clinical trial – Page 210 – Communicable Diseases Research

Cardiovascular Damage in COVID-19: Therapeutic Approaches Targeting the Renin-Angiotensin-Aldosterone System

Review

Published on 2020-09-042022-10-29
Journal: International Journal of Molecular Sciences [Category] COVID-19,

Iran’s Approach to COVID-19: Evolving Treatment Protocols and Ongoing Clinical Trials

COVID-19에 대한 이란의 접근: 진화하는 치료 프로토콜 및 진행 중인 임상 시험

Review

Published on 2020-09-042022-09-11
Journal: Frontiers in Public Health [Category] MERS, SARS, 치료기술,

[키워드] 2019-nCoV antiviral therapy approach approved Arm avoidance Care clinical clinical trial clinical trials clinically coronavirus disease Coronavirus disease 2019 COVID-19 diagnostic disease disease control Early detection education epidemiological Follow-up followed by Guidance guideline Health care Health care system health care systems Infection prevention and control Iran Laboratory test Laboratory tests management Mild-to-moderate Ministry of Health pandemic pharmacotherapy protocols public health recommendation Registered registry released SARS-CoV-2 symptomatic case symptomatic cases therapeutic Therapeutics Transmission Volume
[DOI] 10.3389/fpubh.2020.551889 PMC 바로가기 [Article Type] Review

Coronavirus Disease 2019 Related Clinical Studies: A Cross-Sectional Analysis

Pharmacology

Published on 2020-09-022022-10-31
Journal: Frontiers in Pharmacology [Category] COVID-19,

SARS-CoV-2 Bound Human Serum Albumin and Systemic Septic Shock

Cardiovascular Medicine

Published on 2020-09-022022-10-31
Journal: Frontiers in Cardiovascular Medicine [Category] COVID-19,

[키워드] acute respiratory distress syndrome age albumin albumin therapy alleviate ARDS binding Bound caused change chronic heart failure circulation clinical trial Coagulopathy Concentration condition coronavirus COVID-19 COVID-19 infection COVID-19 virus diabetes distress distribution doubling Effect endothelial endothelial glycocalyx layer free fatty acid glycocalyx homeostasis Hormones Human Human serum albumin hypertension Hypoalbuminemia independent inhibit initiated key factor liver Logistic maintain mechanism morbidity Mortality occur outcome pandemic pathophysiological Patient plasma plasma protein predict Protein reduce Research SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 virion Sepsis septic Septic shock serum albumin severe respiratory syndrome shown subsequent Symptom syndrome systemic systemic symptom therapy tissues Transport unique urgency vascular disease virion
[DOI] 10.3389/fcvm.2020.00153 PMC 바로가기 [Article Type] Cardiovascular Medicine

Research Collaboration and Outcome Measures of Interventional Clinical Trial Protocols for COVID-19 in China

Public Health

Published on 2020-09-022022-10-31
Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS,

The COVID-19 pandemic: a catalyst to improve clinical trials

Comments & Opinion

Published on 2020-09-012022-10-05
Journal: Nature reviews. Cardiology [Category] 임상,

[키워드] clinical trial COVID-19 IMPROVE
[DOI] 10.1038/s41569-020-00439-7 [Article Type] Comments & Opinion

Developing an Ethics Framework for Allocating Remdesivir in the COVID-19 Pandemic

Review article

Published on 2020-09-012022-10-05
Journal: Mayo Clinic proceedings [Category] SARS, 치료제,

[키워드] addressed allocation antiviral drug approach approved authorization build children clinical trial compassionate-use coronavirus COVID COVID-19 COVID-19 crisis COVID-19 patient Department Department of Health and Human Services Developing drug ECMOextracorporeal membrane oxygenation EHRelectronic health record Electronic health record Emergency Emergency use authorization Ethics EUA EUAemergency use authorization extracorporeal membrane oxygenation FDA FDAFood and Drug Administration food Food and Drug Administration framework Guidance HHSDepartment of Health and Human Services hospital Human Inc. MCECMinnesota COVID Ethics Collaborative MDHMinnesota Department of Health Minnesota COVID Ethics Collaborative Minnesota Department of Health National Institute of Allergy and Infectious Diseases NIAIDNational Institute of Allergy and Infectious Diseases Patient pregnant women public health emergency question raised Remdesivir SATScience Advisory Team Science Advisory Team service SHCCCState Health Care Coordination Center State Health Care Coordination Center state health department treat UMNUniversity of Minnesota University of Minnesota
[DOI] 10.1016/j.mayocp.2020.06.016 [Article Type] Review article

Zinc(II)—The Overlooked Éminence Grise of Chloroquine’s Fight against COVID-19?

Review

Published on 2020-09-012022-10-28
Journal: Pharmaceuticals [Category] COVID-19,

[키워드] 2019-nCoV Chloroquine clinical trial Compound COVID-19 COVID-19 therapeutics HCQ hydroxy- chloroquine Hydroxychloroquine inhibitor Other RNA-dependent RNA polymerase SARS-CoV-2 thought Treatment Zn(II) ionophores
[DOI] 10.3390/ph13090228 PMC 바로가기 [Article Type] Review

Prophylactic (hydroxy)chloroquine in COVID-19: Potential relevance for cardiac arrhythmia risk

Research article

Published on 2020-09-012022-10-05
Journal: Heart Rhythm [Category] SARS, 유전자 메커니즘,

[키워드] acute respiratory syndrome addition addressed affected approach arrhythmia Arrhythmias benefit Cardiac arrhythmia cardiovascular disease Chloroquine clinical trial coronavirus COVID-19 demonstrated disease drugs ECG Effects electrocardiographic Evidence female patient Genetic hospital Hydroxychloroquine induce Infection investigated life-threatening Patient patients with COVID-19 performed Postinfection Potential preventive measure Prophylactic prophylactically Prophylaxis provide QT QT interval QT prolongation recommendation recommendations reduce risk SARS-CoV-2 suggested therapy torsades de pointes Treatment treatment for COVID-19
[DOI] 10.1016/j.hrthm.2020.07.001 [Article Type] Research article

Baricitinib, a drug with potential effect to prevent SARS-COV-2 from entering target cells and control cytokine storm induced by COVID-19

Review article

Published on 2020-09-012022-10-05
Journal: International immunopharmacology [Category] SARS, 치료제,

[키워드] ACE2 ACE2 receptor acute respiratory syndrome Angiotensin-converting enzyme atopic dermatitis Baricitinib C reactive protein Care caused causes Cell cells China clinical benefit Clinical characteristics clinical trial coronavirus COVID-19 CRP cytokine Cytokine storm demonstrated Deterioration develop disease Disease progression drug Efficacy and safety expected inhibit intracellular assembly involved Jak Jak-STAT JAK-STAT pathway Janus kinase Lymphocytes mechanism much lower natural killer Novel coronavirus Patient Pharmaceutical care Pneumonia Prevent pro-inflammatory cytokine proinflammatory reducing reported Research rheumatoid arthritis SARS-CoV-2 SARS-CoV-2 entry severe COVID-19 severe pneumonia Spread surface protein systemic lupus erythematosus target cell the cytokine storm the patient treat Treatment US FDA viral entry
[DOI] 10.1016/j.intimp.2020.106749 [Article Type] Review article