Dynamic miRNA-mRNA interactions coordinate gene expression in adult Anopheles gambiae동적 miRNA-mRNA 상호 작용은 성인 Anopheles gambiae에서 유전자 발현을 조정합니다Research Article Published on 2020-04-272022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] 3’ end Anopheles gambiae approach binding site biological processe canonical captures changes in characterized complementary complexes contribute Critical dataset demonstrated Diseases dynamic exhibited female flexibility function functional Gene Expression Gene regulation identification in vivo increasingly indicated Infectious diseases Interaction involved majority metabolism microRNA MicroRNAs miRNA miRNA target miRNA-mRNA interaction miRNA-mRNA interactions miRNAs more difficult motif motifs mRNA abundance mRNAs Organisms pairing rules physiological provide provided Regulation Regulatory reliability reported RNA sequence SIX4 specificity Stage target targets transcript vector vectors widespread [DOI] 10.1371/journal.pgen.1008765 PMC 바로가기 [Article Type] Research Article
Prediction of Epidemic Spread of the 2019 Novel Coronavirus Driven by Spring Festival Transportation in China: A Population-Based StudyArticle Published on 2020-03-042022-10-30 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, SARS, [키워드] 2019 novel coronavirus 2019-nCoV Analysis Characteristics China Community confirmed case confirmed cases correlated cumulative distribution dynamic Festival include individuals Migration novel nuclear outbreak Population size prediction proportion quasi-experimental approach reduction Region regions returned social characteristics of floating population spring survey the epidemic the origins of Wuhan’s migrants Wuhan [DOI] 10.3390/ijerph17051679 PMC 바로가기 [Article Type] Article
A Novel Dynamic Model Describing the Spread of the MERS-CoV and the Expression of Dipeptidyl Peptidase 4Research Article Published on 2017-08-152022-10-31 Journal: Computational and Mathematical Methods in Medicine [Category] Coronavirus, MERS, [키워드] attack bronchiolar cause caused cells coronavirus defined Describing Dipeptidyl peptidase 4 DPP4 dynamic endothelial epithelial cell expressed expression humans Infection MERS MERS-CoV Middle East Model novel pathogen peptidase receptor Respiratory system severe pneumonia shown Spread stability syndrome [DOI] 10.1155/2017/5285810 PMC 바로가기 [Article Type] Research Article
Tissue- and Time-Specific Expression of Otherwise Identical tRNA Genes다른 동일한 tRNA 유전자의 조직 및 시간 특이적 발현Research Article Published on 2016-08-252022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] abrogate adaptive addition Affect affected age aggregation Amino acid Caenorhabditis Caenorhabditis elegan Caenorhabditis elegans can not changes in codon codon usage conserved disease Diseases dynamic eight element expressed expression expression level expression levels fluorescent Genes genome-wide analysis GFP hallmark Host identity intrinsic intron Intronic introns lead MONITOR mutations nematodes neurodegeneration observation orthologous gene orthologous genes Pairing predict promoter promoters Protein Protein misfolding protein sequences protein translation protein-coding gene protein-coding genes recognize regulated Regulating reporter ribosome sequence synonymous tissue tissues transcribed tRNA tRNAs Tryptophan [DOI] 10.1371/journal.pgen.1006264 PMC 바로가기 [Article Type] Research Article
Sequence of a Complete Chicken BG Haplotype Shows Dynamic Expansion and Contraction of Two Gene Lineages with Particular Expression Patterns완전한 치킨 BG 일배체형의 시퀀스는 특정 발현 패턴을 가진 두 유전자 계통의 동적 확장 및 수축을 보여줍니다Research Article Published on 2014-06-052022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] Actin allelic Antigen presentation appear association Autoimmune disease Autoimmune diseases B12 brush border Cell cells change chicken chromosome chromosome 2 CNV complex contraction copy number Deletion domain dynamic Evolution expansion expressed expression family fixed Genes genetic association genetic associations Haplotype haplotypes homolog homologue homologues Human humans identify immune immune gene immune genes Immunity implicated Interaction intestinal involved major histocompatibility complex mammal mammals MHC multigene families multigene family myosin Particular pathogen Pathogens pattern polymorphism promoter promoters Recombination Region scrutiny sequence show single gene species tandem repeats the major histocompatibility tissue tissue expression tissues undergo untranslated regions Variation Viral diseases whole genome [DOI] 10.1371/journal.pgen.1004417 PMC 바로가기 [Article Type] Research Article
Integrative “Omics”-Approach Discovers Dynamic and Regulatory Features of Bacterial Stress Responses통합 "Omics" 접근 방식으로 세균 스트레스 반응의 동적 및 조절 기능 발견Research Article Published on 2013-06-202022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] (transcriptome adaptation adaptive mechanism adaptive mechanisms addition alternative approach assigned Author Bacteria cellular stress responses change choice complex conditions determine different dynamic Effect elevated temperature event events example exhibited expression expression level expression pattern expressome Factor Factors feature found fraction Frequency Gene Genes Genome help in addition to include initiated integration maintain mass spectrometry Microarrays mRNA mRNA level mRNA levels mRNAs Occurrence open reading frames operon organism oxygen phototrophic polar polysome Population post-transcriptional level Protein Proteins proteome provided quantification quorum regulated Regulation Regulatory reported required response RNA-Seq RpoE singlet oxygen Stress stress condition stress conditions stress response stress responses survival transcriptional activation transcriptional level transcriptional regulator transcriptional regulators Transcriptome translation translational was used [DOI] 10.1371/journal.pgen.1003576 PMC 바로가기 [Article Type] Research Article
The [ PSI + ] Prion Exists as a Dynamic Cloud of Variants[ PSI + ] Prion은 다양한 변종 클라우드로 존재합니다.Research Article Published on 2013-01-312022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] allele alleles amyloid appear array Author Cell clones cloud conditions conformation different dominant dynamic effective Efficiency Evidence explain expressing growth infectious isolate mitotic growth MOST passage Phenotypes Polymer polymorph prion progeny Protein protein sequence PSI related Saccharomyces cerevisiae segregation sequence Spectrum Spread strain Structure structures subunit Sup35p Support three group three groups translation Transmissibility Transmission transmission efficiency transmission pattern variant variants yeast [DOI] 10.1371/journal.pgen.1003257 PMC 바로가기 [Article Type] Research Article
Dynamics of Salmonella infection of macrophages at the single cell level단일 세포 수준에서의 살모넬라 감염의 역학Article Published on 2012-10-072024-07-31 Journal: Journal of the Royal Society Interface [Category] 살모넬라증, [키워드] dynamic Holling's type II infection rate Macrophage Salmonella [DOI] 10.1098/rsif.2012.0163 PMC 바로가기
Dynamic Innate Immune Responses of Human Bronchial Epithelial Cells to Severe Acute Respiratory Syndrome-Associated Coronavirus InfectionResearch Article Published on 2010-01-152022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] 2B4 cell 2B4 cells Activation aggravate antiviral genes antiviral signaling bronchial bronchial epithelial cell calu-3 cells cellular cloned complementary complex coronavirus detected detrimental dynamic epithelial epithelial cell line event expression found functional growth highlight Host Human identify IFN-stimulated gene IFN-β IFN-λ Immune-mediated Infected Inflammatory cytokine Inflammatory mediators Inflammatory responses Innate interferon interferon regulatory factor ISGs limit lung epithelial cell Lungs nuclear pathology post infection Protein Replication respiratory response resulting SARS pathogenesis SARS-CoV SARS-CoV infection secreting severe Signaling Support target these cell triggered [DOI] 10.1371/journal.pone.0008729 PMC 바로가기 [Article Type] Research Article
Dynamic changes of serum SARS-Coronavirus IgG, pulmonary function and radiography in patients recovering from SARS after hospital dischargeResearch Published on 2005-01-082022-10-28 Journal: Respiratory Research [Category] Coronavirus, [키워드] acute respiratory syndrome addition Avascular necrosis of femoral head Beijing change changes changes in chest X-ray China Chinese clinically Computerized tomography detected diagnosed diffusion discharge dynamic evaluate examined exhibited fibrosis finding Follow-up found hospital hospital discharge Hospitalized HRCT IgG IgG antibody incidence included individual joint lack lung Lung fibrosis Lung function magnetic resonance imaging MRI Necrosis objective Pain Patient patients positive predicted pulmonary fibrosis Pulmonary function receiving SARS Coronavirus SARS patient SARS-CoV SARS-CoV IgG antibody serum Serum level Severe acute respiratory syndrome (SARS) significantly subject subjects tested transfer were given [DOI] 10.1186/1465-9921-6-5 PMC 바로가기 [Article Type] Research