Characterisation of 22445 patients attending UK emergency departments with suspected COVID-19 infection: Observational cohort studyObservational Study Published on 2020-11-252022-10-04 Journal: PLoS ONE [Category] MERS, SARS, 임상, [키워드] Admission adverse outcome age approach Asian black children cohort study collected Comorbidity COVID-19 COVID-19 infection COVID-19 test death discharged female greater hospital initial ISRCTN less Lung disease male management median median age men men and women much lower NEWS2 Observational cohort study organ support Patient patient group performance status positive COVID-19 presenting rates of admission Registration renal retrospective Sex subgroup United Kingdom white worse prognosis [DOI] 10.1371/journal.pone.0240206 PMC 바로가기 [Article Type] Observational Study
Social Determinants Predict Outcomes in Data From a Multi-Ethnic Cohort of 20,899 Patients Investigated for COVID-19Public Health Published on 2020-11-242022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] analyses Analysis Care caused close contact COVID-19 COVID-19 mortality COVID-19 pandemic COVID-19 test cross death determinant died digit disease effort English evaluate examined Health healthcare highlight Hospitalization Hospitalized implication Improvements Intubated intubation morbidity Mortality Mount Sinai multi-ethnic multivariable logistic regression New York City outcome outcomes Patient patients populations positive predictor Region risk SARS-CoV-2 secondary outcome setting Sex social determinant social determinants of health Symptom System tested Travel was performed [DOI] 10.3389/fpubh.2020.571364 PMC 바로가기 [Article Type] Public Health
The Impact of Periodontal Disease on Hospital Admission and Mortality During COVID-19 PandemicMedicine Published on 2020-11-232022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] adjusted adjusted odds ratio Biomarkers bleeding BMI co-morbidities Control control group controls COVID-19 COVID-19 infection COVID-19 negative COVID-19 pandemic COVID-19 test demographics disease Evidence Health healthcare higher risk hospital Hospital admission Impact IMPROVE increased risk Infection Logistic regression material Mortality Odds ratio oral health outcome outcomes participant Patient periodontal periodontal disease positive reported risk significantly higher subsequent suggested the disease UK biobank utilization were used with COVID-19 [DOI] 10.3389/fmed.2020.604980 PMC 바로가기 [Article Type] Medicine
Glasgow Early Treatment Arm Favirpiravir (GETAFIX) for adults with early stage COVID-19: A structured summary of a study protocol for a randomised controlled trialLetter Published on 2020-11-192022-10-29 Journal: Trials [Category] COVID-19, SARS, [키워드] 1:1 48 hours able to swallow accompany addition age Alexandra Algorithm ALT Antiviral Arm AST authority baseline Blinding Breastfeeding childbearing clinical clinically clinician co-morbidities co-morbidity Concomitant medication contribute control arm COVID COVID-19 COVID-19 infection COVID-19 test death defined dialysis disease dissemination doses drug duration of symptom early early stage effective Efficacy eight element Elizabeth EudraCT European excluded experimental arm Factor Favipiravir female females first positive greater haemofiltration Health hereditary xanthinuria history hospital hospitalisation hypersensitivity hypertension Hypothesis impairment in-patient Infection Infirmary information Inpatient ISARIC4C ISRCTN Loading dose maintenance dose male measure mechanism medication men metabolite negative number obesity objective offered open label Other outcome Outpatient Oxygen therapy parallel group participant Patient patients patients with COVID-19 pharmacokinetic pharmacokinetics Point positive pregnancy test pregnant Primary outcome principal investigator protocol random randomisation randomised randomised controlled trial Randomised trial receive recruit recruited recruitment reducing reference Registered Regulating reported risk risk of death Safety Sample size SARS-CoV-2 sequence severe hepatic impairment severity Severity of disease Sex Standard Standard of care standard treatment standard treatment alone status Study protocol Symptom the primary endpoint the WHO Tolerability Total treated Treatment treatment allocation treatment for COVID-19 Trial ULN undergo union university website WHO with COVID-19 women [DOI] 10.1186/s13063-020-04891-1 PMC 바로가기 [Article Type] Letter
Facing a Second Wave from a Regional View: Spatial Patterns of COVID-19 as a Key Determinant for Public Health and Geoprevention PlansArticle Published on 2020-11-162022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] Action Affect Analysis ArcGIS Cantabria contribute coronavirus country COVID-19 COVID-19 pandemic COVID-19 research COVID-19 test determinant distribution ethics committee geocoding Geographic geographic information technologies geoprevention Health authority include Johns Hopkins University knowledge Medicine methodology microdata Outbreaks pandemic pattern Perspective plan positive result provided Public public health random Regional Research second Socioeconomic factor Spain Spanish spatial information spatial patterns Spread System technology Wave [DOI] 10.3390/ijerph17228468 PMC 바로가기 [Article Type] Article
Unmet clinical needs for COVID-19 tests in UK health and social care settingsResearch Article Published on 2020-11-122022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] accelerate Antibiotics Care clinical setting COVID-19 COVID-19 test diagnostic test diagnostics expressed Health identify Laboratory limit molecular patients professional PROTECT Rapid response symptomatic Transmission urgency widespread [DOI] 10.1371/journal.pone.0242125 PMC 바로가기 [Article Type] Research Article
A stoic and altruistic orientation towards their work: a qualitative study of healthcare professionals’ experiences of awaiting a COVID-19 test resultResearch Article Published on 2020-11-112022-10-28 Journal: BMC health services research [Category] COVID-19, [키워드] 2019-nCoV Community coronavirus COVID-19 COVID-19 infection COVID-19 test discrepancy Extensive Health healthcare Healthcare professional healthcare professionals identity measure mental health outbreak parameter performed Qualitative qualitative study reduce reducing required Result risk risk of infection suggested Testing Transmission [DOI] 10.1186/s12913-020-05904-0 PMC 바로가기 [Article Type] Research Article
Comparison of two different frailty measurements and risk of hospitalisation or death from COVID-19: findings from UK BiobankResearch Article Published on 2020-11-102022-10-28 Journal: BMC Medicine [Category] COVID-19, SARS, [키워드] adjusted age Analysis association baseline coronavirus COVID-19 COVID-19 infection COVID-19 mortality COVID-19 test COVID19 death died disease England Factors frailty Health higher risk hospital Hospital admission Hospital stay hospitalisation hospitalisations independent individual Mental Mild participant phenotype Poisson regression model preventive measure provided Public Public Health England questionnaire recruited reported required Result resulting risk Risk factors robust Severe COVID-19 Infection Severe infection Sociodemographic standard error to define UK biobank was measured was used were used while women worse prognosis [DOI] 10.1186/s12916-020-01822-4 PMC 바로가기 [Article Type] Research Article
Association of poor housing conditions with COVID-19 incidence and mortality across US countiesResearch Article Published on 2020-11-022022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] adjusted adverse outcome association census center Characteristics Comorbidities condition conditions conducted Control COVID-19 COVID-19 incidence COVID-19 mortality COVID-19 test cross-sectional analysis death demographics effort greater Health healthcare higher risk incidence incidence rate increase in individual Infectious disease investigated linear modeling mitigate Mortality mortality rate ratio objective outcome Poor Prevalence remained Result risk Spread Support the mean timepoint total population with COVID-19 [DOI] 10.1371/journal.pone.0241327 PMC 바로가기 [Article Type] Research Article
BCG revaccination of health workers in Brazil to improve innate immune responses against COVID-19: A structured summary of a study protocol for a randomised controlled trialCOVID-19에 대한 타고난 면역 반응을 개선하기 위해 브라질에서 의료 종사자의 BCG 재접종: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2020-10-262022-08-13 Journal: Trials [Category] MERS, SARS, 임상, [키워드] accompany activate acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 Admission Antibiotics antiviral immune response approved assigned Autoimmune Autoimmune diseases Bacillus BCG BCG revaccination BCG vaccination bcg vaccine blinded Blinding block blocks both groups Brazil Breastfeeding carried CFU Characteristics Chemotherapy childhood city clinical trial Committee Comorbidities Comorbidity confirmation Contact contact with control group Coronavirus-2 COVID-19 COVID-19 patient COVID-19 severity COVID-19 symptoms COVID-19 test cross-protection determined by diagnosed direct contact disease disease severity Diseases dissemination dose doses Effectiveness element elicited eligibility criteria Fever health worker health workers healthcare providers HIV hospital Hypothesis ICU identification number IgG and IgM IgM and IgG IgM test immunosuppressive IMPROVE in both group incidence incidence of COVID-19 Inclusion inclusion criteria India induce Infection infections information innate immune response investigator Laboratory lateral flow less macrophages medication meet memory monocyte Monocytes Mortality naso-oropharyngeal swab neutrophil Neutrophils NK NK cell number Nurses objective Open-label outcome outcomes pandemic parallel-group participant physiotherapists platform presenting Prevent Primary outcome Primary outcomes professional protocol randomisation randomised randomised controlled trial randomization Randomized receive recruit recruitment reduce Registered registration number researcher researchers respiratory revaccination right arm RT-PCR Sample size SARS-CoV-2 scar sealed Secondary objective Secondary objectives secondary outcome severe acute respiratory syndrome Coronavirus severity solid tumour specimen statistical analyses status steroid Study protocol Symptom symptomatic infection the disease the vaccine Trial Trial registration Tuberculosis two groups vaccination Vaccine virus virus infection virus infections was performed website WHO [DOI] 10.1186/s13063-020-04822-0 PMC 바로가기 [Article Type] Letter