Antibody-Free Rapid Detection of SARS-CoV-2 Proteins Using Corona Phase Molecular Recognition to Accelerate Development Time개발 시간을 가속화하기 위해 코로나 단계 분자 인식을 사용하여 SARS-CoV-2 단백질의 항체 없는 신속한 검출Article Published on 2021-11-092022-09-11 Journal: Analytical Chemistry [Category] MERS, SARS, 진단, 치료기술, 치료법, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibody approach biological activity capture carbon complex conditions Corona coronavirus detection develop development Device ethylene ETHYLENE GLYCOL faster fluorescence detection fluorescent glycol human saliva injection Instrumentation limit of detection molecular N and S proteins nucleocapsid Pandemics phase platform point-of-care Protein Rapid receptor Recognition recognize respiratory response S proteins SARS-CoV-2 SARS-CoV-2 protein SARS-CoV-2 proteins severe acute respiratory syndrome Coronavirus subunit time unique Viral Viral protein Viral proteins [DOI] 10.1021/acs.analchem.1c02889 PMC 바로가기 [Article Type] Article
Definitions and elements of endpoints in phase III randomized trials for the treatment of COVID-19: a cross-sectional analysis of trials registered in ClinicalTrials.govCOVID-19 치료를 위한 3상 무작위 시험에서 평가변수의 정의 및 요소: ClinicalTrials.gov에 등록된 시험의 횡단면 분석Research Published on 2021-11-082022-09-10 Journal: Trials [Category] MERS, SARS, 임상, [키워드] achievement allocation Analysis Characteristics of endpoints Clinical course clinical trial clinical trials collected condition conducted Consensus COVID-19 COVID-19 treatments cross-sectional analysis Definition Diseases downloaded element Endpoint endpoints examined facilitate Frame inclusion criteria Infectious diseases information median non-severe patient non-severe patients phase Phase III trials primary endpoints Primary outcome measures provide randomized trial Registered Result Sample size secondary secondary endpoint secondary outcome measures selected severe and non-severe patients Severe patient severe patients severity time Time frame time frames transcribed Treatment Trial worsening [DOI] 10.1186/s13063-021-05763-y PMC 바로가기 [Article Type] Research
Indwelling Pleural Catheters for Malignant Pleural Effusion A Time for ActionFeature: NCPD Connection Published on 2021-11-052022-10-31 Journal: Home Healthcare Now [Category] Coronavirus, MERS, SARS, [키워드] Action agency Cancer cancers catheter chest pain Complication COVID-19 infection effusion healthcare hematological Hospitalization increasingly Indwelling less lung malignant Medicare occur Patient per day pleura positive balance Quality of life resulting Shortness of breath spread to subsequent Support Symptom management the patient time treatment regimens [DOI] 10.1097/NHH.0000000000001023 PMC 바로가기 [Article Type] Feature: NCPD Connection
Evaluation of the E-Mental Health Mindfulness-Based and Skills-Based “CoPE It” Intervention to Reduce Psychological Distress in Times of COVID-19: Results of a Bicentre Longitudinal StudyPsychiatry Published on 2021-11-042022-10-31 Journal: Frontiers in Psychiatry [Category] COVID-19, [키워드] age analyses Analysis analyzed Anxiety anxiety symptoms applied approach baseline caused clinical cognitive conducted COVID-19 COVID-19 pandemic Depression depressive symptom Depressive symptoms difference distress E-mental health effective Effectiveness Effects evaluated feasibility frequencies Gender Health Health care system Intervention Linear model longitudinal media mental health mental illness mindfulness mindfulness-based stress reduction offer Online intervention outcome overcome pandemic participant post-intervention Primary outcome Psychological distress reducing repeated Result SARS-CoV-2 pandemic Satisfaction secondary Secondary outcomes Self-efficacy significant decrease significant effect significant increase Study protocol Support Symptoms Tertiary therapy thought time Usability [DOI] 10.3389/fpsyt.2021.768132 PMC 바로가기 [Article Type] Psychiatry
24. Longitudinal Assessment of Immune Responses to COVID-19 Vaccines in Solid Organ Transplant RecipientsOral Abstracts Published on 2021-11-042022-10-29 Journal: Open Forum Infectious Diseases [Category] COVID-19, [키워드] 95% CI anti-N IgG anti-RBD anti-S anti-S IgG Anti-S1 antibody assessment baseline black BNT162b2 board cellular response Characteristics Clinical efficacy Cohort collected consultant controls coronavirus disease COVAX COVID COVID-19 COVID-19 vaccine Cutoff DAVID demographics detect domain dose Efficacy enrolled evaluate figure first dose greater healthy healthy control humoral IgG antibodies IgG titer longitudinal magnitude median member mRNA COVID-19 vaccine mRNA vaccine mRNA-1273 natural infection participant Pfizer Phase 3 trials plasma positive positive response prospective cohort study Quanterix Corporation RBD receive recipient recipients reducing Research respond response Result risk SARS-CoV-2 second dose serological response significantly significantly lower Simoa Solid solid organ transplant SOT spike sub-cohort subset T-cell Response table the healthy the SARS-CoV-2 threshold time timepoint timepoints titer Transplant understanding Vaccine vaccine response were excluded were used with COVID-19 [DOI] 10.1093/ofid/ofab466.024 PMC 바로가기 [Article Type] Oral Abstracts
Effects of covid-19 pandemic on life expectancy and premature mortality in 2020: time series analysis in 37 countriesResearch Published on 2021-11-032022-10-28 Journal: The BMJ [Category] COVID-19, Fulltext, MERS, [키워드] 95% confidence interval age and sex Analysis Annual Bulgaria changes in Complete country Denmark Effect Epidemic Evidence excess expected FIVE highest Human Hungary Iceland Lithuania men men and women Mortality mortality data New Norway objective outcome measure pandemic participant Poland Premature reduction in Region Result Russia Seasonal influenza setting South Korea Spain standard life Taiwan the United State time women World Health Organization Year [DOI] 10.1136/bmj-2021-066768 PMC 바로가기 [Article Type] Research
Modeling the differences in the time-series profiles of new COVID-19 daily confirmed cases in 3,108 contiguous U.S. counties: A retrospective analysisResearch Article Published on 2021-11-032022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, [키워드] aggregation analyzed association Cluster Clustering Clusters confirmed case COVID-19 COVID-19 case COVID-19 cases COVID-19 pandemic distribution exhibited Factors geographic location Government identify Local material modeling objective outbreak peaked profile reported Research Result Retrospective analysis time variable was used [DOI] 10.1371/journal.pone.0242896 PMC 바로가기 [Article Type] Research Article
Analysis of SARS-CoV-2 RNA Persistence across Indoor Surface Materials Reveals Best Practices for Environmental Monitoring ProgramsObservation Published on 2021-11-022022-10-29 Journal: mSystems [Category] COVID-19, [키워드] acute respiratory syndrome average can be used Care categories complicate coronavirus coronavirus disease correlated correlation COVID-19 diagnostic effective effort eight environmental monitoring event Evidence experiment group heat-inactivated hospital identify infected individual Infection intensity lab limit of detection Linear regression model material Measures monitoring nine Other outbreak Particle PCR Practice processed Program provide public health quantification quarantine reduced reported Research responses RT-qPCR SARS-CoV-2 SARS-CoV-2 RNA School Schools stability surface surface sampling Surveillance Swab Temporal resolution tested time turn Viral load viral particle Viral particles Viral RNA viral signal virus was performed [DOI] 10.1128/mSystems.01136-21 PMC 바로가기 [Article Type] Observation
Vaccine Development in the Time of COVID-19: The Relevance of the Risklick AI to Assist in Risk Assessment and Optimize PerformanceDigital Health Published on 2021-11-022022-10-31 Journal: Frontiers in Digital Health [Category] COVID-19, [키워드] Analysis appear artificial intelligence assessment coronavirus COVID-19 COVID-19 pandemic COVID-19 vaccine development distribution early phase early stage evaluate incidence increase pandemic performance performed Pharmacology Probability Prognosis Rapid Relevance Research risk risk analysis time Treatment Vaccine Vaccine development vaccine production Vaccines [DOI] 10.3389/fdgth.2021.745674 PMC 바로가기 [Article Type] Digital Health
Time to a Negative SARS-CoV-2 PCR Predicts Delayed Return to Work After Medical Leave in COVID-19 Infected Health Care Workers음성 SARS-CoV-2 PCR에 걸리는 시간, COVID-19에 감염된 의료 종사자의 병가 후 직장 복귀 지연 예측Article Published on 2021-11-012022-09-11 Journal: Journal of occupational and environmental medicine [Category] SARS, 치료기술, [키워드] 95% CI age Analysis association COVID-19 Delayed evaluate Factors HCW HCWs hospital multivariable analyses negative Negative PCR negative RT-PCR Physicians Predictive required return RT-PCR SARS-CoV-2 PCR Sex Support symptom onset time undetectable variable Viral detection work worker [DOI] 10.1097/JOM.0000000000002336 PMC 바로가기 [Article Type] Article