SARS-CoV-2 and superimposed infection by trichomonadsComment Published on 2021-03-012023-06-19 Journal: The Journal of Infection [Category] Fulltext, SARS, [키워드] COVID-19 pneumocystis pneumonia Respiratory distress syndrome SARS-CoV-2 Trichomonas infections. [DOI] 10.1016/j.jinf.2020.11.038 PMC 바로가기 [Article Type] Comment
EGCG, a Green Tea Catechin, as a Potential Therapeutic Agent for Symptomatic and Asymptomatic SARS-CoV-2 Infection증상 및 무증상 SARS-CoV-2 감염에 대한 잠재적 치료제로서의 녹차 카테킨인 EGCGReview Published on 2021-02-242022-09-10 Journal: Molecules [Category] MERS, 신약개발, 치료제, [키워드] abrogate acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 agent Analysis approved Arthritis Asymptomatic binding broad spectrum catechin catechins caused claimed contribute coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 case COVID-19 infection COVID-19 patients distress drug dysregulation Efficacy EGCG epigallocatechin epigallocatechin gallate gallate globe green immune dysregulation immunized in silico individual Inflammation Inflammatory inflammatory condition inflammatory signal inflammatory signals inhibit inhibitory initial gene interferon ISGylation knowledge morbidity Ontology Papain-like protease pathophysiology performed PLPro Potential predict protease Protein respiratory respiratory distress Respiratory distress syndrome rheumatoid arthritis SARS-CoV-2 severe acute respiratory syndrome Coronavirus similarity stimulated symptomatic syndrome tea therapeutic ubiquitination United State United States vaccination Vaccines Viral protein Viral proteins [DOI] 10.3390/molecules26051200 PMC 바로가기 [Article Type] Review
Clonal expansion and activation of tissue-resident memory-like T H 17 cells expressing GM-CSF in the lungs of patients with severe COVID-19중증 COVID-19 환자의 폐에서 GM-CSF를 발현하는 조직 상주 기억 유사 T H 17 세포의 클론 확장 및 활성화Research Article Published on 2021-02-232022-09-12 Journal: Science Immunology [Category] Fulltext, MERS, 진단, [키워드] Activation acute respiratory distress acute respiratory distress syndrome Analysis Autoimmune diseases Bacterial bacterial pneumonia BAL Blood Bronchoalveolar lavage Bronchoalveolar lavage fluid CD8 Cell cell type cells cellular characterized Clinical course clonal expansion clone Cohort cohort of patient collected contribute coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pneumonia CSF2 cytokine cytokine expression profile disease severity elevated expressing feature Generation GM-CSF helper high mortality hyperinflammation identify IL-17A IL17A Immune cell immune cell type immune cells immune response Immunopathogenesis interactome investigated involved lung lung damage Lung injury Lung pathology lung tissue Lungs Macrophage macrophages mechanism memory T cell moderate disease pathogenic Patient patients with COVID-19 Pneumonia protein level pulmonary T respiratory distress Respiratory distress syndrome serum severe coronavirus disease severe COVID-19 Severe COVID-19 pneumonia single-cell subsequent syndrome T cell T cell response T cells T helper TCR Th17 cells Therapies tissues Transcriptome Viral viral clearance viral infection [DOI] 10.1126/sciimmunol.abf6692 PMC 바로가기 [Article Type] Research Article
Prevalence of comorbidity in Chinese patients with COVID-19: systematic review and meta-analysis of risk factors중국 코로나19 환자의 동반질환 유병률: 위험인자에 대한 체계적인 검토 및 메타분석Meta-Analysis Published on 2021-02-222022-09-01 Journal: BMC Infectious Diseases [Category] MERS, 진단, [키워드] 95% CI 95%CI acute lung injury acute respiratory distress acute respiratory distress syndrome ARDS article Cancer cardiovascular disease cerebrovascular Cerebrovascular disease characterized Chinese patient Chronic kidney disease chronic liver disease Chronic Liver Diseases chronic obstructive chronic obstructive pulmonary disease CKD CLD CNKI Comorbidities Comorbidity condition COPD coronavirus disease Coronavirus disease 2019 cough COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 patients COVID-19 progression COVID-19 severity Deterioration develop diabete diabetes disease disease severity eight exhibited fatigue Fever followed by General population greater hypertension IMPROVE Infection prevention Infectious disease Kidney disease Lung injury malignancy manifestation Meta-analysis Mortality no correlation obstructive pulmonary disease outcome Patient performed Prevalence Prognosis pulmonary disease reported respiratory distress Respiratory distress syndrome Result resulting risk risk factor Risk factors searched severity subgroup supplementary material syndrome systematic review the strongest Treatment strategies treatment strategy underlying disease underlying diseases Web of Science [DOI] 10.1186/s12879-021-05915-0 PMC 바로가기 [Article Type] Meta-Analysis
Systemische Auswirkungen und klinische Aspekte der SARS-CoV-2-InfektionSchwerpunkt: COVID-19 Published on 2021-02-112022-10-28 Journal: Der Pathologe [Category] COVID-19, MERS, SARS, [키워드] ARDS Autopsie Autopsy COVID-19 form Hypertonus Ischämische Darmschädigung Ischemic bowel disease Lungenversagen material Pulmonale Thrombose pulmonary thrombosis Respiratory distress syndrome [DOI] 10.1007/s00292-021-00913-0 PMC 바로가기 [Article Type] Schwerpunkt: COVID-19
A double blinded placebo controlled comparative clinical trial to evaluate the effectiveness of Siddha medicines, Kaba Sura Kudineer (KSK) & Nilavembu Kudineer (NVK) along with standard Allopathy treatment in the management of symptomatic COVID 19 patients – a structured summary of a study protocol for a randomized controlled trial증상이 있는 COVID 19 환자의 관리에서 표준 동종 요법 치료와 함께 Siddha 의약품, Kaba Sura Kudineer(KSK) 및 Nilavembu Kudineer(NVK)의 효과를 평가하기 위한 이중 맹검 위약 대조 비교 임상 시험 - 에 대한 연구 프로토콜의 구조화된 요약 무작위 대조 시험Letter Published on 2021-02-112022-09-10 Journal: Trials [Category] MERS, 임상, [키워드] acute respiratory distress syndrome addition Adverse adverse events age age and sex appearance Arm Asymptomatic Bacterial biochemical markers blinded block calculated CAM change Chemical clinical clinical symptom Clinical symptoms clinical trial Complication complications Controlled count COVID COVID 19 COVID 19 patient CRP Ct value CTRI D-dimer Data analysis Date determine diagnose dimer dissemination drug Effect Effectiveness element eligibility eliminated enrolment evaluate exploratory ferritin food GMP group Herbal Hospital stay IL 6 IL6 incidence India Infection infiltration Inflammatory marker inflammatory markers Informed consent investigators involved Laboratory LDH literature management marker Medical Sciences Medicine Medicines Microsoft Excel moderate symptom moderate symptoms morning Night number objective outcome participant Patient patients PCR Placebo Pneumonia profile protocol randomised controlled trial randomization Randomized Randomized controlled trial Ratio recruited recruitment reduce reduction Registered Registration registry reported respiratory respiratory distress Respiratory distress syndrome risk Sample Sample size SARS-CoV-2 secondary Secondary objectives Secondary outcomes severe COVID-19 symptoms Siddha Siddha Medicine smoking SPIRIT guidelines statistician status Study protocol submission Sura symptomatic Taste tea the disease time Total Treatment Trial trial protocol Trial registration value Viral Viral load Viral pneumonia website were blinded [DOI] 10.1186/s13063-021-05041-x PMC 바로가기 [Article Type] Letter
Myocardial Injury in Severe COVID-19 Compared With Non-COVID-19 Acute Respiratory Distress SyndromeComparative Study Published on 2021-02-092023-07-12 Journal: Circulation [Category] SARS, [키워드] COVID-19 Respiratory distress syndrome troponin [DOI] 10.1161/CIRCULATIONAHA.120.050543 PMC 바로가기 [Article Type] Comparative Study
COVID-19: Auswirkungen auf Lunge und HerzArticle Published on 2021-02-092023-06-16 Journal: Der Pathologe [Category] MERS, SARS, 신종인플루엔자, [키워드] Angiogenese Angiogenesis Human influenza Humane Influenza Lungenversagen Pneumonia pneumonie Respiratory distress syndrome SARS-CoV‑2 [DOI] 10.1007/s00292-021-00918-9 PMC 바로가기
Circulating Markers of Neutrophil Extracellular Traps Are of Prognostic Value in Patients With COVID-19호중구 세포외 트랩의 순환 마커는 COVID-19 환자에서 예후 가치가 있습니다Article Published on 2021-02-012022-09-11 Journal: Arteriosclerosis, Thrombosis, and Vascular Biology [Category] MERS, 바이오마커, [키워드] acute respiratory distress acute respiratory distress syndrome association Asymptomatic Blood cells C-reactive protein cell-free DNA characterized circulating Clinical outcome Coagulation convalescent plasma coronavirus disease Coronavirus disease 2019 correlated COVID-19 COVID-19 disease COVID-19 disease severity Cytokines declined Disease progression disease severity elevated endothelial damage enrolled evaluate Evidence Extracellular extracellular traps fibrinolysis healthy controls healthy individual healthy individuals histone Hospital admission hyperinflammation immunothrombosis in healthy individual in vivo Infection Inflammation Inflammatory cytokines marker moderate moderate to severe Mortality NET NETs neutrophil Neutrophil elastase Neutrophil extracellular trap Neutrophils pathogenic mechanism pathogenic mechanisms patients with COVID-19 plasma plasma sample plasma samples Post-infection progression respiratory respiratory distress Respiratory distress syndrome Respiratory Support SARS-CoV2 severe disease syndrome target targets therapeutic intervention thrombosis thrombotic thrombotic microangiopathy TRAP value were assessed White blood cells with COVID-19 [DOI] 10.1161/ATVBAHA.120.315267 PMC 바로가기 [Article Type] Article
SARS-CoV-2 infection: molecular mechanisms of severe outcomes to suggest therapeuticsSARS-CoV-2 감염: 치료법을 제안하는 심각한 결과의 분자 메커니즘Review Published on 2021-02-012022-09-11 Journal: Expert review of proteomics [Category] MERS, 유전자 메커니즘, 진단, [키워드] acute respiratory distress acute respiratory distress syndrome acute respiratory distress syndrome. ARDS Area base pair base pairs Biomarker Biomarkers Clinical course clinical risk factor Clinical risk factors Combination COVID-19 cytokine cytokine signaling dataset datasets defined door drug endotheliopathy expert genetics Google Scholar Human Impact infect Infection literature MODS molecular molecular mechanism multiple organ dysfunction multiple organ dysfunction syndrome NCBI NETosis opens organ dysfunction syndrome outcome pathology pathway Patient patients with COVID-19 Pneumonia positive feedback positive feedback loop Precision pyroptosis respiratory distress Respiratory distress syndrome Risk factors RNA SARS-CoV-2 SARS-CoV-2 genome secondary infections severe COVID-19 SRA Support syndrome tested the SARS-CoV-2 genome therapeutic Therapeutics thrombocytopathy treat Treatment Treatment strategies treatment strategy understanding unique [DOI] 10.1080/14789450.2021.1908894 PMC 바로가기 [Article Type] Review