Comparative and kinetic analysis of viral shedding and immunological responses in MERS patients representing a broad spectrum of disease severityArticle Published on 2016-05-052022-10-29 Journal: Scientific Reports [Category] Coronavirus, MERS, [키워드] affecting Analysis analyzed antibody antiviral therapy Blood level chemokine Clinical data Comparative correlated correlation cytokine Deceased disease disease severity early phase effective EGF Factor febrile illness four group hospital IL-10 IL-15 Immunity Immunological response increases in kinetic kinetic analysis knowledge lymphocyte response lymphopenia MERS MERS patient MERS-CoV infection Mild Monocytes Mortality neutrophil outcomes Patient patients Pneumonia prognostic representing required response responses severity specimen Spread TGF-β the patient treated viral loads viral shedding Virological [DOI] 10.1038/srep25359 PMC 바로가기 [Article Type] Article
Abacavir, zidovudine, or stavudine as paediatric tablets for African HIV-infected children (CHAPAS-3): an open-label, parallel-group, randomised controlled trial아바카비르, 지도부딘 또는 스타부딘을 아프리카 HIV 감염 소아용 정제로 사용(CHAPAS-3): 공개 라벨, 병렬 그룹, 무작위 대조 시험Articles Published on 2016-02-012022-09-06 Journal: The Lancet. Infectious Diseases [Category] Communicable Disease, [키워드] abacavir adverse event adverse events African analysed Antiretroviral therapy ART children clinical database Developing drugs dual efavirenz enrolled European finding Follow-up funding groups hazard ratio hypersensitivity hypersensitivity reactions immunological inhibitor Intention intention to treat ISRCTN registry Laboratory lamivudine less Lipodystrophy median median age nevirapine nucleoside occurred Open-label parallel-group partnership primary endpoint randomisation randomised controlled trial Randomised trial Registered responses stavudine suppression Tablet Toxicity Treatment Trial Uganda Viral Viral load Virological were excluded WHO zidovudine [DOI] 10.1016/S1473-3099(15)00319-9 PMC 바로가기 [Article Type] Articles
Experimental feline enteric coronavirus infection reveals an aberrant infection pattern and shedding of mutants with impaired infectivity in enterocyte culturesArticle Published on 2016-01-292022-10-29 Journal: Scientific Reports [Category] Coronavirus, MERS, [키워드] abnormality absence affected antibody blood cell CD8 Clinical sign Clinical signs coronavirus Coronavirus infection Culture Feline infectious peritonitis Hypothesis Immune cell immunological infect Infection Infectious virus intestinal investigated less leukocyte Mild mutant mutated Mutation mutations neutralising antibody not different occurred raise regulatory T cells Replication reveal SPF these cell Viraemia viral genome Virological virus [DOI] 10.1038/srep20022 PMC 바로가기 [Article Type] Article
Public health implications of using various case definitions in The Netherlands during the worldwide SARS outbreakOriginal Articles Published on 2006-08-072022-11-01 Journal: Clinical microbiology and infection : the official [Category] Coronavirus, [키워드] 2003 acute respiratory syndrome analysed assessment Case definition caused Changing Confusion consequence criteria deviation different epidemiological FIVE Health implication Influenza management Measures Netherland outbreak pandemic Patient Perspective Public public health public health threats reported required resources risk Risk assessment SARS Sensitivity and specificity serological the patient the WHO Threats Virological were used [DOI] 10.1111/j.1469-0691.2006.01552.x PMC 바로가기 [Article Type] Original Articles