Impact of intravenous lidocaine on clinical outcomes of patients with ARDS during COVID-19 pandemia (LidoCovid): A structured summary of a study protocol for a randomised controlled trial
COVID-19 대유행 중 ARDS 환자의 임상 결과에 대한 정맥내 리도카인의 영향(LidoCovid): 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약
Letter
[키워드] 1:1
24 hour
24 hours
acute renal failure
acute respiratory distress
acute respiratory distress syndrome
Admission
adverse event
adverse events
age
albumin
All participant
All participants
Anti-inflammatory effects
approved
aPTT
ARDS
Atrial fibrillation
Bacterial
Berlin
Beta
Bicarbonate
biological sample
biological samples
blinded
Blinding
blockers
blood count
bolus
bronchospasm
cardiac rhythm
Cardiogenic shock
Care
care providers
Child bearing
clinical
Clinical data
Clinical outcome
clinical study
collected
Commission
comparator
complete blood count
Complication
computer-generated
Concentration
conducted
Consumption
control group
cough
COVID-19
COVID-19 pneumonia
Covid-19 subgroup
CRP
D-dimers
delirium
diagnostic
Disease progression
disorders
dissemination
distribution
Distribution ratio
dosage
Effect
element
ethics committee
evaluate the effect
evaluated
Evolution
experimental group
extubation
ferritin
fibrinogen
FiO2
followed by
following
form
France
French
Gas exchange
HCG
Hospitalized
hypnotics
ICU
IL-6
Ileus
Impact
incidence
include
inclusion criteria
Inflammation
Inflammatory marker
inflammatory markers
intensive care
intensive care unit
interval
intervention group
intravenous
Intubated
investigator
LDH
Length
lidocaine
Local
local anaesthetics
Local anesthetics
Lymphocytes
moderate
moderate to severe
Modification
molecular mechanisms of pharmacological action
Mortality
NaCl
number
objective
Older
opioids
outcome
Pandemia
PaO2
PaO2/FiO2 ratio
parallel group
participant
Patient
patients with ARDS
PCT
Phase 3
Placebo
placebo-controlled
Platelets
Pneumonia
pneumopathy
Pneumothorax
Prevent
Primary outcome
protection
Protective
protocol
QTc
random
randomisation
randomised
randomised controlled trial
randomize
Randomized
Randomly
receive
Recovery time
recruitment
Registered
Renal Dialysis
renal failure
report
respiratory distress
RT-PCR
Sample size
SARS-CoV2 infection
secondary endpoint
Secondary endpoints
sedated
Severe acute respiratory syndrome
severe ARDS
Shock
Social Security
Social security system
sore throat
status
Stratification
stroke
Study protocol
supplementary material
surgical
syndrome
tetraplegia
thromboembolic
Thromboembolic event
timepoint
Toxicity
Treatment
Trial
Trial registration
triglycerides
troponin
two group
two groups
university
vasopressors
Ventilation
ventilator
ventilator-free day
Ventilator-free days
website
women
written Informed Consent
[DOI] 10.1186/s13063-021-05095-x PMC 바로가기 [Article Type] Letter
[DOI] 10.1186/s13063-021-05095-x PMC 바로가기 [Article Type] Letter