Clinical course and challenging management of early COVID-19 infection after heart transplantation: case report of two patients심장 이식 후 초기 COVID-19 감염의 임상 경과 및 어려운 관리: 2명의 환자에 대한 증례 보고Case Reports Published on 2021-01-202022-09-10 Journal: BMC Infectious Diseases [Category] MERS, 치료제, [키워드] addressed Antiviral antiviral monotherapy Asymptomatic carrier Asymptomatic carriers Case report Case series case sery clinical Clinical course Comorbidity coronavirus disease Coronavirus disease 2019 Coronavirus disease 2019 (COVID-19) Course COVID-19 COVID-19 infection described died Donor donors heart Heart transplantation high risk Hydroxychloroquine Immunosuppressed interruption issue management mandatory monotherapy mycophenolate mofetil Patient patients perioperative period poor prognosis positive recipient recipients SARS-CoV-2 virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) severity solid organ solid organ transplant supplementary material tested the disease the SARS-CoV-2 virus two patients [DOI] 10.1186/s12879-021-05793-6 PMC 바로가기 [Article Type] Case Reports
Identification and analysis of long non-coding RNAs and mRNAs in chicken macrophages infected with avian infectious bronchitis coronavirusResearch Article Published on 2021-01-202022-10-28 Journal: BMC Genomics [Category] Coronavirus, MERS, [키워드] addition Affect amino acid metabolism Analysis bronchitis cells cellular chicken competing coronavirus cultured cell differentially expressed down-regulated expression profile Factor Gga-miR-30d HD11 Host IBV IBV infection identification indicated Infectious Bronchitis Virus Innate immunity involved lncRNA Long long non-coding RNA Macrophage miR-146a-5p mRNA mRNAs non-coding RNA nucleic acid metabolism nucleotides Ontology Pathogenesis pathway enrichment provided Result RNA Sequencing subset supplementary material uninfected cells up-regulated viral infections [DOI] 10.1186/s12864-020-07359-3 PMC 바로가기 [Article Type] Research Article
Autopsy findings after long-term treatment of COVID-19 patients with microbiological correlationOriginal Article Published on 2021-01-202022-10-29 Journal: Virchows Archiv [Category] COVID-19, MERS, [키워드] Activation addition Alter Autopsy Clinical management Cohort correlation COVID-19 COVID-19 patient death Diffuse alveolar damage disease early stage Endothelitis extracorporeal membrane oxygenation First wave fungal Fungal infection hospitals intensive care less long-term treatment macrophage activation syndrome MOST Mycosis pandemic coronavirus pathological change Patient patients prevalent Regensburg severely ill patient supplementary material syndrome the disease thrombosis transferred Treatment university was performed [DOI] 10.1007/s00428-020-03014-0 PMC 바로가기 [Article Type] Original Article
Advanced echocardiographic phenotyping of critically ill patients with coronavirus-19 sepsis: a prospective cohort studyResearch Published on 2021-01-202022-10-30 Journal: Journal of Intensive Care [Category] COVID-19, [키워드] Afterload alteration Biomarker cardiac cardiac dysfunction changes characterized clinical impact clinical implications clinical setting Cluster Concentration condition correlated COVID-19 COVID-19 patient COVID-19 sepsis Critically ill Critically ill patient echocardiographic echocardiographic parameter feasibility functions hemodynamic hierarchical clustering homogeneous incidence Interaction males management median age Mortality multivariable analysis myocardial injury parameter Patient physiological positively correlated prospective cohort study recorded Result Sepsis septic patients serum supplementary material therapeutic variable were assessed were measured [DOI] 10.1186/s40560-020-00516-6 PMC 바로가기 [Article Type] Research
Impact of Training and Municipal Support on Primary Health Care–Based Measurement of Alcohol Consumption in Three Latin American Countries: 5-Month Outcome Results of the Quasi-experimental Randomized SCALA TrialOriginal Research Published on 2021-01-192022-10-31 Journal: Journal of General Internal Medicine [Category] COVID-19, [키워드] 95% CI added alcohol AUDIT-C brief advice Care clinical Colombia Combination Consumption Coverage COVID-19 cumulative Effect Health heavy drinking Impact implementation incidence rate Institute for Health Care Improvement intensity Intensive Latin less measurement measurement of alcohol consumption Mexico Mexico City municipal action not differ Patient patients Peru Primary Health Care Primary outcome proportion provided Randomized Registered Registration Result supplementary material Support training was measured [DOI] 10.1007/s11606-020-06503-9 PMC 바로가기 [Article Type] Original Research
Critically ill patients with diabetes and Middle East respiratory syndrome: a multi-center observational studyResearch Article Published on 2021-01-192022-10-28 Journal: BMC Infectious Diseases [Category] Coronavirus, MERS, [키워드] 95% confidence interval acute respiratory distress syndrome clearance Clinical course Clinical data comorbid conditions conducted coronavirus Coronaviruses Corticosteroids Critically ill patient demographic characteristics determine diabete diabetes hospital independent independent risk factor Infection intubation Logistic regression analysis management median time Medical conditions MERS MERS-CoV RNA Middle East Middle East respiratory syndrome Mortality Multivariable regression analysis Odds ratio Older outcome Patient patients with diabete presenting symptom respiratory Respiratory failure Result retrospective cohort study risk factor Saudi Arabia severe disease supplementary material vasopressors was performed [DOI] 10.1186/s12879-021-05771-y PMC 바로가기 [Article Type] Research Article
Higher comorbidities and early death in hospitalized African-American patients with Covid-19Research Article Published on 2021-01-182022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, MERS, [키워드] ACE ACE inhibitor ACE inhibitors Admission African-Americans Analysis angiotensin II receptor blockers ARBs benefit black body mass index Care cause Chronic kidney disease clinical feature Comorbidities Comorbidity consecutive patient Coronary artery disease COVID-19 COVID-19 patient Cox proportional hazard Critical CRP death demonstrated determine Diabetes Mellitus dialysis died Efficacy Escalation favorable effect Glucose groups Health Health disparities Hemodialysis Hospitalization Hospitalized identify in-hospital mortality independent predictor Inpatient Invasive mechanical ventilation Laboratory laboratory data LDH lower mortality majority morbidity and mortality Mortality New York City outcome outcomes pandemic Patient patients performed positive Predictive Prevalence procalcitonin prognostic Racial receive required Result retrospective cohort study significantly suffered supplementary material tested The United States treatment interventions was performed [DOI] 10.1186/s12879-021-05782-9 PMC 바로가기 [Article Type] Research Article
Quality and readability of web-based Arabic health information on COVID-19: an infodemiological studyResearch Article Published on 2021-01-182022-10-28 Journal: BMC Public Health [Category] COVID-19, MERS, [키워드] analyzed Arabic assessment average calculator code COVID-19 criteria eligibility eligible foundation General population GRADE health information infodemiology JAMA journal Level measure misinformation public health Quality reading Result searched simple supplementary material the mean website [DOI] 10.1186/s12889-021-10218-9 PMC 바로가기 [Article Type] Research Article
Predictive value of the neutrophil to lymphocyte ratio for disease deterioration and serious adverse outcomes in patients with COVID-19: a prospective cohort studyResearch Article Published on 2021-01-182022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, MERS, [키워드] 95% confidence interval Admission adverse outcome calculated can be used characteristic city clinical disease Clinical outcome condition COVID-19 Critical cutoff value death defined Deterioration died disease deterioration Disease progression evaluate follow-up period high risk Hospital admission Hospitalization hospitalized patient Isolation lymphocyte Medical resources moderate Negative predictive value neutrophil Neutrophil to lymphocyte ratio NLR novel coronavirus disease objective Patient patients with COVID-19 predict Predictive value Primary outcome prospective cohort study Result secondary outcome sensitivity Septic shock severity Shock subsequent supplementary material Treatment with COVID-19 [DOI] 10.1186/s12879-021-05796-3 PMC 바로가기 [Article Type] Research Article
Evaluation of the efficacy and safety of inhaled magnesium sulphate in combination with standard treatment in patients with moderate or severe COVID-19: A structured summary of a study protocol for a randomised controlled trial중등도 또는 중증 COVID-19 환자에 대한 표준 치료와 함께 흡입 황산마그네슘의 효능 및 안전성 평가: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2021-01-182022-09-10 Journal: Trials [Category] 임상, [키워드] 1:1 acute severe asthma adjuvant therapy Administered Affect airway smooth muscle alveolar Anti-inflammatory anticipated Arm ARMS arterial blood arterial blood oxygen saturation arterial oxygen saturation arteriole Artery Asthma attack basic Blinding block Block randomisation blocks blood oxygen Blood oxygen saturation bradyarrhythmia calcium calcium antagonist cardiovascular disease cardiovascular diseases Chest computed tomography Chest CT chest CT scan clinical clinical impact clinical manifestation clinical manifestations Clinical studies clinical study clinical trials Combination Computed tomography Computer software Confirmed congestive heart failure Control Controlled trial cough COVID-19 criteria defined diagnosis of SARS-CoV-2 dissemination Dyspnoea Effect Effects Efficacy and safety eight element eligible patient Eligible patients excluded FIVE functional heart block hospital Hospital stay Hospitalized hospitalized patient hospitalized patients Hypoxemia hypoxia impairment IMPROVE improvement inclusion criteria induce Infection inhalation Inhaled Intervention intervention arm intravenous intravenously Length Lung injury lung involvement magnesium sulphate Mask moderate myocardial injury nasopharyngeal secretion National nebulized number objective Open-label outcome oxygen oxygen saturation Parallel Arm parenchyma participant Patient patients with moderate PCR performed polymerase chain polymerase chain reaction protocol pulmonary artery pulmonary involvement randomisation randomised randomised controlled trial randomization Randomly randomly divided RCT receive reduce Registered registration number registry respiratory respiratory airway respiratory airways Respiratory function respiratory tract respiratory tract symptoms Sample size SARS-COV-2 infection saturation severe COVID-19 Shortness of breath shown smooth muscle relaxant standard treatment status Study protocol supplementary material Symptom Tehran therapy Trial Trial registration Ventilation Version website with COVID-19 Yazd [DOI] 10.1186/s13063-021-05032-y PMC 바로가기 [Article Type] Letter