Repurposing prolactin as a promising immunomodulator for the treatment of COVID-19: Are common Antiemetics the wonder drug to fight coronavirus?COVID-19 치료를 위한 유망한 면역 조절제로 프로락틴 용도 변경: 일반적인 항구토제는 코로나바이러스와 싸우는 놀라운 약물입니까?Article Published on 2020-11-012022-08-31 Journal: Medical Hypotheses [Category] SARS, 신약개발, 치료제, [키워드] adaptive Adaptive immunity antagonist Antiemetics Autoimmune diseases Blood clinical trial conditions conducted coronavirus Course COVID COVID-19 Critical death Domperidone Dopamine drug elevated evade explained hyperprolactinemia hypoprolactinemia Hypothesis immune function immune modulation immune-stimulatory Immunity immunological immunomodulator Immunotherapy in some induce Infection lactogenic lactogenic hormone lead limit long term Metoclopramide Mild nausea nausea and vomiting observation opportunistic infection outcome pathological condition Patient physiological PRL Prolactin Prophylactic reported repurposing SARS-CoV-2 serum Seven survival the patient therapeutic Treatment vomiting women [DOI] 10.1016/j.mehy.2020.110208 PMC 바로가기 [Article Type] Article
Focus on uncommon symptoms of COVID-19: Potential reason for spread of infectionArticle Published on 2020-11-012023-07-12 Journal: Diabetes & metabolic syndrome [Category] SARS, [키워드] Anosmia COVID-19 diarrhea headache vomiting [DOI] 10.1016/j.dsx.2020.09.017 PMC 바로가기
The role of Interleukin-4 in COVID-19 associated male infertility – A hypothesisReview article Published on 2020-11-012022-10-05 Journal: Journal of reproductive immunology [Category] SARS, 유전자 메커니즘, [키워드] abdominal pain ACE-2 ACE-2 receptor activate activated activating Activation ALT Apoptosis AST attenuate Bilirubin Cancer Chronic kidney disease CNS Comorbidity complex COVID-19 COVID-19 patient COVID-19 patients cytokine decrease deregulating Diabetes Mellitus diarrhea dysfunction Hematuria Hypothesis IgE IgG IL-12 IL-4 IL-6 Impaired Infection Inflammation interferons Interleukin-4 Jak-STAT JAK-STAT pathway JAK-STAT signaling Liver injury Lung injury male male infertility morbidity and mortality ocular pandemic pathway populations pro-inflammatory cytokine risk SARS-CoV-2 Signaling STAT Th2 Th2 cell Th2 cells the patient TNF-α triggering vomiting [DOI] 10.1016/j.jri.2020.103213 [Article Type] Review article
Prevalence, Mechanisms, and Implications of Gastrointestinal Symptoms in COVID-19Medicine Published on 2020-10-302022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] abdominal pain acute respiratory syndrome added caused Complication Coronavirus disease 2019 Coronavirus-2 country COVID-19 COVID-19 symptoms deaths diarrhea endoscopy Factor fecal-oral transmission Gastrointestinal gastrointestinal symptoms globe highlight increasingly Infection manifestation mechanism medications nausea outbreak pandemic Prevalence respiratory symptom resulting risk SARS-CoV-2 Spread Stool Symptom symptoms of COVID-19 these symptoms Transmission transmission rate vomiting while Wuhan, China [DOI] 10.3389/fmed.2020.588711 PMC 바로가기 [Article Type] Medicine
Assessments of different inactivating reagents in formulating transmissible gastroenteritis virus vaccineResearch Published on 2020-10-232022-10-28 Journal: Virology Journal [Category] Coronavirus, [키워드] β-propiolactone assessment Binary-ethylenimine cause caused CD4 CD8 cellular cellular immunity characterized control group demonstrated diarrhea Effect effective ELISA evaluated experimental group flow cytometry formaldehyde gastroenteritis group highest histopathological Histopathology Humoral immunity IFN-γ IgG IL-4 immunization inactivated Inactivated vaccine indicated induce Infection lymphocyte macroscopic mice Mortality pathological change pathology performed Peripheral blood positive rate produced proliferation reagent Result spleen subset T lymphocyte TGEV the disease transmissible gastroenteritis virus Transmissible gastroenteritis virus (TGEV) Vaccine virus vomiting [DOI] 10.1186/s12985-020-01433-8 PMC 바로가기 [Article Type] Research
COVID-19 presenting as fulminant hepatic failure A case report4500 Published on 2020-10-232022-10-30 Journal: Medicine [Category] COVID-19, MERS, SARS, [키워드] abdominal pain acute liver failure acute respiratory syndrome Case report cause changes chest pain common consolidation country COVID-19 COVID-19 pandemic deaths described disease dry cough elevations Encephalopathy Evidence fevers fulminant hepatic failure gastrointestinal involvement ground glass opacities had no hepatic failure Hepatitis Hydroxychloroquine Infection instances interstitial limit liver Liver injury lung Lupus Methylprednisolone Mild nausea Patient positive presenting radiologic Respiratory illness respiratory symptoms responsible SARS-CoV-2 SARS-COV-2 infection Shortness of breath shown Significant SLE Spread tested the SARS-CoV-2 transaminase Travel treated unique Viral pneumonia virus vomiting Wuhan, China [DOI] 10.1097/MD.0000000000022818 PMC 바로가기 [Article Type] 4500
Gastrointestinal symptoms and fecal nucleic acid testing of children with 2019 coronavirus disease: a systematic review and meta-analysisArticle Published on 2020-10-202022-10-29 Journal: Scientific Reports [Category] COVID-19, MERS, SARS, [키워드] 95% CI analyzed Attention children children with COVID-19 China clinical manifestation clinical study coronavirus coronavirus disease country COVID-19 COVID-19 patient diarrhea exceeded fecal Gastrointestinal Gastrointestinal symptom gastrointestinal system incidence Meta-analysis much higher nucleic acid Nucleic acid detection paediatrics patients pediatric positive positive rate Prevalence remained respiratory tract specimen specimen Symptom systematic review vomiting was used Wuhan [DOI] 10.1038/s41598-020-74913-0 PMC 바로가기 [Article Type] Article
Coronaviruses and gastrointestinal diseasesReview Published on 2020-10-142022-10-31 Journal: Military Medical Research [Category] COVID-19, MERS, SARS, [키워드] caused coronavirus Coronavirus disease 2019 (COVID-19) cough COVID-19 diarrhea digestive system digestive tract disease Effect Fever gastrointestinal disease gastrointestinal symptoms generate helping human coronaviruses infect less mammal Mammal coronaviruses mammalian new virus pathogenicity receive Respiratory system SARS-CoV-2 shown Symptom vomiting [DOI] 10.1186/s40779-020-00279-z PMC 바로가기 [Article Type] Review
How to boost the immune defence prior to respiratory virus infections with the special focus on coronavirus infectionsReview Published on 2020-10-122022-11-01 Journal: Gut Pathogens [Category] COVID-19, [키워드] “cytokine storm” Abnormalities activation of platelets addition administration anorexia Anxiety boost can be used cause Coagulation Coronavirus infection COVID-19 COVID-19 pandemic Critically ill patient cytokine expression defend diarrhea diarrhoea digestive Factors feature fraction gut microbiota Health healthy helping Human immune immune system immunomodulatory in healthy individual individual intestinal inflammation microbial infection microbial infections modulated novel coronavirus SARS-CoV-2 plasma previous study reduce reduced respiratory tract infection Respiratory virus infection Respiratory virus infections respond risk Saccharomyces cerevisiae shown Stress Support Symptoms synergistic Vaccine viral infections vitamins C vomiting weakened with COVID-19 yeast [DOI] 10.1186/s13099-020-00385-2 PMC 바로가기 [Article Type] Review
Diagnostic value of abdominal sonography in confirmed COVID-19 intensive care patientsResearch Published on 2020-09-292022-10-31 Journal: The Egyptian Journal of Radiology and Nuclear Medicine [Category] COVID-19, [키워드] Abdominal imaging studies abdominal pain age article average bowel Care caused Chest cholestasis Coagulopathy Complication complications of COVID-19 constipation coronavirus disease correlated Course COVID-19 COVID-19 patient diarrhea disease dysfunction evaluated female hematoma Hepatobiliary hepatomegaly HRCT ICU indicated Inpatient intensive care patient intensive care unit laboratory data laboratory result liver function tests male nephropathy Novel coronavirus infection observation occurred outbreak Patient patients performed positive renal function Result Symptom Symptoms the disease the patient these symptom virus vomiting WHO with COVID-19 World Health Organization Wuhan, China [DOI] 10.1186/s43055-020-00317-9 PMC 바로가기 [Article Type] Research