Comparison of the Performance of the PanBio COVID-19 Antigen Test in SARS-CoV-2 B.1.1.7 (Alpha) Variants versus non-B.1.1.7 VariantsSARS-CoV-2 B.1.1.7(알파) 변이체와 비 B.1.1.7 변이체에서 PanBio COVID-19 항원 테스트의 성능 비교Research Article Published on 2021-11-242022-09-10 Journal: Microbiology Spectrum [Category] MERS, SARS, 변종, 진단, 치료기술, [키워드] (alpha Alpha Alpha variant Antigen antigen test antigen tests B.1.1.7 B.1.1.7 variant classical COVID-19 COVID-19 cases detect diagnostic diagnostics epidemiologically evaluate evaluated Evidence example FDA hospital Hospital infection control Hospital staff Hypothesis infecting Infection infection control market Netherlands other variant performance presenting provide Region SARS-CoV-2 SARS-CoV-2 B.1.1.7 Schools sensitivity significantly significantly lower Symptoms Test tested the SARS-CoV-2 Travel variant variant of SARS-CoV-2 variants variants of SARS-CoV-2 Viral Viral load viral variant virus VoC [DOI] 10.1128/Spectrum.00884-21 PMC 바로가기 [Article Type] Research Article
Mechanistic principles of an ultra-long bovine CDR reveal strategies for antibody designArticle Published on 2021-11-182022-10-29 Journal: Nature Communications [Category] COVID-19, MERS, SARS, [키워드] Alpha variant antibodies antibody Antibody structure Antigen Biochemistry bovine CDR CDRs complementarity-determining region contribute Critical de novo disulfide bond Efficiency experiment feature flexible high affinity Interaction MD simulation neutralize Neutralizing organized Protein Protein design remained residue SARS-CoV-2 Spike protein stability the SARS-CoV-2 unique [DOI] 10.1038/s41467-021-27103-z PMC 바로가기 [Article Type] Article
Household Transmission of SARS-CoV-2: A Prospective Longitudinal Study Showing Higher Viral Load and Increased Transmissibility of the Alpha Variant Compared to Previous StrainsArticle Published on 2021-11-172022-10-29 Journal: Microorganisms [Category] COVID-19, [키워드] Adults Alpha variant Asymptomatic B.1.1.7 biological sample concern confirmed COVID-19 case Contact contagious COVID-19 ddPCR digital PCR Effectiveness eight household household contact household contacts household transmission Increased load longitudinal occurred participant Prospective Questionnaires real-time RT-PCR recruited reduce reduced Risk factors risk of transmission SAR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 transmission secondary attack rate significantly higher strain Transmission Vaccine variant variants Viral load virus viruses were used Whole genome sequencing [DOI] 10.3390/microorganisms9112371 PMC 바로가기 [Article Type] Article
Alpha variant SARS-CoV-2 infection: How it all starts알파 변종 SARS-CoV-2 감염: 모든 시작 방법Commentary Published on 2021-11-172022-09-11 Journal: EBioMedicine [Category] MERS, SARS, 변종, 진단, [키워드] Alpha variant SARS-CoV-2 [DOI] 10.1016/j.ebiom.2021.103703 PMC 바로가기 [Article Type] Commentary
COVID-19 Delta Variant: Perceptions, Worries, and Vaccine-Booster Acceptability among Healthcare WorkersArticle Published on 2021-11-172022-10-31 Journal: International journal for equity in health [Category] COVID-19, [키워드] acceptability alleviate Alpha variant BNT162b2 vaccine booster booster dose COVID-19 COVID-19 Delta variant COVID-19 vaccine booster Delta delta variant disseminate dose effective effort evaluate exhibited Factor fraction globe HCW HCWs healthcare healthcare workers’ perceptions information knowledge media mRNA vaccine Nurses participant participated Pfizer-BioNTech physician public health questionnaire receive receiving recommendation Research Saudi Arabia Spread Still travel worry vaccination Vaccine variant worker [DOI] 10.3390/healthcare9111566 PMC 바로가기 [Article Type] Article
Relative Consolidation of the Kappa Variant Pre-Dates the Massive Second Wave of COVID-19 in IndiaKappa 변이의 상대적 통합은 인도에서 COVID-19의 대규모 2차 물결보다 앞서 있습니다.Article Published on 2021-11-162022-09-10 Journal: Genes [Category] MERS, SARS, 변종, 유전자 메커니즘, [키워드] Alpha variant B.1.617.1 B.1.617.2 consolidation COVID-19 delta variant diagnosed driven by Evolution First wave IMPROVE India ion torrent kappa variant and delta variant L452R lab Local massive mechanism Mutation National next generation sequencing P681R Phylogenetic analysis positive sample precursor Randomly relative SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genome sequence SARS-CoV-2 virus second second wave selected sequenced genome Sequencing Spike protein suggested the SARS-CoV-2 virus the spike protein variant Viral viral variant Viral variants Wave whole genome Whole genome sequencing [DOI] 10.3390/genes12111803 PMC 바로가기 [Article Type] Article
Effectiveness and safety of SARS-CoV-2 vaccine in real-world studies: a systematic review and meta-analysis실제 연구에서 SARS-CoV-2 백신의 효과 및 안전성: 체계적인 검토 및 메타 분석Review Published on 2021-11-142022-09-10 Journal: Infectious Diseases of Poverty [Category] MERS, SARS, 변종, [키워드] 95% CI 95% confidence interval Admissions adverse event adverse events Alpha Alpha variant Beta Beta variant coronavirus disease Coronavirus disease 2019 Coverage COVID-19 COVID-19 vaccine COVID-19 vaccines COVID-19-related death death delta variant dose effective Effectiveness evaluate examined Final Gamma global pandemic herd immunity Hospitalization ICU ICU admissions immune immune surveillance Immunity inception incidence rate increasingly Infection intensive care unit Meta-analysis Mutation observational studies observational study pandemic Prevent protective effect random-effects Rapid reduce Result resulting Safety SARS-CoV-2 SARS-CoV-2 infections SARS-CoV-2 vaccine SARS-CoV-2 vaccines SARS-CoV-2 variants searched severe adverse events severe cases single dose supplementary material Surveillance symptomatic symptomatic cases symptomatic COVID-19 systematic review vaccination Vaccine variant variants Web of Science were used [DOI] 10.1186/s40249-021-00915-3 PMC 바로가기 [Article Type] Review
Exposing structural variations in SARS-CoV-2 evolutionSARS-CoV-2 진화의 구조적 변이 노출Article Published on 2021-11-112022-09-10 Journal: Scientific Reports [Category] MERS, SARS, 변종, [키워드] ACE2 acute disease Affect affinity aligned Alpha Alpha variant Analysis B.1.1.7 B.1.617.2 conformational change conformations contributed coronavirus Course Critical delta variant disease effective Effectiveness Evolution function human cells integration lack Lineage Lineage B.1.1.7 Mutation mutations Physicochemical properties physicochemical property physiochemical property Protein protein sequence protein structure residue SARS-CoV SARS-CoV-2 SARS-CoV-2 evolution SARS-CoV-2 variants Spike protein Structural analysis structural biology Structural variation structural variations Structure structures the SARS-CoV-2 Vaccine variant Viral viral infection virus Virus evolution [DOI] 10.1038/s41598-021-01650-3 PMC 바로가기 [Article Type] Article
SARS-CoV-2 Infection in One Cat and Three Dogs Living in COVID-19-Positive Households in Madrid, SpainVeterinary Science Published on 2021-11-102022-11-01 Journal: Frontiers in Veterinary Science [Category] COVID-19, [키워드] Alpha Alpha variant Analysis Asymptomatic B.1.1.7 lineage biochemical Blood bronchoalveolar cat Clinical signs collected Complete coughing COVID-19 COVID-19-positive households cycle threshold determine discharge dog Dyspnea exhibited Fever Genome healthy household IgG response Lineage B.1.1.7 lowest Mild nasal nasopharyngeal Oropharyngeal physical exam positive profiles Real-time reverse-transcription PCR rectal swab remained RT-qPCR SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 genome sequencing SARS-COV-2 infection SARS-CoV-2 testing seroconverted serology seronegative Spain variant virus weakness [DOI] 10.3389/fvets.2021.779341 PMC 바로가기 [Article Type] Veterinary Science
Transmission dynamics and susceptibility patterns of SARS‐CoV‐2 in domestic, farmed and wild animals: Sustainable One Health surveillance for conservation and public health to prevent future epidemics and pandemicsReview Published on 2021-11-092023-06-15 Journal: Transboundary and emerging diseases [Category] MERS, SARS, [키워드] Rhinolophus bats Alpha variant COVID‐19 delta variant horseshoe bat mink pangolin [DOI] 10.1111/tbed.14356 PMC 바로가기 [Article Type] Review