Danshensu alleviates pseudo-typed SARS-CoV-2 induced mouse acute lung inflammation
Research
[키워드] ACE2
activated
acute inflammatory response
acute lung inflammation
acute respiratory distress
acute respiratory syndrome
Administered
administration
AGT
alleviate
alteration
antiviral activity
Antiviral effect
Cell
controls
coronavirus
COVID-19 patient
damaged
EC50
entry of SARS-CoV-2
expressed
expression
HEK-293T cell
in vitro
in vivo
induce
infected with SARS-CoV-2
Infection
inflammatory cell infiltration
Inflammatory cytokines
inhibit
inhibited
intravenous
investigated
low expression
lung inflammatory response
lung tissue
mechanism
mice
Mortality
mRNA level
NF-κB
Potential treatment
progression
respiratory inflammation
Salvia miltiorrhiza
SARS-CoV-2
SARS-COV-2 infection
SARS-CoV-2 S
syndrome
target cells
Therapeutics
TLR4
treated
Treatment
VERO-E6
virus
virus assay
VSV-G
[DOI] 10.1038/s41401-021-00714-4 [Article Type] Research
[DOI] 10.1038/s41401-021-00714-4 [Article Type] Research