Messenger RNA – Page 21 – Communicable Diseases Research

Safety of the BNT162b2 mRNA Covid-19 Vaccine in a Nationwide Setting

BNT162b2 mRNA 코로나19 백신의 전국적 안전성

Original Article

Published on 2021-08-252022-11-01
Journal: The New England Journal of Medicine [Category] COVID-19, Fulltext, MERS, 대상포진, 두창, 수두,

Association Between BNT162b2 Vaccination and Incidence of SARS-CoV-2 Infection in Pregnant Women

Observational Study

Published on 2021-08-242022-10-05
Journal: JAMA [Category] 임상,

[키워드] 1:1 95% CI absolute difference adjusted hazard ratio adverse event age association BNT162b2 BNT162b2 mRNA vaccination BNT162b2 mRNA vaccine Care Cohort comparability defined Effectiveness exposure first dose Follow-up groups hazard headache Health immunization Infection Influenza interquartile range maintain median Messenger RNA mRNA mRNA vaccine of BNT162b2 outcome Pain Pfizer-BioNTech phase 3 trial polymerase chain Pregnancy pregnant women Primary outcome reported reported symptom representing retrospective cohort study risk SARS-CoV-2 SARS-COV-2 infection significantly lower symptomatic vaccination Vaccine vaccine dose weakness were excluded women
[DOI] 10.1001/jama.2021.11035 PMC 바로가기 [Article Type] Observational Study

The Post-Acute Phase of SARS-CoV-2 Infection in Two Macaque Species Is Associated with Signs of Ongoing Virus Replication and Pathology in Pulmonary and Extrapulmonary Tissues

두 개의 원숭이 종에서 SARS-COV-2 감염의 급성기 후에는 폐 및 외부 조직에서 진행중인 바이러스 복제 및 병리의 징후와 관련이 있습니다.

Article

Published on 2021-08-232022-09-01
Journal: Viruses [Category] MERS, SARS, 진단, 치료기술,

[키워드] activated acute phase animal models Computed tomography Conjunctiva consequence COVID-19 cynomolgus macaque cynomolgus macaques detectable Extrapulmonary extrapulmonary tissue feces heart histological Histopathology humans immune activation Infection investigated lesion lung lung tissue Lungs Lymph node lymph nodes macaque macaques Messenger RNA necropsy NHPs non-human primates nose nose and throat phase positron emission Positron emission tomography pulmonary pulmonary lesion pulmonary lesions respiratory respiratory tract rhesus salivary salivary gland SARS-CoV-2 SARS-COV-2 infection SIGN Specy tissue sample tissue samples tomography tracheobronchial tracheobronchial lymph nodes Viral Viral RNA virus replication
[DOI] 10.3390/v13081673 PMC 바로가기 [Article Type] Article

Efficacy of the BNT162b2 mRNA COVID-19 vaccine in patients with B-cell non-Hodgkin lymphoma

Research article

Published on 2021-08-132022-10-05
Journal: Blood advances [Category] SARS, 변종,

Antibody responses after a single dose of ChAdOx1 nCoV-19 vaccine in healthcare workers previously infected with SARS-CoV-2

이전에 SARS-CoV-2에 감염된 의료 종사자의 ChAdOx1 nCoV-19 백신 1회 투여 후 항체 반응

Research paper

Published on 2021-08-122022-09-11
Journal: EBioMedicine [Category] MERS, SARS, 변종, 진단,

[키워드] (ChAdOx1 nCoV-19 Adenovirus-vectored vaccine Administered antibody Antibody Response blocking antibodies BNT162b2 BNT162b2 vaccine booster ChAdOx1 ChAdOx1 nCoV-19 ChAdOx1 nCoV-19 vaccine contributed Delta dose effective expressing finding funding healthcare worker immune immune response immune responses individual infected with SARS-CoV-2 less Lineage Messenger RNA mild SARS-CoV-2 infection mRNA mRNA vaccine naïve Neutralizing antibodies neutralizing antibody Neutralizing antibody response of BNT162b2 participant post infection Post-vaccine Preexisting immunity Prior infection provide RBD-ACE2 RBD-specific IgG receiving recent regimen robust SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike protein serological response single dose Spike protein Support the SARS-CoV-2 two-dose regimen vaccination Vaccine variants variants of concern vectored vaccine wild type
[DOI] 10.1016/j.ebiom.2021.103523 PMC 바로가기 [Article Type] Research paper

Physiologic Response to the Pfizer-BioNTech COVID-19 Vaccine Measured Using Wearable Devices: Prospective Observational Study

Original Paper

Published on 2021-08-042022-10-30
Journal: JMIR Formative Research [Category] COVID-19,

[키워드] administration age Antibody Response baseline Biomarker changes in Cohort COVID-19 COVID-19 vaccination COVID-19 vaccine COVID-19 vaccines decrease deep sleep determine dose elicit Evidence female Future greater change healthy heart rate heart rate variability HRV immune Increased individual Inflammatory initial Local Messenger RNA MONITOR monitoring objective outcome participant Pfizer-BioNTech Physiologic physiological post vaccination Primary outcome Prophylactic Prospective prospective observational study protective immune response raise Registration REM sleep remote physiologic monitoring respiratory respiratory rate response Result Sample size secondary significant changes in Sleep subsequent systemic reactogenicity the vaccine utility vaccination Vaccine vaccine dose vaccine doses vaccine response vaccine responses Variability was collected was increased wearable wearable devices
[DOI] 10.2196/28568 PMC 바로가기 [Article Type] Original Paper

Positive aspects of the mRNA platform for SARS-CoV-2 vaccines

SARS-CoV-2 백신을 위한 mRNA 플랫폼의 긍정적인 측면

Article

Published on 2021-08-032022-09-11
Journal: Human vaccines & immunotherapeutics [Category] SARS, 유전자 메커니즘,

[키워드] assumed BNT162b1 causative agent clinical trial clinical trials coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 mRNA vaccine COVID-19 mRNA vaccines COVID-19 vaccines develop effective Effective vaccines Efficacy host genome humans imperative individual lack mechanism mechanism of action media Messenger RNA misinformation modify mRNA mRNA platform mRNA vaccine mRNA-1273 mRNA-based COVID-19 vaccine offer Pfizer raised receiving Safe SARS-CoV-2 SARS-CoV-2 vaccine skepticism skepticism. social media Strains vaccination vaccination against COVID-19 Vaccine Vaccine hesitancy vaccine platform
[DOI] 10.1080/21645515.2021.1900713 PMC 바로가기 [Article Type] Article

Frequency of positive anti-PF4/polyanion antibody tests after COVID-19 vaccination with ChAdOx1 nCoV-19 and BNT162b2

ChAdOx1 nCoV-19 및 BNT162b2로 COVID-19 백신 접종 후 항-PF4/다음이온 항체 검사 양성 빈도

Article

Published on 2021-07-292022-09-12
Journal: Blood [Category] 진단,

Immunogenicity and reactogenicity of heterologous ChAdOx1 nCoV-19/mRNA vaccination

Brief Communication

Published on 2021-07-262022-10-29
Journal: Nature Medicine [Category] COVID-19, Fulltext, SARS,

Humoral immune responses during SARS-CoV-2 mRNA vaccine administration in seropositive and seronegative individuals

혈청 양성 및 혈청 형성 개인에서 SARS-CoV-2 mRNA 백신 투여 동안 체액 면역 반응

Research Article

Published on 2021-07-262022-09-01
Journal: BMC Medicine [Category] SARS, 진단,

[키워드] administration antibody antibody level antibody levels Antibody Response Antibody responses Antibody titers approved binding Binding assays BNT162b2 caused comparable coronavirus disease Coronavirus disease 2019 COVID-19 demonstrated dose doses Efficacy epitope Epitopes first vaccination global pandemic guide had no high resolution humoral immune responses IgA IgG IgM antibody immune immune response immune responses immunization immunodominant individual Infection mapped Messenger RNA mRNA mRNA vaccine peptide peptides Pfizer-BioNTech protein antigen regimens Result S1 and S2 SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 neutralizing antibody SARS-CoV-2 spike SARS-CoV-2 spike protein SARS-CoV-2 vaccine SARS-CoV-2 viral SARS-CoV-2 virus seronegative seropositive seropositive individual seropositive individuals significantly higher single dose specificity Spike protein subunit supplementary material Support the antibody response the SARS-CoV-2 the SARS-CoV-2 virus USA vaccination Vaccine Viral viral infection while
[DOI] 10.1186/s12916-021-02055-9 PMC 바로가기 [Article Type] Research Article