Single-cell multiomics revealed the dynamics of antigen presentation, immune response and T cell activation in the COVID-19 positive and recovered individualsArticle Published on 2022-12-022023-07-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), [키워드] Bayesian network model COVID-19 immune response recovered COVID-19 individuals single cell multi-omics. T-cell activation [DOI] 10.3389/fimmu.2022.1034159 PMC 바로가기
Estimating decay curves of neutralizing antibodies to SARS-CoV-2 infectionArticle Published on 2022-12-022023-07-09 Journal: Mathematical medicine and biology : a journal of t [Category] COVID19(2023년), [키워드] COVID-19 immune response Immunity model. [DOI] 10.1093/imammb/dqac008
Identification of circulating microRNA profiles associated with pulmonary function and radiologic features in survivors of SARS-CoV-2-induced ARDSSARS-CoV-2에 의해 유발된 ARDS 생존자의 폐 기능 및 방사선학적 특징과 관련된 순환 microRNA 프로파일 식별Article Published on 2022-12-012022-09-11 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 유전자 메커니즘, 임상, [키워드] acute respiratory distress syndrome Anti-inflammatory ARDS association carbon monoxide cell death Chest computed tomography circulating Coagulation Complete composed Computed tomography conducted correlated COVID-19 develop diffusing diffusing capacity distress enrichment analyses enrichment analysis evaluated Evidence evidence of feature Features Follow-up Gene ontology genomes hospital discharge hypoxia identification immune response infected patient infected patients KEGG KEGG pathway Kyoto lung Lung function median microRNA miR-126 miR-146 miR-146a-5p miR-21 miR-9 miRNA miRNA profiles miRNA profiling miRNA signature molecular molecular mechanism molecular mechanisms Pathogenesis pathophysiology pathway Patient patients predicted profile provided Pulmonary function radiologic radiological feature radiological features Random forest respiratory distress Respiratory distress syndrome RT-qPCR SARS-COV-2 infection secondary to Sequelae severe COVID-19 severity survivor to define Total severity score Trial registration TSS vascularization viral infection was performed was used [DOI] 10.1080/22221751.2022.2081615 PMC 바로가기 [Article Type] Article
Immunouniverse of SARS-CoV-2Review Published on 2022-12-012023-07-09 Journal: Immunological medicine [Category] COVID19(2023년), [키워드] Cytokines Hypercoagulation hyperinflammation immune response [DOI] 10.1080/25785826.2022.2066251 [Article Type] Review
Serosurvey in SARS-CoV-2 inactivated vaccine-elicited neutralizing antibodies against authentic SARS-CoV-2 and its viral variantsArticle Published on 2022-12-012022-11-15 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] acute respiratory syndrome Administered Antibody neutralization BBIBP-CorV Beta booster vaccination circulating CoronaVac coronavirus Delta Eta Gamma humoral immune response immune immune response inactivated Inactivated vaccine individual Lineage lineages morbidity and mortality Mutation neutralization neutralization titer neutralize neutralized Neutralizing Neutralizing antibodies neutralizing antibody Neutralizing antibody response omicron reduce SARS-CoV-2 SARS-CoV-2 variant second vaccination serum sample significantly lower the SARS-CoV-2 vaccine dose variant viral variant Viral variants virus virus strain viruses wild-type [DOI] 10.1002/jmv.28049 PMC 바로가기
Transcriptomic analysis of the innate immune signatures of a SARS-CoV-2 protein subunit vaccine ZF2001 and an mRNA vaccine RRVSARS-CoV-2 단백질 소단위 백신 ZF2001 및 mRNA 백신 RRV의 타고난 면역 특징의 전사체 분석Article Published on 2022-12-012022-09-11 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 유전자 메커니즘, 진단, [키워드] Activation Analysis Anti-viral antibody approach binding CD74 Cell comparable COVID-19 cytokine Cytokines early response elicited expression level expression of gene framework Gene Expression Genes immune response immune responses immunization innate immune innate immune response Innate immunity involved mapped MHC class mRNA mRNA vaccine neutralization Neutralization antibody Pattern recognition pattern recognition receptor Pattern recognition receptors post vaccination Protein subunit protein subunit vaccine PRRs RNA degradation robust SARS-CoV-2 SARS-CoV-2 protein subunit Subunit vaccine Tap1 titre titres Transcription transcriptional Transcriptome transcriptome sequencing transcriptomic transduction Vaccine ZF2001 [DOI] 10.1080/22221751.2022.2059404 PMC 바로가기 [Article Type] Article
Effects of boosted mRNA and adenoviral-vectored vaccines on immune responses to omicron BA.1 and BA.2 following the heterologous CoronaVac/AZD1222 vaccinationArticle Published on 2022-12-012022-11-15 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] acute respiratory syndrome addition adenoviral-vectored vaccine antibody AZD1222 binding antibody BNT162b2 booster booster vaccination Booster vaccine comparable Complete coronavirus Coronavirus 2019 COVID-19 demonstrated develop dose Effect enrolled enzyme-linked immunosorbent Heterologous highest immune evasion immune response immunogenicity analysis individual induce interferon-γ Messenger RNA Mild moderate mRNA mRNA vaccine mRNA-1273 mutations NAb titer NAbs neutralization neutralize Neutralizing Neutralizing activity neutralizing antibody observé omicron Omicron variant overcome participant raise receive receiving reduction response Serious Adverse Events significant increase Spike protein T-cell activation T-cell Response T-cell responses vaccination Vaccine waning immunity was recorded were measured [DOI] 10.1002/jmv.28044 PMC 바로가기
Vitamin D deficiency in critically ill COVID-19 ARDS patientsArticle Published on 2022-12-012023-07-06 Journal: Clinical nutrition (Edinburgh, Scotland) [Category] COVID19(2023년), [키워드] acute respiratory distress syndrome Critical care immune response nutrient supplementation Vitamin D [DOI] 10.1016/j.clnu.2021.03.001 PMC 바로가기
Lycopene: a therapeutic strategy against coronavirus disease 19 (COVID- 19)Review Published on 2022-12-012023-07-10 Journal: Inflammopharmacology [Category] COVID19(2023년), [키워드] COVID-19 immune response Lycopene oxidative stress pro-inflammatory cytokine [DOI] 10.1007/s10787-022-01061-4 PMC 바로가기 [Article Type] Review
Ultrarapid and ultrasensitive detection of SARS-CoV-2 antibodies in COVID-19 patients via a 3D-printed nanomaterial-based biosensing platformArticle Published on 2022-12-012022-11-15 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] 3D biosensor 3D printing Additive manufacturing antibody Antibody detection coated with Concentration COVID-19 COVID-19 antibodies COVID-19 patient COVID-19 patients Critical detected antibody disease domain Efficacy Epidemics Epidemiology evaluate Gold nanoparticle Graphene oxide human plasma samples immune response Immunity Infection Interaction manuscript nucleocapsid Outbreaks Patient patients without COVID-19 platform Quantitative Rapid rapid antibody detection. rapid antibody test RBD reported SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 antigens serological Spike protein the antibodies the N protein vaccination Vaccine Viral protein were used [DOI] 10.1002/jmv.28075 PMC 바로가기