Decoding information on COVID–19: Ontological approach towards design possible therapeuticsReview article Published on 2020-11-272022-10-05 Journal: Informatics in Medicine Unlocked [Category] 신약개발, 치료제, [키워드] “cytokine storm” accelerate Antiviral approach caused Characteristics Comorbidities country COVID-19 curative Decoding drug Drug repurposing effective effective vaccine Factor globe Host host-pathogen interaction identification immune response information Intervention less medical intervention Mortality mortality rate mutant virus ontological Ontology pathogen Prevalence researcher respiratory SARS CoV-2 significantly spread to target protein targets the disease therapy unique Vaccine variations virus [DOI] 10.1016/j.imu.2020.100486 [Article Type] Review article
Mental health of Urban Mothers (MUM) study: a multicentre randomised controlled trial, study protocolMUM(도시 어머니의 정신 건강) 연구: 다기관 무작위 대조 시험, 연구 프로토콜Global Health Published on 2020-11-272022-09-10 Journal: BMJ Open [Category] 임상, [키워드] addressed adverse effect analysed analyses Analysis Anxiety Anxiety Disorder anxiety disorders approved center children Chinese clinical conducted consequence COVID-19 COVID-19 pandemic Declaration of Helsinki Depression depression & mood disorders disease disorder dissemination during pregnancy Edinburgh Effect effective Effectiveness ethical review board Ethics expected family friends Generalised anxiety disorder Good Good Clinical Practice Health health problems healthcare Helsinki Hong Kong identify Impact Impact Event in some increased risk Infectious diseases International Internet Intervention IRB Karolinska Institute lead less media mental health Mental health disorder mental health disorders mental health problem mental health problems multicentre National outcome outcomes pandemic peer peer-reviewed perinatology physical Post-traumatic stress disorder Practice Pregnancy pregnant women prenatal randomised randomised controlled trial receive recruited reducing registration number reported reproductive medicine risk score severity Shanghai social distancing social media Sponsor spread to Stress Study protocol Subgroup analyses Support Trial Trial Registration Number university urban usual care women [DOI] 10.1136/bmjopen-2020-041133 PMC 바로가기 [Article Type] Global Health
Ensuring a safe and adequate blood supply during the COVID-19 pandemic: the Moroccan National Blood Center experienceCommentary Published on 2020-11-252022-10-28 Journal: The Pan African Medical Journal [Category] COVID-19, MERS, [키워드] activities Blood blood products blood transfusion centers center China concerning COVID-19 COVID-19 pandemic demonstrated Ensuring Epidemic Health International management measure Morocco national health authority New coronavirus new virus pandemic reactivity Safe spread to the epidemic the SARS-CoV-2 Wuhan [DOI] 10.11604/pamj.2020.37.275.26639 PMC 바로가기 [Article Type] Commentary
SARS-CoV-2 growth, furin-cleavage-site adaptation and neutralization using serum from acutely infected hospitalized COVID-19 patientsSARS-CoV-2 성장, 퓨린 절단 부위 적응 및 급성 감염 입원 COVID-19 환자의 혈청을 사용한 중화Research Article Published on 2020-11-212022-09-10 Journal: The Journal of General Virology [Category] MERS, SARS, 변종, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus adaptation angiotensin antigenic target Betacoronavirus both viruses causative agent caused Cell cell lysate cell surface cells characterized cleavage clinical isolates comparable coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 deaths deleted Deletion demonstrated disease expand furin furin cleavage generate glycoprotein growth hACE2 Healthcare system Healthcare systems hospitalized COVID-19 patient host range human Angiotensin-converting enzyme Human angiotensin-converting enzyme 2 in vitro in vivo indirect immunofluorescence inefficient Infection insertion investigated Like MinION Munich neutralization Neutralizing antibodies neutralizing antibody titre neutralizing antibody titres Pathogenesis patients reached receptor respiratory S glycoprotein S protein SARS-CoV SARS-CoV-2 SARS-CoV-2 spike Sequencing serum serum sample severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 spread to strain the cell the S protein the SARS-CoV-2 variant Vero E6 Vero E6 cell VERO E6 cells virus virus stock virus stocks viruses [DOI] 10.1099/jgv.0.001481 PMC 바로가기 [Article Type] Research Article
Wide-awake local anaesthesia no tourniquet (WALANT) vs regional or general anaesthesia for flexor tendon repair in adults: protocol for a systematic review and meta-analysis성인의 굴곡건 수복을 위한 WALANT(광각성 국소마취 무지혈대) 대 국소 또는 전신 마취: 체계적인 검토 및 메타 분석을 위한 프로토콜Protocol Published on 2020-11-212022-08-31 Journal: Systematic Reviews [Category] Coronavirus, meta-analysis, SARS, [키워드] (epinephrine Abstract Adrenaline Aerosol generation anaesthesia Anaesthetics approach article best CINAHL clinical trial Cochrane Library comparator complications conducted conscious COVID-19 database determine epinephrine evaluate Evidence feasible Finger injuries Flexor tendon Flexor tendon injury flexor tendons functional general anaesthesia Grey Grey literature hand Hand injuries hand surgery healthcare professionals help IMPROVE include Injury intubation investigator knowledge language limitation Local Meta-analysis Methodological quality motion occur open operative time outcome outcome measures Patient peer review Penetrating penetrating injury Potential Primary outcome protocol random effect range of motion reduced reduced risk Referral Registered removal repair required resolved resource risk secondary Secondary outcomes spread to standard treatment Study protocol supplementary material surgeon surgery surgical systematic review Tendon injuries tourniquet undergo WALANT Wide-awake Wide-awake local anaesthesia no tourniquet wrist [DOI] 10.1186/s13643-020-01532-1 PMC 바로가기 [Article Type] Protocol
COVID-19 pandemic crisis—a complete outline of SARS-CoV-2Review Published on 2020-11-172022-10-31 Journal: Future Journal of Pharmaceutical Sciences [Category] COVID-19, [키워드] Abstract Asia Asymptomatic carrier bat Chinese clinical trial clinical trials Complete coronavirus country COVID-19 COVID-19 pandemic Diagnosis effective fatal disease help Host lifecycle overcome pandemic Pathogenesis Patient precautions prevention prophylactic treatment SARS-CoV-2 silent Spread spread to transfer Treatment World Health Organization Wuhan [DOI] 10.1186/s43094-020-00133-y PMC 바로가기 [Article Type] Review
COVID-19 infection in first trimester of pregnancy marked by a liver cytolysis in a woman previously treated by hydroxychloroquine for repeated implantation failure: a case reportCase Report Published on 2020-11-162022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, SARS, [키워드] absence aetiology assessment breathlessness Care Case report caused China clinical feature Comorbidities complications Comprehensive COVID-19 COVID-19 diagnosis COVID-19 infection digestive disease first trimester Foetus French Government gravid growth Hepatic cytolysis Hydroxychloroquine indicated liver monitoring Nasopharyngeal swab nausea Novel coronavirus Occurrence outcomes Patient Perturbation Pregnancy repeated required resolved respiratory symptom risk SARS-CoV-2 SARS-CoV-2 RNA severe symptoms spread to Symptom the patient Toxicity transaminase treated was tested were recorded with COVID-19 women [DOI] 10.1186/s12879-020-05551-0 PMC 바로가기 [Article Type] Case Report
Large-Scale Plasma Analysis Revealed New Mechanisms and Molecules Associated with the Host Response to SARS-CoV-2Article Published on 2020-11-162022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, [키워드] Activation acute respiratory syndrome addition Analysis approach arachidonic acid AUC Biomarkers characterized circulating control groups coronavirus correlated COVID-19 COVID-19 patient death Degradation Effect Evidence fatty acids free fatty acids Host host response Infection key factor Lipid mechanism metabolism metabolomic metabolomics molecule New Pathogenesis pathogenesis of COVID-19 Phosphatidylcholine Phospholipase A2 plasma porphyrins potential biomarkers provide provided response Revealed SARS-CoV-2 SARS-COV-2 infection severity spread to target the disease Therapeutic strategies therapeutic target therapeutic targets Triglyceride tyrosine [DOI] 10.3390/ijms21228623 PMC 바로가기 [Article Type] Article
A Suggested Role of Human Growth Hormone in Control of the COVID-19 PandemicCOVID-19 전염병 통제에서 인간 성장 호르몬의 제안된 역할Endocrinology Published on 2020-11-092022-09-11 Journal: Frontiers in Endocrinology [Category] MERS, SARS, 치료기술, [키워드] affected aggressive course Behavior common factor contagious Control Coronavirus pandemic country Course COVID-19 deficiency distribution Early detection epidemiological Epidemiology females group growth hormone help hormone Human IGF-1 immune system leads life limitation male management morbidity morbidity and mortality observation patient groups patients planet question raised risk Risk factors role secretion Spread spread to the disease unique virus vulnerability worldwide pandemic Wuhan Wuhan, China [DOI] 10.3389/fendo.2020.569633 PMC 바로가기 [Article Type] Endocrinology
Modelling the initial epidemic trends of COVID-19 in Italy, Spain, Germany, and FranceResearch Article Published on 2020-11-092022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] applied basic reproduction number confirmed case country COVID-19 CrI disease Epidemic estimate Europe feature Features France Germany initial Italy lockdown lowest National outbreak reduce Region SEIR social distancing Spain Spread spread to the disease the epidemic Transmissibility transmission rate WHO [DOI] 10.1371/journal.pone.0241743 PMC 바로가기 [Article Type] Research Article