Targeting SARS-CoV-2 receptors as a means for reducing infectivity and improving antiviral and immune response: an algorithm-based method for overcoming resistance to antiviral agentsReview Published on 2020-06-182022-10-31 Journal: Emerging Microbes & Infections [Category] COVID-19, MERS, SARS, [키워드] ACE acute respiratory syndrome Antiviral antiviral agent antiviral drug antiviral therapy association blocker blockers caused characterized coronavirus COVID-19 disease described DPP4 effective Effectiveness Efficacy Hyperactivation immune immune system Immune-mediated IMPROVE Inflammatory response initial morbidity and mortality Novel coronavirus organ damage overcome pandemic Pathogenesis patients platform receptor receptors reducing SARS-CoV-2 SARS-CoV-2 receptor sustained targeting the SARS-CoV-2 therapeutic option Treatment Variability Viral resistance [DOI] 10.1080/22221751.2020.1776161 PMC 바로가기 [Article Type] Review
SARS-CoV-2 (COVID 19) Infection in Hypertensive Patients and in Patients With Cardiac DiseaseCardiology Published on 2020-06-112022-10-31 Journal: Cureus [Category] COVID-19, [키워드] ACE acute respiratory distress syndrome association blockers cardiac cardiac function cardiovascular comorbidity caused Comorbidities contracting the virus Coronary artery disease coronary disease coronavirus country COVID 19 described effort enzyme II expression global pandemic greater heart failure hypertension idiopathic hypertension increased risk ischemic heart disease less management mechanism medical condition morbidity and mortality Novel coronavirus Patient patients prescribed medications reported risk SARS-CoV-2 sars-cov-2 (severe acute respiratory syndrome coronavirus -2) Scientific community serious infection Society Spread the disease the SARS-CoV-2 virus Western world Wuhan, China [DOI] 10.7759/cureus.8557 PMC 바로가기 [Article Type] Cardiology
Genetic gateways to COVID‐19 infection: Implications for risk, severity, and outcomesArticle Published on 2020-06-112023-07-02 Journal: FASEB journal : official publication of the Federa [Category] SARS, [키워드] ACE COVID‐19 Cytokine storm genetics HLA Immunity SARS‐CoV‐2 [DOI] 10.1096/fj.202001115R PMC 바로가기
Renin-angiotensin system inhibition in COVID-19 patientsPoint of View Published on 2020-06-082022-10-30 Journal: Netherlands Heart Journal [Category] COVID-19, [키워드] ACE ACE2 ACEi ACEIs acute respiratory syndrome Angiotensin II type‑1 receptor blocker Angiotensin-converting enzyme angiotensin-converting enzyme 2 angiotensin-converting enzyme inhibitor ARB ARBs Arterial hypertension blocker cell entry receptor Chronic kidney disease Clinical data coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient drug drugs enzyme Evidence expression globe heart failure Hypothesis indicated infections inhibitor likelihood Lungs outcome receptor recommendation renin-angiotensin system Research risk SARS-CoV-2 SARS-CoV‑2 Severe acute respiratory syndrome coronavirus 2 severe COVID-19 Treatment [DOI] 10.1007/s12471-020-01439-5 PMC 바로가기 [Article Type] Point of View
COVID-19 in India: Are Biological and Environmental Factors Helping to Stem the Incidence and Severity?Perspective Published on 2020-06-022022-10-28 Journal: Aging and Disease [Category] COVID-19, [키워드] ACE ACE2 Biological Community Corona virus COVID-19 COVID-19 disease Cross-immunity curtail Factor genetic mutation Government India innate immune responses lockdown marker Mortality pandemic Perspective polymorphism proportions response SARS-CoV-2 transmission spread of COVID-19 STEM Transmission while [DOI] 10.14336/AD.2020.0402 PMC 바로가기 [Article Type] Perspective
Effects of host genetic variations on response to, susceptibility and severity of respiratory infectionsArticle Published on 2020-05-292023-06-15 Journal: Biomedicine & pharmacotherapy = Biomédecine & phar [Category] MERS, SARS, [키워드] ACE COVID-19 Genetic respiratory tract infection SARS-CoV-2 Single nucleotide polymorphism [DOI] 10.1016/j.biopha.2020.110296 PMC 바로가기 [Article Type] Article
Impact of sex and gender on COVID-19 outcomes in EuropeReview Published on 2020-05-252022-10-28 Journal: Biology of Sex Differences [Category] COVID-19, MERS, SARS, [키워드] ACE acute respiratory syndrome Adaptive immune response analyses antiviral therapies cardiovascular conditions China Chinese condition content coronavirus coronavirus disease Course COVID-19 develop disease entry receptor enzyme epidemiological Europe European country Evidence expression of gene fatality Fatality rate Gender Health highest immune system Impact incidence include mechanism men modulating offer outcome Prophylactic Psychological receptor reduced Renin angiotensin aldosterone system reported risk stratification SARS-CoV2 Sex Sex difference Stress the disease therapeutic option Therapeutic treatment TMPRSS2 Treatment women [DOI] 10.1186/s13293-020-00304-9 PMC 바로가기 [Article Type] Review
COVID-19: Dados Atualizados e sua Relação Com o Sistema CardiovascularPonto de Vista Published on 2020-05-222022-10-28 Journal: Arquivos Brasileiros de Cardiologia [Category] COVID-19, MERS, SARS, [키워드] ACE ACE2 acute respiratory syndrome addition angiotensin receptor blocker Angiotensin-converting enzyme association benefit cardiovascular Cardiovascular Diseases/complications Cell cerebrovascular diseases Chronic diseases conditions coronavirus coronavirus disease cough COVID 19 COVID-19 diabetes diabetic patients Disease progression Doenças Cardiovasculares/complicações Doenças Infecciosas drug drugs ECA2 Evidence example Fatores de Risco/prevenção e controle Fever Final headache Health heart muscle hypertensive Immune system disorder include increase in individual infecção Infection Infectious diseases Inflammatory response inhibitor Miocardite myocarditis pandemic patients hospitalized penetrate professional PROTECT receptors resposta inflamatória risk Risk Factors/prevention and control Síndrome Respiratória Aguda SARS-CoV-2 Shortness of breath spreading Support Symptom systemic turn virus weighed Withdrawal World Health Organization worse prognosis Wuhan, China [DOI] 10.36660/abc.20200215 PMC 바로가기 [Article Type] Ponto de Vista
Facts and reflections on COVID-19 and anti-hypertensives drugsArticle Published on 2020-05-062023-07-13 Journal: Drug discoveries & therapeutics [Category] SARS, [키워드] ACE Anti-hypertensive drugs ATII-RB COVID-19 SARS-CoV-2 [DOI] 10.5582/ddt.2020.01017
ACE2, COVID19 and serum ACE as a possible biomarker to predict severity of disease질병의 중증도를 예측하는 가능한 바이오마커로서의 ACE2, COVID19 및 혈청 ACEArticle Published on 2020-05-012022-09-11 Journal: Journal of Clinical Virology [Category] MERS, 바이오마커, [키워드] ACE ACE2 Biomarker COVID19 predict serum Severity of disease [DOI] 10.1016/j.jcv.2020.104350 PMC 바로가기 [Article Type] Article