Lack of antibodies against seasonal coronavirus OC43 nucleocapsid protein identifies patients at risk of critical COVID-19계절성 코로나바이러스 OC43 뉴클레오캡시드 단백질에 대한 항체 부족으로 심각한 COVID-19 위험에 처한 환자 식별Multicenter Study Published on 2021-06-012022-09-11 Journal: Journal of Clinical Virology [Category] MERS, SARS, 진단, 치료법, [키워드] adjusted adjusted odds ratio age Analysis analyzed antibody AOR benefit BMI Care conducted coronavirus Course COVID-19 COVID-19 patient Critical Critical disease disease examined females France Germany HCoV HCoV 229E HKU1 human coronavirus human coronaviruses ICU identify IgG antibodies IgG antibody immunoblot increased risk individual Infection Inpatient majority Male sex males median age Mild Mild disease morbidity and mortality Multivariate analysis NL63 nucleocapsid protein OC43 Patient plasma sample PROTECT risk Risk assessment risk factor risk stratification SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections seasonal seasonal coronavirus serostatus serum Sex significantly lower specific antibodies symptom onset tested vaccination [DOI] 10.1016/j.jcv.2021.104847 PMC 바로가기 [Article Type] Multicenter Study
Pulmonary long-term consequences of COVID-19 infections after hospital discharge퇴원 후 COVID-19 감염의 폐 장기 결과Article Published on 2021-06-012022-09-11 Journal: Clinical microbiology and infection : the official [Category] MERS, SARS, 바이오마커, [키워드] 6-minute walk test 6MWT 95%CI abnormality acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Adhesion Molecule Biomarker Biomarkers carbon monoxide Chest computed tomography Comorbidities Computed tomography consequence coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 hospitalization COVID-19 infection diffusing diffusing capacity diffusion diffusion capacity discharge discharged patient discharged patients Effect epidemiological evaluated expiratory forced expiratory volume forced vital capacity FVC group hospital hospital discharge Hospital stay Hospitalization identify Inflammation information inhibitor inhibitors Intracellular Intracellular adhesion molecule IQR laboratory parameter Laboratory parameters laboratory-confirmed Lactate lactate dehydrogenase Limited Lung diffusion capacity Lung function matrix metalloproteinases median medical histories Multivariate analysis onset of symptom Osteoprotegerin Patient patients performed plasminogen Plasminogen activator inhibitor Proteases pulmonary Pulmonary function Pulmonary function tests Real-time PCR receptor receptors recovering from COVID-19 recruited respiratory Respiratory function Respiratory function test Respiratory function tests RT-PCR SARS-CoV-2 SARS-CoV-2-infected patient SARS-CoV-2-infected patients screened serum serum lactate severe acute respiratory syndrome Coronavirus severe disease severe SARS-CoV-2 severity Spanish Sputum sample sputum samples survivor Symptom symptom onset Tissue Inhibitor Tissue inhibitor of matrix metalloproteinases tomography virus vital capacity Volume were measured [DOI] 10.1016/j.cmi.2021.02.019 PMC 바로가기 [Article Type] Article
Perceived Stress in Dentists and Dental Students of Latin America and the Caribbean during the Mandatory Social Isolation Measures for the COVID-19 Pandemic: A Cross-Sectional StudyArticle Published on 2021-05-302022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] affected applied Care coffee conducted COVID-19 COVID-19 pandemic cross-sectional survey dental dentist dentists determine Factor Health Health Surveys Latin America Linear regression mandatory measure mental health Multivariate analysis observé Older outcome pandemic Perceived Perceived stress Perceived Stress Scale Psychological Public question Regression model required significant variable social isolation Sociodemographic Stress student students Surveillance variables was used women [DOI] 10.3390/ijerph18115889 PMC 바로가기 [Article Type] Article
Impact of age to ferritin and neutrophil‐lymphocyte ratio as biomarkers for intensive care requirement and mortality risk in COVID‐19 patients in Makassar, Indonesia인도네시아 마카사르의 COVID-19 환자에서 집중 치료 요구 사항 및 사망 위험에 대한 바이오마커로서의 연령 대 페리틴 및 호중구-림프구 비율의 영향Original Article Published on 2021-05-272022-09-10 Journal: Physiological Reports [Category] 바이오마커, [키워드] 95% confidence interval Admission Affect affected age aging AUC AUC value Biomarker change clinical endpoint Clinical outcome clinical outcomes Combination Comorbidities Comorbidity Complete COVID‐19 COVID‐19 patient COVID‐19 patients COVID‐19 Deceased Disease progression Endpoint endpoints Factor ferritin group groups immune system immunosenescence Impact Indonesia inflammaging inflammatory parameter intensive care Makassar Mortality mortality risk Multivariate analysis neutrophil‐lymphocyte ratio NLR outcome pathophysiology Patient patients Predictive Predictive value prognostic biomarker Prognostic biomarkers retrospective cohort study risk significantly South survived was performed [DOI] 10.14814/phy2.14876 PMC 바로가기 [Article Type] Original Article
The systemic inflammatory response and clinicopathological characteristics in patients admitted to hospital with COVID-19 infection: Comparison of 2 consecutive cohortsCOVID-19 감염으로 입원한 환자의 전신 염증 반응 및 임상병리학적 특성: 연속 2개 코호트 비교Clinical Trial Published on 2021-05-272022-08-13 Journal: PLoS ONE [Category] MERS, SARS, 임상, [키워드] 30-Day mortality 4C mortality score addition Admission age albumin Analysis Characteristics Clinical outcome Cognitive impairment Cohort cohorts cohorts of patient Concentration COPD COVID-19 COVID-19 pandemic creatinine CXR delirium Electronic patient records elevated examined female frailty Gender Glucose greater hospital identify independent independent living Laboratory Lactate less male measure Mortality Multivariate analysis neutrophil NLR Older on admission Patient patient records PCR positive remained Result score serum albumin sodium systemic inflammatory response Trial registration urea with COVID-19 [DOI] 10.1371/journal.pone.0251924 PMC 바로가기 [Article Type] Clinical Trial
Acute kidney injury: Incidence, risk factors, and outcomes in severe COVID-19 patientsResearch Article Published on 2021-05-252022-10-28 Journal: PLoS ONE [Category] COVID-19, SARS, [키워드] Acute kidney injury AKI assist azithromycin treatment biochemical Blood Brazil C-reactive protein cause cellular clinical variables COVID-19 COVID-19 patient COVID-19 patients creatinine criteria CRP defined elevated evaluated Factors help Hospital admission hospital discharge hospitalized patient Hydroxychloroquine hypertension ICU Improving incidence Inflammatory intensive care KDIGO kidney leucocytes leukocyte leukocytes management marker mechanical ventilation Medicine Monocytes multisystemic disorder Multivariate analysis Neutrophil-to-lymphocyte ratio Neutrophils NLR Older age outcome Patient performed potential risk progression protocol Result Retrospective study risk Risk factors RT-PCR severe COVID-19 severe COVID-19 patient Stage therapy Univariate analysis university variable vasoactive drug vasoactive drugs was related with COVID-19 [DOI] 10.1371/journal.pone.0251048 PMC 바로가기 [Article Type] Research Article
A multi-modal data harmonisation approach for discovery of COVID-19 drug targetsArticle Published on 2021-05-242023-06-16 Journal: Briefings in Bioinformatics [Category] MERS, SARS, [키워드] COVID-19 data harmonisation Data integration machine learning Multi-omics Multivariate analysis SARS-CoV-2 [DOI] 10.1093/bib/bbab185 PMC 바로가기
Metabolic Profiling from an Asymptomatic Ferret Model of SARS-CoV-2 InfectionArticle Published on 2021-05-192022-10-30 Journal: Metabolites [Category] COVID-19, [키워드] addition Administered Analysis analyzed animal model applied Asymptomatic carbon metabolism Chromatography collected contagious COVID-19 COVID-19 infections COVID-19 research database days post-infection disease dose early diagnosis Effectiveness elevated ferret ferrets fragment Host immune response infancy Infection invasive investigated isolate Lipid Lipidomics liquid mass metabolic metabolism metabolite metabolites metabolomics methodology Mild Model monitoring morbidity and mortality Multiple Multivariate analysis nasal Nasal washes observational study oral swabs pathway enrichment Pathways performed phosphate Profiling purine Quadrupole reaction Rectal swabs respiratory Respiratory disease SARS-CoV-2 SARS-CoV-2 isolates SARS-CoV-2 RNA significant changes in Spectrometry Support Systems biology Therapies understanding utility viral shedding [DOI] 10.3390/metabo11050327 PMC 바로가기 [Article Type] Article
Knowledge, Attitudes and Perceptions of COVID-19 Vaccination among Healthcare Workers of an Inner-City Hospital in New YorkArticle Published on 2021-05-172022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] affected age approach approval Attitude Community conducted contracting the virus correlated COVID-19 COVID-19 pandemic COVID-19 vaccination demographics effective Factor Gender healthcare worker Healthcare workers high risk hospital IMPROVE information knowledge Multivariate analysis New York New York City Perception Personal protective equipment Predictive reduction in risk Risk perception significantly The United States the vaccine Vaccine Vaccine attitudes Vaccine hesitancy virus worker [DOI] 10.3390/vaccines9050516 PMC 바로가기 [Article Type] Article
SARS-CoV-2 transmission in students of public schools of Catalonia (Spain) after a month of reopeningResearch Article Published on 2021-05-122022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] 95% CI adjusted adopted association available data Community community transmission conducted Health incidence Multivariate analysis Poisson regression model public school random effect Ratio reduce reported Result retrospective cohort study Safety measure SARS-CoV-2 SARS-CoV-2 transmission School secondary school Spain the SARS-CoV-2 Transmission was performed [DOI] 10.1371/journal.pone.0251593 PMC 바로가기 [Article Type] Research Article