Extracellular
[용어속성] Term
Transferrin receptor 1 levels at the cell surface influence the susceptibility of newborn piglets to PEDV infection
Research Article
[키워드] activate
Ammonium
antibody
Caco-2
caused
Cell
Clustering
deficiency
epidemic diarrhea
expression
Extracellular
HEK 293T
impair
in vitro
in vivo
infect
Infection
infections
inhibited
interact
intestinal
intestinal epithelial cell
intestinal epithelial cells
iron accumulation
iron deficiency
mechanism
Newborn
Older
over-expressed
PEDV
Phosphorylation
promote
provide
receptor
reduce
reveal
S1 protein
susceptibility
susceptible
therapy
These data
tissue
Transferrin
Treatment
tyrosine
virus
was increased
[DOI] 10.1371/journal.ppat.1008682 PMC 바로가기 [Article Type] Research Article
[DOI] 10.1371/journal.ppat.1008682 PMC 바로가기 [Article Type] Research Article
Circulating circRNA predicting the occurrence of hepatocellular carcinoma in patients with HBV infection
Original Article
[키워드] AFP
Biomarker
chronic hepatitis
circRNA
Extracellular
[DOI] 10.1111/jcmm.15635 PMC 바로가기 [Article Type] Original Article
[DOI] 10.1111/jcmm.15635 PMC 바로가기 [Article Type] Original Article
Viral Evasion of the Complement System and Its Importance for Vaccines and Therapeutics
Immunology
[키워드] adaptive
Adaptive immune response
Antiviral effect
antivirals
chemotaxis
complement
complement system
COVID-19 pandemic
dengue virus
disease
disease symptoms
dysregulation
Effective vaccines
Effects
ENhance
evade
exacerbate
Extracellular
Factor
functions
Genetic
host response
Immunity
immunology
Importance
induce
Inflammatory responses
Innate immunity
Interaction
mechanism
microorganisms
neutralization
Nipah virus
occur
outcome
Pathogenesis
Pathogens
pathway
PROTECT
Regulation
Research
respond
Stage
System
Therapeutics
this system
Vaccines
viral infection
viral infections
viral infectivity
Virology
virus
viruses
West Nile Virus
[DOI] 10.3389/fimmu.2020.01450 PMC 바로가기 [Article Type] Immunology
[DOI] 10.3389/fimmu.2020.01450 PMC 바로가기 [Article Type] Immunology
The membrane protein ANKH is crucial for bone mechanical performance by mediating cellular export of citrate and ATP
막 단백질 ANKH는 구연산염과 ATP의 세포 내보내기를 매개하여 뼈의 기계적 성능에 중요합니다
Research Article
[키워드] absence
Affect
affecting
ANKH
ankylosis
Arthritis
ATP
blood vessel
blood vessels
bone
bone matrix
Brain
calcification
cells
cellular
citrate
Concentration
contribute
Critical
cultured cell
cultured cells
cytosol
disposition
ENPP1
excretion
expected
explain
Extracellular
extracellular ATP
functional
hands
homeostasis
Human
hydroxyapatite
in urine
in vivo
inhibitor
joint
joints
membrane protein
metabolite
metabolomics
mice
muscle
Mutation
nucleoside
nucleoside triphosphates
pathway
Patient
phenotype
phosphodiesterase
plasma
Prevent
provide
Pyrophosphatase
Pyrophosphate
reduced
released
spine
thought
tissues
underlie
undetectable
Urine
wild type
[DOI] 10.1371/journal.pgen.1008884 PMC 바로가기 [Article Type] Research Article
[DOI] 10.1371/journal.pgen.1008884 PMC 바로가기 [Article Type] Research Article
Caspase1/11 signaling affects muscle regeneration and recovery following ischemia, and can be modulated by chloroquine
Research Article
[키워드] Affect
affected
ATP
autophagy
cardiovascular disease
caspase-1
caused
Cell
Chloroquine
cleaved
consolidation
COVID-19
derivatives
disease
Doppler
Effect
enzyme
exacerbated
expected
expression
Extracellular
fibrosis
Glycolysis
immunofluorescence
increase
Inflammasome
Inflammatory
inhibitor
Ischemia
Ischemic muscle
isoform
Laser
Liver injury
Lysosomal inhibition
mice
Microscopy
modulated
muscle
myocytes
oxidative phosphorylation
oxygen
patients with comorbidity
Perfusion
Protective
Protein
reduced
reductions in
Result
Signaling
significant increases in
tibialis anterior
treated
viral disease
was measured
[DOI] 10.1186/s10020-020-00190-2 PMC 바로가기 [Article Type] Research Article
[DOI] 10.1186/s10020-020-00190-2 PMC 바로가기 [Article Type] Research Article
Vimentin as a Multifaceted Player and Potential Therapeutic Target in Viral Infections
Review
[키워드] addition
anti-vimentin autoantibodies
antibody
antiviral strategy
appear
approach
autoantigen
Autoimmune disease
Bacterial
Cell
cell activation
cell surface
cell surface vimentin
cell types
cellular processe
cellular receptor
complex
contribute
coronavirus
cytoplasmic
cytoskeletal
Encephalitis
Extracellular
filament protein
functions
immune response
implication
in viral
Infection
Inflammation
Injury
Interaction
interfere
intermediate filaments
Migration
modulate
Occurrence
oxidative damage
Pathogens
pathophysiological
pathophysiology
Perspective
Phosphorylation
posttranslational modifications
Potential
Proinflammatory cytokine
Protein
receptor
required
SARS-CoV
secreted
shown
target
tissue damage
tissue damage and repair
vimentin
vimentin–pathogen interactions
viral pathogenesis
viral pathogens
virus
viruses
[DOI] 10.3390/ijms21134675 PMC 바로가기 [Article Type] Review
[DOI] 10.3390/ijms21134675 PMC 바로가기 [Article Type] Review
Putative Roles for Peptidylarginine Deiminases in COVID-19
Article
[키워드] A549 cell lines
A549 cells
addition
alveolar
alveolar cell
Analysis
Anti-viral
autoimmune conditions
BioProject
biopsy
bowel
cells
changes
Comorbidities
conserved
contributing to
COVID-19
COVID-19 symptoms
disease
downregulated
elevated
enzyme
epithelial
expression
Extracellular
extracellular vesicles (EVs)
fat
Health
healthy volunteer
highlight
Immunity
implicated
in silico analysis
in viral
in-host
infected cells
Infection
infections
Inflammatory
inflammatory pathways
isozyme
KEGG
kidney
Kidney injury
lung
lung epithelial
lung tissue
mock cells
modulation
mRNA
mRNA level
NETosis
NHBE
organ
other tissue
PADI1
PADI2
PADI3
PADI4
PADI6
Pathway analysis
Patient
peptidylarginine deiminases (PADs)
phylogenetically
Protein
protein deimination
reduced
Regulation
response
responses
reveal
role
SARS-CoV-2
SARS-COV-2 infection
SARS-CoV-2-infected patients
stroke
therapeutic target
tissue
tissue biopsies
Transcriptome
utilised
Variability
Variation
Vascular
Vesicle
viral infections
[DOI] 10.3390/ijms21134662 PMC 바로가기 [Article Type] Article
[DOI] 10.3390/ijms21134662 PMC 바로가기 [Article Type] Article
Mesenchymal stem cell derived extracellular vesicles: promising immunomodulators against autoimmune, autoinflammatory disorders and SARS-CoV-2 infection
Article
[키워드] Activation
adaptive
affecting
Autoimmune
Autoimmunity
being
binding
Cell
cell membrane
Characteristics
clinical setting
clinical study
component
COVID-19
Critical
Cytokine storm
Cytokines
cytosolic
disorder
effective
EVs
exceptional
Exosome
Exosomes
Extensive
Extracellular
extracellular vesicle
Extracellular vesicles
Factor
function
Growth factors
immune
immune cells
Immunological disorders
immunomodulator
Inflammation
inflammatory disease
Inflammatory response
inhibiting
Intercellular communication
investigated
lower risk
Lung pathology
membrane
mesenchymal stem cell
Mesenchymal stem cells
Microvesicles
Migration
miRNA
Mortality
mRNA
MSC
MSCs
outcome
pandemic
paracrine
parent cells
pathway
proliferation
regenerative
regulate
rejection
Research
SARS-CoV-2
SARS-COV-2 infection
secreted
secretion
target cell
tested
therapeutic agent
Therapies
therapy
tolerogenic immune response
transcription factors
Treatment
triggered
unique
variety
[DOI] 10.3906/biy-2002-79 PMC 바로가기 [Article Type] Article
[DOI] 10.3906/biy-2002-79 PMC 바로가기 [Article Type] Article
Efficacy and safety of aerosolized intra-tracheal dornase alfa administration in patients with SARS-CoV-2-induced acute respiratory distress syndrome (ARDS): a structured summary of a study protocol for a randomised controlled trial
Letter
[키워드] 1:1
24 hour
acute respiratory distress
Administered
administration
Aerogen
Aerogen Solo®
Aerosols
age
airway
alveolar
alveolar injury
anticipated
ARDS
backbone
Berlin criteria
blinded
blocker
Breastfeeding
carrier
cell-free DNA
citrullinated histones
clearance
cleave
Clinical practice
clinical trial
comparator
Compound
computer-generated
consecutive patient
control arm
coronavirus 2
coronavirus disease
COVID-19
COVID-19 patients
criteria
damage-associated molecular pattern
DAMP
DAMPs
diagnosed with COVID-19
dissemination
distal
Dornase alfa
dose
double-stranded
DSMB
Efficacy
element
eliminated
enteral nutrition
Extracellular
extracellular DNA
fibrosis
glycemic control
hospital
Hospitalized
hospitals
hyperinflammation
hypersensitivity
ICU
Inclusion
inclusion criteria
induce
Inflammation
intensive care
interim analysis
Intervention
Ireland
less
looser
lung
lung damage
Lungs
management
mechanical ventilation
mechanically ventilated patient
monitoring board
myeloperoxidase
NET
NETs
neutrophil
Neutrophil extracellular trap
Neutrophil extracellular traps
number
objective
Occurrence
Open-label
outcome
PaO
Paris
participant
Patient
patients
PEEP
performed
Pneumocytes
Primary outcome
progression
Prone position
Protective
protocol
randomisation
randomised
randomised controlled trial
Randomized
receive
recruit
recruitment
reduce
reducing
Registered
respiratory
Roche
Rothschild
Sample size
SARS-CoV-2
secretion
Sedation
Severe COVID-19 pneumonia
severe pneumonia
severity
statistical analysis
status
study group
Study protocol
Switzerland
syndrome
to define
Toxicity
tracheal
Treatment
Trial
usual care
Ventilation
vibrating mesh nebulizer
Volume
website
[DOI] 10.1186/s13063-020-04488-8 PMC 바로가기 [Article Type] Letter
[DOI] 10.1186/s13063-020-04488-8 PMC 바로가기 [Article Type] Letter