Deep sequencing of HBV pre-S region reveals high heterogeneity of HBV genotypes and associations of word pattern frequencies with HCCHBV pre-S 영역의 심층 시퀀싱은 HBV 유전자형의 높은 이질성과 HCC와 단어 패턴 빈도의 연관성을 보여줍니다Research Article Published on 2018-02-232022-09-06 Journal: PLoS Genetics [Category] B형 간염, Communicable Disease, [키워드] Accuracy Analysis approach approaches association AUC build calculated can be used characteristic CHB China Classifier Clustering Complication Cross-validation data set deep followed by fraction Frequency Genotype group HBV HBV infection HCC HCC patient hepatitis B Hepatitis B virus Hepatocellular carcinoma heterogeneity Hierarchical hierarchical clustering high accuracy High-throughput sequencing include independent data set individual individuals infected individual infected individuals Infection information lead liver Liver cancer Manhattan distance MDs next generation sequencing NGS predict prevalent Probability regions reveal Sanger sequencing second sequence sequences Sequencing shown significantly Support support vector machine SVM virus was obtained [DOI] 10.1371/journal.pgen.1007206 PMC 바로가기 [Article Type] Research Article
Whole genome sequence and a phylogenetic analysis of the G8P[14] group A rotavirus strain from roe deerResearch Article Published on 2017-11-252023-05-24 Journal: BMC veterinary research [Category] Fulltext, 조류인플루엔자, [키워드] deer Group A rotavirus next generation sequencing NGS Phylogenetic analysis wildlife zoonotic transmission [DOI] 10.1186/s12917-017-1280-4 PMC 바로가기 [Article Type] Research Article
Clinical course and core variability in HBV infected patients without detectable anti-HBc antibodiesArticle Published on 2017-08-012023-06-16 Journal: Journal of Clinical Virology [Category] B형 간염, [키워드] anti-HBc core antigen HBV hepatitis B Immunosuppression NGS [DOI] 10.1016/j.jcv.2017.06.001
Genome-Wide Comparison of Next-Generation Sequencing and qPCR Platforms for microRNA Profiling in SerumComparative Study Published on 2017-01-012023-06-16 Journal: Methods in molecular biology (Clifton, N.J.) [Category] B형 간염, [키워드] biofluids HBV HCV liquid biopsy microRNA miRNA Next-generation sequencing NGS plasma Platform comparison Profiling qPCR Real-time PCR serum validation [DOI] 10.1007/978-1-4939-6866-4_3 [Article Type] Comparative Study
Tunable and label-free virus enrichment for ultrasensitive virus detection using carbon nanotube arraysArticle Published on 2016-10-072023-06-03 Journal: Science Advances [Category] Fulltext, 조류인플루엔자, [키워드] carbon nanotubes enrichment field samples improved detection Influenza N-doped NGS PCR sensor virus [DOI] 10.1126/sciadv.1601026 PMC 바로가기
Pathosphere.org: pathogen detection and characterization through a web-based, open source informatics platformSoftware Published on 2015-12-292022-10-27 Journal: BMC Bioinformatics [Category] Coronavirus, [키워드] addition Analysis analyzed annotation bioinformatics Biological center Chemical Community complex coronavirus creating detect Government homology Host identify Illumina Infectious disease Ion iterative NCBI Next-generation sequencing NGS pathogen pathogen detection platform provide Result sequence sequenced Sequencing supplementary material Support tested the United State utility variety zoonotic [DOI] 10.1186/s12859-015-0840-5 PMC 바로가기 [Article Type] Software
Genetic Characterization of the Belgian Nephropathogenic Infectious Bronchitis Virus (NIBV) Reference Strain B1648Communication Published on 2015-08-072022-10-28 Journal: Viruses [Category] Coronavirus, [키워드] accessory protein Amino acid Analysis B1648 Belgium characterization chicken circulating Complete complex determinant Europe Evolution Factor full-length genome Genetic genomes Genotype Gray highest IBV identify indicated Infectious Bronchitis Virus Intensive M protein Massachusett nephropathogenic NGS nonstructural protein North Open reading frame ORF ORFs Phylogenetic analysis predicted reference reported sequence sequence homology Sequencing Spike protein strain Strains transcriptase vaccination variant virulent was determined [DOI] 10.3390/v7082827 PMC 바로가기 [Article Type] Communication
Protocol for Metagenomic Virus Detection in Clinical Specimens 1Article Published on 2015-01-012023-05-31 Journal: Emerging Infectious Diseases [Category] Fulltext, 조류인플루엔자, [키워드] Emerging infectious diseases Infectious diseases Influenza virus metagenome metagenomics Next-generation sequencing NGS random PCR Reovirus Sendai virus vaccinia virus virus detection viruses zoonoses [DOI] 10.3201/eid2101.140766 PMC 바로가기
Glycans from avian influenza virus are recognized by chicken dendritic cells and are targets for the humoral immune response in chickenArticle Published on 2013-12-012023-06-02 Journal: Molecular immunology [Category] 조류인플루엔자, [키워드] (BM)-DC (bone marrow-derived) dendritic cell Ab AIV antibody Avian influenza virus beta-propiolactone BPL C-type lectin CLR DC-SIGN Dendritic Cell-Specific Intercellular adhesion molecule-3-Grabbing Non-integrin dendritic cells Glycan-recognizing antibodies HA Haemagglutinin highly pathogenic horseradish peroxidase HP HRP IG Immunoglobulin lectins low pathogenic LP macrophage galactose-type lectin 1 macrophage mannose receptor MGL-1 MMR N-glycosylation sites NA neuraminidase NGS PAA polyacrylamide SA sialic acid [DOI] 10.1016/j.molimm.2013.06.007
Identification and Survey of a Novel Avian Coronavirus in DucksResearch Article Published on 2013-08-302022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] Analysis caused China circulating clade coronavirus CoV CoVs distribution duck Evolution IBV identification indicated infect Infectious Bronchitis Virus Infectious disease NGS novel novel virus Novel viruses performed polymerase chain positive provided Region RT-PCR sequence Sequencing subclade suggested survey the viral nucleocapsid [DOI] 10.1371/journal.pone.0072918 PMC 바로가기 [Article Type] Research Article