Interleukin-6 level is an independent predictor of right ventricular systolic dysfunction in patients hospitalized with COVID-19Observational Study Published on 2021-08-012022-10-05 Journal: Anatolian journal of cardiology [Category] 임상, [키워드] Activation All the patient Analysis can be used Chest Computerized tomography consecutive patient coronavirus disease COVID-19 Deterioration Doppler dysfunction elevated exclusion criteria functions Hospitalized IL-6 IL-6 level impairment independent Infection Inflammatory Laboratory test mechanism Mild Moderate COVID-19 Myocardial parameter Pathogenesis Patient patients hospitalized predict predicted Proinflammatory cytokine RV systolic function significant level significantly higher significantly lower tissue TTE two groups underlie ventricular with COVID-19 [DOI] 10.5152/AnatolJCardiol.2021.24946 PMC 바로가기 [Article Type] Observational Study
Immunological mechanisms of vaccine-induced protection against COVID-19 in humans인간에서 COVID-19에 대한 백신 유도 보호의 면역학적 메커니즘Review Published on 2021-08-012022-09-11 Journal: Nature reviews. Immunology [Category] MERS, SARS, 변종, 임상, 진단, 치료기술, [키워드] Adenovirus adenovirus vaccine antibody approval approved Cell COVID-19 COVID-19 vaccine detectable dose driving Effector mechanism Efficacy elicit functions Human identifying immune immune responses inactivated innate immune mechanism mechanisms moderate MOST mRNA mRNA vaccine NAb NAbs Neutralizing antibodies neutralizing antibody phase III trial Phase III trials Protein subunit reported response SARS-CoV-2 spike protein single dose Spike protein T cell T cell responses T cells T helper the SARS-CoV-2 These data Vaccine development Vaccines virus Virus neutralization [DOI] 10.1038/s41577-021-00578-z PMC 바로가기 [Article Type] Review
Selection and application of biological safety cabinets in diagnostic and research laboratories with special emphasis on COVID-19COVID-19에 특히 중점을 둔 진단 및 연구 실험실의 생물학적 안전 캐비닛 선택 및 적용Review Published on 2021-08-012022-09-12 Journal: The Review of Scientific Instruments [Category] MERS, SARS, 진단, [키워드] adherence biological safety cabinet biosafety coronavirus disease COVID-19 diagnostic equipment function functions global public health global public health emergency handling Health Organization imperative infectious agents information International knowledge Laboratory mandatory National pandemic pathogen Pathogens product PROTECT Research respiratory risk Risk assessment SARS-CoV-2 scanty Selection Severe acute respiratory syndrome user World Health Organization [DOI] 10.1063/5.0047716 PMC 바로가기 [Article Type] Review
Acute symptomatic seizures and COVID-19: Hospital-based studyObservational Study Published on 2021-08-012022-10-05 Journal: Epilepsy research [Category] SARS, 임상, [키워드] Aswan Blood Brain C-reactive protein cerebrovascular Cerebrovascular stroke CNS Coagulation complete blood picture Computed tomography COVID COVID-19 COVID-19 infection diagnosed Encephalitis epilepsy explain Frequency functions Hemorrhagic hospital laboratory investigation liver magnetic resonance imaging majority material MRI Occurrence pathology pathophysiological mechanisms Patient patients patients with COVID-19 renal Seizure Seizures serum stroke suffered symptomatic university with COVID-19 [DOI] 10.1016/j.eplepsyres.2021.106650 PMC 바로가기 [Article Type] Observational Study
Mesenchymal Stem Cell-Derived Exosomes: Applications in Regenerative MedicineReview Published on 2021-08-012022-10-31 Journal: Cells [Category] COVID-19, [키워드] activities Angiogenesis application biological property Brain candidate cardiovascular disease cell differentiation cell surface receptors cell type cellular contribute COVID-19 Cytokines Enzymes Exosome exosome biogenesis Exosomes extracellular space Extracellular vesicles facilitate function functions Growth factors highlight immune Intercellular communication Isolation knowledge lipids Medicine Mesenchymal stem cells microRNA MicroRNAs modulation molecular multivesicular bodies nucleic acids paracrine plasma membrane produced proliferation Proteins regenerative regenerative medicine released secreted Signaling stability STEM Stress therapy tissue tissue regeneration Toxicity transcription factors Traumatic brain injury Vesicle wound healing [DOI] 10.3390/cells10081959 PMC 바로가기 [Article Type] Review
COVID-19 vaccine capacity: Challenges and mitigation – The DCVMN perspectiveShort communication Published on 2021-08-012022-10-05 Journal: Vaccine [Category] SARS, 임상, [키워드] challenge clinical trials country COVID-19 COVID-19 vaccine COVID-19 vaccines Developing function functions indicated network organization organizations Perspective producing RNA Support Technology transfer transfer Vaccine Vaccine supply variety [DOI] 10.1016/j.vaccine.2021.07.007 [Article Type] Short communication
Deep insight: Convolutional neural network and its applications for COVID-19 prognosisReview article Published on 2021-08-012022-10-05 Journal: Biomedical Signal Processing and Control [Category] 유전자 메커니즘, 치료기술, [키워드] Activation adopted applicability Applications challenges characterized China CNN Community Contact tracing contagious Convolutional neural network coronavirus disease country COVID-19 COVID-19 pandemic COVID-19 prognosis curtail deaths deep deep learning develop effective Epidemics Evidence functions globe help highlight Human limitations manual intervention medication Mortality notable pandemic pathogenic Performance metrics positive Practitioner Prognosis Radiographic recognize Research researcher respiratory viral infection Result SARS-CoV-2 shown significantly Spread Treatment variants World Health Organisation Wuhan [DOI] 10.1016/j.bspc.2021.102814 [Article Type] Review article
Inverse Association Between the Mediterranean Diet and COVID-19 Risk in Lebanon: A Case-Control StudyNutrition Published on 2021-07-302022-10-31 Journal: Frontiers in Nutrition [Category] COVID-19, [키워드] absence alcohol alleviate Analysis association average case control study caused collected containment measures control group correlated COVID-19 COVID-19 infection diet dietary habit dietary intake dietary patterns disease Effects favor food Frequency functions Gender group Health Health status healthy immune response immune system Immunity impacted Inflammation information inverse lack Lebanon less Mediterranean diet nutrition Occurrence outcomes pandemic participant public health crisis questionnaire Research semi-quantitative significant difference Sociodemographic characteristics Support Western diet [DOI] 10.3389/fnut.2021.707359 PMC 바로가기 [Article Type] Nutrition
Combination of a Sindbis-SARS-CoV-2 Spike Vaccine and αOX40 Antibody Elicits Protective Immunity Against SARS-CoV-2 Induced Disease and Potentiates Long-Term SARS-CoV-2-Specific Humoral and T-Cell Immunitysindbis-sars-cov-2 스파이크 백신과 αOX40 항체의 조합은 SARS-COV-2 유도 질환에 대한 보호 면역을 유도하고 장기 SARS-COV-2- 특이 적 유머 및 T- 세포 면역을 강화시킨다.Immunology Published on 2021-07-292022-08-31 Journal: Frontiers in Immunology [Category] SARS, 바이오마커, 변종, 진단, [키워드] αOX40 activated T cells Against alphavirus vaccine Analysis antibody approach can be used caused cellular coronavirus coronavirus SARS-CoV-2 COVID-19 pandemic COVID19 develop dose effective effective vaccine effector memory effort elicit elicited expressing functions generate hACE2 human ACE2 receptor immune protection immune response immunization immunize Immunophenotyping immunostimulatory induced Infection infection assay inhibit long-lasting neutralizing antibodies long-lasting neutralizing antibody lung tissue mice MOST mounted Neutralizing antibodies OX40 Pathogens platform profiles protective immunity Protein binding provided reprogramming RNA robust SARS-CoV-2 SARS-CoV-2 immunity SARS-CoV-2 spike protein SARS-CoV-2 vaccine sera Sindbis virus vaccine spike Spike protein synergistic combination SARS-CoV-2 vaccine strategy T cell T cells T-cell Response T-cell responses the SARS-CoV-2 the vaccine Transcriptome transgenic mice Vaccine vaccine platform variant variants [DOI] 10.3389/fimmu.2021.719077 PMC 바로가기 [Article Type] Immunology
N6-methyladenosine methyltransferases: functions, regulation, and clinical potentialReview Published on 2021-07-272022-10-29 Journal: Journal of Hematology & Oncology [Category] COVID-19, [키워드] Affect approach Cancer Chemotherapy complexes Drug discovery function functions highlight Immunotherapy m6A m6A methyltransferase methyltransferase Modification N6-methyladenosine Noncoding RNAs pathway Proteins Radiotherapy Regulation reported RNA RNAs stability targeted therapy therapy Therapy resistance Transcriptome translation widespread [DOI] 10.1186/s13045-021-01129-8 PMC 바로가기 [Article Type] Review