Cytomegalovirus Management in Solid Organ Transplant Recipients: A Pre-COVID-19 Survey From the Working Group of the European Society for Organ Transplantation고형 장기 이식 환자의 거대 세포 바이러스 관리: 장기 이식을 위한 유럽 학회 실무 그룹의 코로나19 이전 설문조사Article Published on 2022-06-222022-09-11 Journal: Transplant International [Category] Coronavirus, 치료제, [키워드] activity Administered aligned approach cause cellular cellular immunity Clinical practice CMV conducted cytomegalovirus Diagnosis disease DNA Efficacy ESOT European evaluate finding Ganciclovir group help heterogenous hospital Infection infection cytomegalovirus International management organ organ transplantation Pathogens Patient pre-emptive therapy Prevent professional Prophylaxis ranged recipient recipients representing response Society Solid solid organ solid organ transplantation SOT strain survey threshold Transplant transplantation Treatment unmet need Valganciclovir working [DOI] 10.3389/ti.2022.10332 PMC 바로가기 [Article Type] Article
Intramyocardial Inflammation after COVID-19 Vaccination: An Endomyocardial Biopsy-Proven Case SeriesCOVID-19 백신 접종 후 심근내 염증: 심근내막 생검으로 입증된 사례 시리즈Article Published on 2022-06-222022-09-11 Journal: International Journal of Molecular Sciences [Category] COVID19(2023년), SARS, 치료기술, [키워드] administration Analysis can not Cardiomyopathy Case report causal relationship cause CD4 CD8 Cell clinical suspicion Comirnaty connection COVID-19 COVID-19 vaccination criteria demonstrated Diagnosis Differential analysis dominance Ejection fraction EMB Endomyocardial biopsy epidemiological excluded expression of SARS-CoV-2 Giant giant cell giant cell myocarditis heart histopathological increased risk individual infectious Inflammatory inflammatory cardiomyopathy Inflammatory marker inflammatory markers Inflammatory response investigated janssen Johnson & Johnson LVEF male mRNA mRNA-based vaccines Myocardial inflammation myocarditis nine Occurrence Patient patients Pfizer-BioNTech reduced reported SARS-CoV-2 SARS-CoV-2 spike protein Sery Spike protein T cell T cells the vaccine triggered vaccination Vaxzevria [DOI] 10.3390/ijms23136940 PMC 바로가기 [Article Type] Article
Target capture sequencing reveals a monoclonal outbreak of respiratory syncytial virus B infections among adult hematologic patients표적 포획 시퀀싱은 성인 혈액학 환자들 사이에서 호흡기 세포융합 바이러스 B 감염의 단일 클론 발병을 보여줍니다Article Published on 2022-06-212022-09-11 Journal: Antimicrobial Resistance and Infection Control [Category] Coronavirus, 변종, 치료기술, 치료제, [키워드] Analysis approach capture Capture probe sequencing capture sequencing cause caused circulating clinical samples contribute contributed Course COVID-19 pandemic demonstrated described disease Early detection effective Genome hematologic Hematologic malignancy hematological hematology hospital Hospital staff increased risk Infection infection control integration involved Isolation measure Measures molecular molecular analysis Molecular epidemiology monoclonal occur oligonucleotide probe outbreak Patient probe respiratory respiratory syncytial virus respiratory tract infection Respiratory tract infections respiratory virus respiratory viruses reveal RSV sequence Sequencing significantly strain target targeted prevention transmission pathways variant virus ward was performed whole-genome sequencing Winter [DOI] 10.1186/s13756-022-01120-z PMC 바로가기 [Article Type] Article
Dnah9 mutant mice and organoid models recapitulate the clinical features of patients with PCD and provide an excellent platform for drug screening Research Published on 2022-06-212022-10-05 Journal: Cell Death & Disease [Category] 변종, [키워드] affected airway Analysis Arm Bioinformatic can be used cause caused ciliary clinical feature co-immunoprecipitation demonstrated DNAH9 drug Drug screening etiology expression feature functional genetic disease identify Immune cell infiltration infections lack lung failure Lung function mice mimicking mutant Mutation outcome Pathogenesis Patient patients performed Phenotypes platform Protein protein levels randomization Respiratory tract infections responsible shown the patient Therapies western blot Western blot analysis [DOI] 10.1038/s41419-022-05010-5 [Article Type] Research
SARS-CoV-2 Omicron variant causes mild pathology in the upper and lower respiratory tract of hamstersSARS-CoV-2 오미크론 변이체는 햄스터의 상부 및 하부 호흡기에서 가벼운 병리를 유발합니다Article Published on 2022-06-202022-09-11 Journal: Nature Communications [Category] COVID19(2023년), SARS, 변종, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 alveolar cause caused changes in Coronavirus-2 Delta Gamma hamster hamsters Infection infectious virus titer infectious virus titers intranasal investigated lesion Lower respiratory tract lung Mild Olfactory epithelium omicron pathogenicity pathological pathology respiratory tissue respiratory tissues rhinitis RNA SARS-CoV-2 Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus Strains Syrian golden hamster Syrian Golden hamsters upper and lower respiratory tract upper and lower respiratory tracts variant variants variants of concern Viral antigen virus spread VoC VOCs [DOI] 10.1038/s41467-022-31200-y PMC 바로가기 [Article Type] Article
Thoracic imaging tests for the diagnosis of COVID‐19Article Published on 2022-06-162022-10-06 Journal: Cochrane database of systematic reviews [Category] COVID19(2023년), SARS, 진단, [키워드] 95% CI 95% confidence interval Accuracy age applicability articles Asymptomatic Asymptomatic individuals cause CDC Chest Chest CT Clinical sign Combination comparison Computed tomography concern COVID‐19 criteria CT findings Definition diagnosing Diagnosis diagnostic Effect eight estimate estimates evaluate evaluated Evidence example excluded Final heterogeneity imaging imaging test indicated individual initial library limit lung MOST participant Participants Pneumonia polymerase chain positive ranged recruited reference reference standard Repository Respiratory illness resulting risk of bia RT‐PCR SARS‐CoV‐2 infection screened searched sensitivity Sensitivity and specificity Seven specificity Stephen Symptoms Thoracic threshold transcriptase University of Bern utility [DOI] 10.1002/14651858.CD013639.pub5 [Article Type] Article
Impact of COVID-19 on the mental health of public university hospital workers in Brazil: A cohort-based analysis of 32,691 workersObservational Study Published on 2022-06-162022-10-04 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 임상, [키워드] absence Analysis analyzed Brazil Care cause causes COVID-19 COVID-19 pandemic evaluate Health health system highlighting Impact increase in Mental mental health mental illness observation period Odds ratio pandemic physical professional professionals reduction reduction in repeated measure Result risk SARS-COV-2 infection Support university hospital was performed work [DOI] 10.1371/journal.pone.0269318 PMC 바로가기 [Article Type] Observational Study
Neurological sequela and disruption of neuron-glia homeostasis in SARS-CoV-2 infectionSARS-CoV-2 감염에서 신경교세포 항상성의 신경학적 후유증 및 붕괴Review Published on 2022-06-152022-09-12 Journal: Neurobiology of disease [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] acute respiratory syndrome Astrocyte autonomous Axon beta-coronavirus cause caused clinical presentation condition coronavirus coronavirus disease COVID-19 COVID-19 infection COVID-19 patients Cytokine storm death Diagnosis effective therapy Extracellular vesicles facilitate homeostasis immune system IMPROVE indicate Infection Injury intubation knowledge long-lasting microglia mitigate molecular Multi-organ damage Neuroinflammation neurologic neurological Neuron occur Oligodendrocyte Oligodendrocyte. outcomes pandemic pathology Pathomechanism Patient potential therapeutic target Prevent Respiratory failure responsible RNA SARS-CoV-2 SARS-COV-2 infection Severe COVID-19 Infection single-stranded systemic inflammatory response tissue Treatment [DOI] 10.1016/j.nbd.2022.105715 PMC 바로가기 [Article Type] Review
Urine metabolomics links dysregulation of the tryptophan-kynurenine pathway to inflammation and severity of COVID-19소변 대사체학은 트립토판-키누레닌 경로의 조절 장애를 COVID-19의 염증 및 중증도와 연결합니다Article Published on 2022-06-152022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), MERS, SARS, 바이오마커, 유전자 메커니즘, 치료기술, 치료법, [키워드] 3-hydroxykynurenine alteration Amino acid amino acids association Biomarker Biomarkers cause changes in Control coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 severity Critical disease severity dysfunction dysregulation healthy controls; Host immune response Increased Inflammation investigated Kynurenine kynurenines metabolism metabolite metabolomic profiling metabolomics Neutral pathway patients hospitalized performed proline proximal proximal tubule Quantitative SARS-CoV-2 SARS-CoV-2 infected patients SARS-COV-2 infection serum severity severity of COVID-19 Support systemic inflammation Transport Tryptophan Urine with COVID-19 [DOI] 10.1038/s41598-022-14292-w PMC 바로가기 [Article Type] Article
Effect of internet-delivered cognitive behavioral therapy on insomnia in convalescent patients with COVID-19: Protocol for a systematic review and meta-analysis인터넷 제공 인지 행동 치료가 코로나19 회복기 환자의 불면증에 미치는 영향: 체계적인 검토 및 메타 분석을 위한 프로토콜Article Published on 2022-06-142022-09-11 Journal: PLoS ONE [Category] MERS, meta-analysis, [키워드] 95% CI addition addressed behavioral therapy cause CBM Chinese Chinese Biomedical Literature Database clinical CNKI Cochrane Library cognitive cognitive behavioral therapy conducted continuous variable continuous variables convalescence convalescent patient Convalescent patients coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients Data analysis Effect epidemicity evaluate the effect evaluated Evidence Grey literature Guidance heterogeneity IMPROVE inception indicated information Infrastructure Insomnia Intervention life literature mean difference Meta-analysis meta-analysis and systematic review positive Previous studies Prospective PROSPERO public health threat Quality of life recent reduce Registered registration number researcher review searched standardized mean difference Stata software systematic review systematic reviews therapy Treatment Trial used to calculate Version Web of Science with COVID-19 [DOI] 10.1371/journal.pone.0269882 PMC 바로가기 [Article Type] Article