Effects of different types of written vaccination information on COVID-19 vaccine hesitancy in the UK (OCEANS-III): a single-blind, parallel-group, randomised controlled trial영국(OCEANS-III)의 COVID-19 백신 주저에 대한 다양한 유형의 서면 예방 접종 정보의 영향: 단일 맹검, 병렬 그룹, 무작위 대조 시험Articles Published on 2021-05-132022-08-13 Journal: The Lancet. Public Health [Category] 임상, [키워드] 95% CI addition addressed adjusted Adults Alter analysed assigned benefit Combination condition confidence control condition Controlled trial COVID-19 COVID-19 vaccination COVID-19 vaccination programme COVID-19 vaccine COVID-19 vaccines Decision making Effect effective Effectiveness Efficacy and safety engage Ethnicity finding funding Gender greater group Health health campaigns Hesitancy highlight information ISRCTN less mean difference moderate multiple comparisons National Health Service NIHR NIHR Oxford Health Biomedical Research Centre outcome outcome measure outcomes Oxford Oxford Biomedical Research Centre Oxford COVID-19 Vaccine Hesitancy Scale Oxford Vaccine Confidence and Complacency Scale p values pandemic parallel-group participant Perception Primary outcome public health communications randomised controlled trial Randomly recruit recruited recruitment reduce reduced Registered risk scale seriousness single-blind speed stratified terrain vaccination Vaccine Vaccine hesitancy vaccine hesitancy scale vaccine-hesitant virus was reduced [DOI] 10.1016/S2468-2667(21)00096-7 PMC 바로가기 [Article Type] Articles
The safety and immunogenicity of an inactivated SARS-CoV-2 vaccine in Chinese adults aged 18-59 years: A phase I randomized, double-blinded, controlled trial18-59세 중국 성인을 대상으로 한 비활성화된 SARS-CoV-2 백신의 안전성 및 면역원성: 1상 무작위, 이중 맹검, 대조 시험Clinical Trial Published on 2021-05-122022-09-12 Journal: Vaccine [Category] MERS, SARS, 비임상, 임상, 진단, [키워드] Administered Adverse reaction antibody Chinese Controlled trial CTL cytokine cytotoxic T lymphocyte dose double-blinded evaluated examined fatigue genetic diversity geometric mean titer GMTs healthy Immune cell immune response immunogenic immunopathology inactivated Inactivated vaccine injection intervals intramuscularly Mild N protein occurred Pain phase Phase I Placebo placebo-controlled trial Randomized Safe SARS-CoV-2 SARS-CoV-2 vaccine seroconversion rate subjects synchronous the S protein the vaccine transcriptome analysis Trial upregulation virion [DOI] 10.1016/j.vaccine.2021.04.006 PMC 바로가기 [Article Type] Clinical Trial
Randomized controlled trial of convalescent plasma therapy against standard therapy in patients with severe COVID-19 disease중증 COVID-19 질환 환자의 표준 요법에 대한 회복기 혈장 요법의 무작위 대조 시험Randomized Controlled Trial Published on 2021-05-112022-08-13 Journal: Scientific Reports [Category] SARS, 임상, 치료기술, 치료법, [키워드] 95% CI appear biochemical parameter Biochemical parameters clinical Clinical outcome confirmation Control Controlled trial convalescent patient Convalescent plasma therapy COVID-19 disease COVID-19 patient CP group died feasibility ferritin ferritin level higher risk hospitalized COVID-19 patient hospitalized COVID-19 patients hypoxia IMPROVE measure mechanical ventilation Mortality NIV no difference no differences no significant difference no significant differences Non-invasive not differ one patient open open label Patient pilot study plasma Primary outcome primary outcome measure Randomized Randomized controlled trials required respiratory indice respiratory indices risk risk ratio Safe secondary outcome secondary outcome measure Secondary outcomes severe COVID-19 severe COVID-19 disease severe disease Standard of care Standard therapy therapy Trial Two patient two patients Ventilation Virology [DOI] 10.1038/s41598-021-89444-5 PMC 바로가기 [Article Type] Randomized Controlled Trial
Study protocol of the Edinburgh and Lothian Virus Intervention Study in Kids: a randomised controlled trial of hypertonic saline nose drops in children with upper respiratory tract infections (ELVIS Kids)어린이에 대한 에딘버러 및 로시안 바이러스 중재 연구의 연구 프로토콜: 상부 호흡기 감염이 있는 어린이의 고장성 식염수 점비제에 대한 무작위 대조 시험(ELVIS Kids)Article Published on 2021-05-052022-09-11 Journal: BMJ Open [Category] SARS, 임상, [키워드] 24 hour 24 hours 48 hour 48 hours age All participant All participants approved asked Asymptomatic board Care Child child health children chloride clinical Community community child health Complete Contact control arm Controlled trial determine Edinburgh Ethics events Health hypertonic hypertonic saline immunisation Infection Infectious disease Intervention intervention arm Local media nasal swab National Health Service neonatology nose drop nose drops nostril office Open-label paediatric infectious disease & Participation partnership peer-reviewed primary care protocol provided questionnaire randomised randomised controlled trial recruited recruitment registration number Research Research Ethics satisfaction questionnaire service Sodium chloride standard care Symptom symptomatic university upper respiratory tract upper respiratory tract infection URTI URTI symptom URTI symptoms Virology website West wheeze [DOI] 10.1136/bmjopen-2021-049964 PMC 바로가기 [Article Type] Article
Effect of intensive care unit-specific virtual reality (ICU-VR) to improve psychological well-being and quality of life in COVID-19 ICU survivors: a study protocol for a multicentre, randomized controlled trialCOVID-19 ICU 생존자의 심리적 웰빙과 삶의 질을 개선하기 위한 중환자실별 가상 현실(ICU-VR)의 효과: 다기관, 무작위 통제 시험을 위한 연구 프로토콜Study Protocol Published on 2021-05-052022-09-10 Journal: Trials [Category] SARS, 임상, [키워드] 1:1 Admission aftercare Anxiety can be used changes in clinic visit Controlled trial coronavirus disease Coronavirus disease 2019 Coronavirus disease 2019 (COVID-19) COVID-19 Depression develop dimension Effect effective EQ-5D European expected Follow-up HADS Health-related quality of life (HRQoL) hospital hospital discharge ICU ICU care ICU treatment IES-R illness Impact IMPROVE increase in intensive care Intervention life mechanical ventilation modality multicentre Netherland Netherlands offered outbreak outcome outpatient clinic patients randomized patients treated Perspective Post-intensive care syndrome (PICS) Post-traumatic stress disorder Post-traumatic stress disorder (PTSD) Primary outcomes Psychological Psychological well-being PTSD Quality Quality of life Questionnaires Randomized Randomized controlled trial receive Registered Result SARS-CoV-2 Satisfaction scale Secondary objective Secondary objectives severe coronavirus disease Study protocol supplementary material Treatment Trial Trial registration virtual reality [DOI] 10.1186/s13063-021-05271-z PMC 바로가기 [Article Type] Study Protocol
Addressing COVID-19 challenges in a randomised controlled trial on exercise interventions in a high-risk populationRandomized Controlled Trial Published on 2021-05-012022-10-04 Journal: BMC Geriatrics [Category] 임상, [키워드] addition Aged changes in chronic disease clinical trial Complete complex complications conducted Controlled trial coronavirus disease COVID-19 COVID-19 situation E-health Efficacy equipment Eurythmy therapy exercise Exercise intervention expected Falls feasibility group groups Healthcare provider healthy high risk high-risk population identify implementation individual individuals International interview involved limitation literature review lockdown management National outcomes pandemic participant Participation Patient performed physical randomised controlled trial researcher resolved resources Result risk social contact solution Study design study population subsequent Tai Chi Telemedicine Trial trial participant trials [DOI] 10.1186/s12877-021-02232-8 PMC 바로가기 [Article Type] Randomized Controlled Trial
Addressing COVID-19 challenges in a randomised controlled trial on exercise interventions in a high-risk populationRandomized Controlled Trial Published on 2021-05-012022-10-27 Journal: BMC Geriatrics [Category] COVID-19, [키워드] addition Aged changes in chronic disease clinical trial Complete complex complications conducted Controlled trial coronavirus disease COVID-19 COVID-19 situation E-health Efficacy equipment Eurythmy therapy exercise Exercise intervention expected Falls feasibility group groups Healthcare provider healthy high risk high-risk population identify implementation individual individuals International interview involved limitation literature review lockdown management National outcomes pandemic participant Participation Patient performed physical randomised controlled trial researcher resolved resources Result risk social contact solution Study design study population subsequent Tai Chi Telemedicine Trial trial participant trials [DOI] 10.1186/s12877-021-02232-8 PMC 바로가기 [Article Type] Randomized Controlled Trial
Addressing COVID-19 challenges in a randomised controlled trial on exercise interventions in a high-risk populationRandomized Controlled Trial Published on 2021-05-012022-10-27 Journal: BMC Geriatrics [Category] Coronavirus, COVID-19, SARS, [키워드] addition Aged changes in chronic disease clinical trial Complete complex complications conducted Controlled trial coronavirus disease COVID-19 COVID-19 situation E-health Efficacy equipment Eurythmy therapy exercise Exercise intervention expected Falls feasibility group groups Healthcare provider healthy high risk high-risk population identify implementation individual individuals International interview involved limitation literature review lockdown management National outcomes pandemic participant Participation Patient performed physical randomised controlled trial researcher resolved resources Result risk social contact solution Study design study population subsequent Tai Chi Telemedicine Trial trial participant trials [DOI] 10.1186/s12877-021-02232-8 PMC 바로가기 [Article Type] Randomized Controlled Trial
Randomized controlled trials for alcohol use disorder during the COVID-19 pandemicCOVID-19 전염병 동안 알코올 사용 장애에 대한 무작위 대조 시험Editorial Published on 2021-05-012022-09-11 Journal: Alcohol (Fayetteville, N.Y.) [Category] 임상, [키워드] activities acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 alcohol assessment complexity Controlled trial coronavirus COVID-19 COVID-19 pandemic disorder Efficacy limitation logistics medication medications mental health mental health professional pandemic Randomized controlled trial RCT RCTs reduce required Research SARS-CoV-2 [DOI] 10.1016/j.alcohol.2021.01.001 PMC 바로가기 [Article Type] Editorial
Instructional interventions for improving COVID-19 knowledge, attitudes, behaviors: Evidence from a large-scale RCT in IndiaRandomized Controlled Trial Published on 2021-05-012022-10-05 Journal: Social science & medicine (1982) [Category] SARS, 임상, [키워드] affecting appear assigned Attitudes Behavioral interventions Compliance Controlled trial COVID-19 knowledge Health Health beliefs health economics Health Education hypothese improvement India Intervention knowledge pandemic Pandemics provided Randomized controlled trials (RCT). Randomly RCT reducing relative sustained Treatment [DOI] 10.1016/j.socscimed.2021.113846 PMC 바로가기 [Article Type] Randomized Controlled Trial