Term
Antifibrotics in COVID-19 Lung Disease: Let Us Stay Focused
Medicine
[키워드] acute lung injury
acute respiratory distress
antifibrotics
approved
ARDS
autopsy studies
clinical trial
clinically
coronavirus disease
COVID - 19
COVID-19
curative
drugs
effective
FDA
fibrosis
full recovery
lung
Lung disease
Lung fibrosis
Lung function
MERS (middle east respiratory syndrome)
outcome
pathological finding
patients with COVID-19
Perspective
Prevalence
Repurposed drug
Research
SARS
SARS - CoV-2
severe viral pneumonia
shown
survivor
Survivors
syndrome
Therapies
therapy
treat
while
[DOI] 10.3389/fmed.2020.00539 PMC 바로가기 [Article Type] Medicine
[DOI] 10.3389/fmed.2020.00539 PMC 바로가기 [Article Type] Medicine
Subcutaneous Sarilumab in hospitalised patients with moderate-severe COVID-19 infection compared to the standard of care (SARCOVID): a structured summary of a study protocol for a randomised controlled trial
Letter
[키워드] 24 hour
7-point ordinal scale
absence
addition
administration
Admission
ALT
anticipated
assigned
AST
baseline
biological parameters
candidate
Care
clinical
Clinical research
clinical status
clinical trial
clinician
Comorbidity
conditions
Control
control arm
control group
Coronavirus infections
Council
COVID 19
COVID-19
COVID-19 infection
criteria
current
D-dimer
Day
death rate
decrease
discharge
dissemination
dose
drug
Duration
early stage
Efficacy
element
ELISA
enrolment
EudraCT
European
evaluate
exclusion criteria
exploratory
extracorporeal membrane oxygenation
Frame
harmonization
hospitalisation
hospitalised
hospitalised patient
hyperinflammatory status
hypersensitivity
Hypothesis
identify
IL-6
IL-6 levels
IL-6 receptor inhibitors
IL-6R
In-hospital
incidence
Inclusion
inclusion criteria
independent
Infection
Informed
inhibitor
interstitial pneumonia
Intervention
intervention group
intestinal perforation
Invasive mechanical ventilation
investigator
investigator-initiated
lactation
Local
marker
measure
mechanical ventilation
moderate
moderate-severe
neutrophil count
Non-invasive
non-invasive ventilation
number
number of death
objective
Open label trial
outbreak
outcome
oxygen
Oxygenation
pandemic
participant
pathogen
patients treated
performed
Platelet
Pneumonia
positive
positive RT-PCR
Positive test
Prednisone
Presence
Prevent
progression
protocol
random
randomisation
randomised
randomised controlled trial
receive
recruited
recruitment
Registered
reported
requiring supplemental oxygen
responsible
routine clinical practice
RT-PCR
SAEs
Sample size
sarilumab
SARS-CoV-2
SARS-COV-2 infection
score
Sepsis
Serious Adverse Event
serum
Severe COVID-19 Infection
single center
single dose
Spain
Standard
Standard of care
status
Study protocol
Subcutaneous
subcutaneous injection
the patient
therapy
treated
Treatment
treatment arm
treatment with tocilizumab
Trial
ULN
union
unit
verbal
website
[DOI] 10.1186/s13063-020-04588-5 PMC 바로가기 [Article Type] Letter
[DOI] 10.1186/s13063-020-04588-5 PMC 바로가기 [Article Type] Letter
Effects of Antimalarial Drugs on Neuroinflammation-Potential Use for Treatment of COVID-19-Related Neurologic Complications
Article
[키워드] activated
addition
Affect
affecting
Aminoacridine
anti-inflammatory agents
Anti-inflammatory drugs
antimalarial
Antimalarials
Aortic body
arachidonic acid
blood vessels
Brain endothelial cells
carotid body
Cell culture
Central nervous system
Chloroquine
clinical trial
CNS
combating
Complication
coronavirus
coronavirus disease
Coronavirus replication
COVID
COVID-19
COX
cPLA2
cross
cytokine
Cytokine storm
cytosolic
Cytosolic phospholipase A2
Dementia
disorder
DMT1
drug
Effect
Eicosanoids
ENhance
expression
free radical
Free radical damage
free radical formation
generate
Glossopharyngeal nerve
hippocampus
Hydroxychloroquine
Hypoxemia
impair
induce
Inflammation
Inflammatory response
inhibit
inhibiting
inhibition
inhibitor
iron accumulation
Iron transport
isoform
isoforms
lung
lysosomal enzymes
lysosome
Lysosomes
mice
Microcirculation
microglia
Microvessels
Neuroinflammation
Neurovascular
Nucleus of the tractus solitarius
organ
oxidative damage
oxidative stress
PLA2G2D
pro-inflammatory
produced
quinacrine
reducing
Respiratory centre
resulting
SARS
SARS-CoV
SARS-CoV-2
SARS-CoV-2 virus
Secretory phospholipase A2
Seizures
severe cases
shown
silent
sPLA2 IID
statins
stroke
the SARS-CoV-2 virus
tissue
TNF-α
Treatment
unique
vagus nerve
Vascular
vascular dementia
viral replication
[DOI] 10.1007/s12035-020-02093-z PMC 바로가기 [Article Type] Article
[DOI] 10.1007/s12035-020-02093-z PMC 바로가기 [Article Type] Article
Quantitative proteomic analysis of the tizoxanide effect in vero cells
Article
[키워드] Analysis
antimicrobial effect
antiviral activity
approach
approved
Bacteria
biological processes
Biotechnology
Brazil
Cell
cell metabolism
cells
circulating
clinical trial
clinical trials
COVID-19
differentially expressed
effective
engage
FASN
in vitro
in vitro results
mechanism
metabolite
microorganisms
Modification
nitazoxanide
Protein
proteomic
proteomics
RNA
Signal transduction
tizoxanide
translation
Treatment
USA
Vero Cell
viruses
[DOI] 10.1038/s41598-020-71634-2 PMC 바로가기 [Article Type] Article
[DOI] 10.1038/s41598-020-71634-2 PMC 바로가기 [Article Type] Article
Curcumin (a constituent of turmeric): New treatment option against COVID‐19
Review
[키워드] acute respiratory syndrome
alleviate
anti‐inflammatory
antiapoptotic
antifatigue
antifibrotic
antinociceptive
antioxidant
Antiviral
ARDS
attenuate
Beta coronaviruses
caused
chemokines
Clinical effect
Clinical features
clinical trial
coronavirus
coronavirus disease
Coronavirus‐19
COVID‐19
Curcuma
Curcumin
disease
Effect
effective
Effects
Inflammatory cytokine
inhibiting
inhibitory effect
medication
molecular mechanism
New
outbreak
Pathogenesis
Patient
patients
pulmonary fibrosis
receptors
reduce
Respiratory illness
SARS‐CoV‐2
scientific evidence
scientist
Signaling
Spread
Symptom
therapeutic effect
treat
Treatment
virus
WHO
World Health Organization
Wuhan, China
[DOI] 10.1002/fsn3.1858 PMC 바로가기 [Article Type] Review
[DOI] 10.1002/fsn3.1858 PMC 바로가기 [Article Type] Review
Azithromycin in addition to standard of care versus standard of care alone in the treatment of patients admitted to the hospital with severe COVID-19 in Brazil (COALITION II): a randomised clinical trial
Research article
[키워드] 1:1
acute kidney failure
acute respiratory syndrome
addition
administration
adverse events
Arrhythmias
assigned
Azithromycin
Brazil
clinical status
clinical trial
clinically
Combination
control group
coronavirus
COVID-19
criteria
Efficacy and safety
enrolled
finding
funding
greater
groups
hospital
Hydroxychloroquine
improve clinical outcome
improve clinical outcomes
independent
Infection
intention-to-treat
intravenous
Invasive mechanical ventilation
ITT
mITT population
molecular
nasal
Non-invasive
not significantly different
Odds ratio
Open-label
oxygen supplementation
Patient
Primary outcome
QT interval
randomisation
randomised
Randomly
Rate
Registered
Safety
Serological testing
severe COVID-19
severity
Standard of care
Support
the primary endpoint
Treatment
treatment allocation
Trial
ventricular
[DOI] 10.1016/S0140-6736(20)31862-6 [Article Type] Research article
[DOI] 10.1016/S0140-6736(20)31862-6 [Article Type] Research article
Potential Role of Acacia Senegal (Gum Arabic) as Immunomodulatory Agent among newly diagnosed COVID 19 Patients: A structured summary of a protocol for a randomised, controlled, clinical trial
Letter
[키워드] 1:1
Acacia
addition
agent
Anti-inflammatory
Arabic
assigned
assistant
baseline
baseline value
blind
change
Clinical guidelines
clinical trial
computer-generated
conducted
Control
COVID
COVID 19
COVID 19 patient
COVID-19
COVID-19 patients
CRP
Cytokines
Date
death
diagnosed
dissemination
Efficacy
element
eligible patient
Factor
Gender
group
groups
Gum
Gum Arabic
Hospital admission
IL10
IL6
IL8
immunomodulation
immunomodulatory
independent
Intervention
Local
mortality rate
number
objective
outcome
parallel-group
participant
Patient
patients
PCR
Pectin
phase
Placebo
placebo-controlled clinical trial
Potential
Prospective
protocol
provided
random
randomised
randomised controlled trial
randomization
Randomized
Randomly
Real-time PCR
receive
Research
response
role
Sample size
secondary
sequence
seropositive
Soba
standard care
state
status
TNFα
Treatment
Trial
Tumor
Two-arm
university
Version
Viral load
website
[DOI] 10.1186/s13063-020-04707-2 PMC 바로가기 [Article Type] Letter
[DOI] 10.1186/s13063-020-04707-2 PMC 바로가기 [Article Type] Letter
How to deal with a temporary suspension and restarting your trial: our experiences and lessons learnt
Commentary
[키워드] activity
clinical trial
COVID-19
COVID-19 pandemic
File
Follow-up
Guidance
help
implementation
Intervention
randomised controlled trial
RCT
RCTs
recruitment
risk
Suspend
Temporary suspension
Trial
trial protocol
[DOI] 10.1186/s13063-020-04705-4 PMC 바로가기 [Article Type] Commentary
[DOI] 10.1186/s13063-020-04705-4 PMC 바로가기 [Article Type] Commentary
The relationship between hyperglycemia and the infection of COVID-19 in diabetic patients A protocol for systematic review and meta-analysis
4900
[키워드] ACE2 receptor
acute inflammatory reactions
adverse effects
bias risk
binding
blood glucose
CBM
Chinese
clinical evidence
clinical trial
CNKI
Cochrane Library
combating
Comorbidity
COVID-19
COVID-19 epidemic
COVID-19 infection
Cytokine storms
Data analysis
database
Diabetes Mellitus
diabetic patient
diabetic patients
English
fasting blood
fasting insulin
Glucose
hemoglobin
hyperglycemia
include
independent risk factor
Infection
Infectious disease
Meta-analysis
metabolic disease
Mild
pancreatic islet
peer-reviewed
Primary outcome
protocol
Randomized controlled trials
Registration
Regulation
review
risk factor
RNA coronavirus
SARS-COV-2 infection
sensitivity analysis
severe disease
Severe infection
single-stranded
Stress
Support
systematic review
VIP
virus
Web of Science
[DOI] 10.1097/MD.0000000000021806 PMC 바로가기 [Article Type] 4900
[DOI] 10.1097/MD.0000000000021806 PMC 바로가기 [Article Type] 4900