In Silico Identification and Validation of Organic Triazole Based Ligands as Potential Inhibitory Drug Compounds of SARS-CoV-2 Main ProteaseArticle Published on 2021-10-142022-10-30 Journal: Molecules [Category] COVID-19, MERS, SARS, [키워드] activity analyzed anti-SARS-CoV-2 therapeutics bemcentinib binding affinity Bisoctrizole candidate caused collected Compound contagious coronavirus docking drug DrugBank database Human identification in silico analysis inhibiting Interaction M pro macromolecular main protease MD simulation molecular MPro organic pandemic parameter pharmacokinetic polyprotein Potential proportions protease Research SARS-CoV-2 SARS-CoV-2 main protease SARS-CoV-2 virus stability Structure targeted therapy the SARS-CoV-2 the SARS-CoV-2 virus these compound translated triazole validation variants Viral RNA virus were assessed [DOI] 10.3390/molecules26206199 PMC 바로가기 [Article Type] Article
A Spatial Analysis of COVID-19 in African Countries: Evaluating the Effects of Socio-Economic Vulnerabilities and NeighbouringArticle Published on 2021-10-142022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, SARS, [키워드] African analyzed available data average Characteristics contagious Coronavirus (COVID-19) pandemic coronavirus disease country country-level disparities COVID COVID-19 COVID-19 cases COVID-19 pandemic COVID-19 testing dependent on Effect Evaluating First wave global public health influence less median Modification Older outbreak P -value pandemic Prevalence proportion regression models Repository respond second wave spatial regression analysis sub-Saharan Africa viral infection vulnerability Wuhan, China [DOI] 10.3390/ijerph182010783 PMC 바로가기 [Article Type] Article
A model for the spread of infectious diseases compatible with case dataResearch Articles Published on 2021-10-132022-10-29 Journal: Proceedings. Mathematical, Physical, and Engineering Sciences [Category] COVID-19, [키워드] Asymptomatic basic reproduction number China compartmental model contagious contrary COVID-19 disease Effect Epidemic Epidemics epidemiological Epidemiology feasible herd immunity Immunity Infection infection rate Infectious disease instantaneous Intervention Italy Laboratory tests less measure observation overcome populations reported SIR and SEIR models South Korea Spread suppressed the epidemic tuning vaccination Vaccines [DOI] 10.1098/rspa.2021.0551 PMC 바로가기 [Article Type] Research Articles
Inhibition Potencies of Phytochemicals Derived from Sesame Against SARS-CoV-2 Main Protease: A Molecular Docking and Simulation StudyChemistry Published on 2021-10-082022-10-31 Journal: Frontiers in Chemistry [Category] COVID-19, [키워드] 3CL pro ADME Against binding caused Compound condition contagious COVID-19 COVID-19 pandemic disease distribution drug target enzyme evaluated FIVE Free energy calculation high mortality rate inhibition M pro main protease metabolism metabolite metabolites molecular molecular docking Molecular dynamics simulation molecular dynamics simulations molecular interaction natural compounds overcome phytochemical potency protease SARS-CoV-2 screened sesame sesamin Simulation Spread stability Therapeutics these compound treating COVID-19 Treatment viral replication Virtual screening was performed [DOI] 10.3389/fchem.2021.744376 PMC 바로가기 [Article Type] Chemistry
Value of the Neutrophil-Lymphocyte Ratio in Predicting COVID-19 Severity: A Meta-analysisCOVID-19 심각도 예측에서 호중구-림프구 비율의 가치: 메타 분석Meta-Analysis Published on 2021-10-082022-09-10 Journal: Disease Markers [Category] MERS, SARS, 바이오마커, [키워드] 95% CI 95% confidence interval Analysis analyzed AUC can be used Cochrane Library conducted contagious coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 case COVID-19 cases determine diagnostic identify Indicator Laboratory likelihood ratio Meta-analysis negative correlation NLR Odds ratio Patient patients positive Ratio Result sensitivity Sensitivity and specificity severe disease severity of COVID-19 specificity Spread Stata value [DOI] 10.1155/2021/2571912 PMC 바로가기 [Article Type] Meta-Analysis
Parallel Pandemics Illustrate the Need for One Health SolutionsMicrobiology Published on 2021-10-082022-10-31 Journal: Frontiers in Microbiology [Category] COVID-19, [키워드] African African swine fever approach benefit changes in China combating contagious COVID-19 COVID-19 pandemic creating disease surveillance and control driven by effective environmental health Epidemic events food insecurity global public health Health Impact Intervention lack one health overcome pandemic Pandemics proportion Protein public health reached reported required solution Spread Surveillance threat Vaccine viral infection [DOI] 10.3389/fmicb.2021.718546 PMC 바로가기 [Article Type] Microbiology
Evaluating the Dynamics of Bluetooth Low Energy Based COVID-19 Risk Estimation for Educational InstitutesArticle Published on 2021-10-072022-10-29 Journal: Sensors (Basel, Switzerland) [Category] COVID-19, MERS, SARS, [키워드] Accuracy activity actual risk BLE Bluetooth can be used characteristic classification Classifier complement Confusion Contact contagious country COVID-19 determine Dynamics energy Epidemic epidemic model estimates estimation Evaluating f-score feature Government high risk investigated limitation machine learning physical Research risk ROC Spread susceptible threshold transmissions virus viruses [DOI] 10.3390/s21196667 PMC 바로가기 [Article Type] Article
Assessment of knowledge, attitude and practice toward COVID-19 and associated factors among health care workers in Silte Zone, Southern EthiopiaResearch Article Published on 2021-10-052022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] 95% CI AOR assessment association Binary logistic regression caused conducted Contact contagious coronavirus COVID-19 COVID-19 infection cross-sectional disease Factor General population Health Health care worker health care workers healthcare worker hospital independent variables infected individuals information Intervention knowledge majority MSC Novel coronavirus objective Older age outcome pandemic positive attitude Prevalence professional proportion questionnaire Respiratory disease Result resulting SARS-CoV 2 selected significantly stratified Study design susceptible Type was used work working [DOI] 10.1371/journal.pone.0257058 PMC 바로가기 [Article Type] Research Article
Post-COVID Public Health Surveillance and Privacy Expectations in the United States: Scenario-Based Interview StudyOriginal Paper Published on 2021-10-052022-10-31 Journal: JMIR mHealth and uHealth [Category] Coronavirus, MERS, SARS, [키워드] Analysis analyzed Care collected conducted consequence contagious COVID-19 COVID-19 pandemic Efficacy elicit expectation expected form greater Health Health care system Health surveillance highlight Impact implication include indicated individual Infrastructure interview mitigate objective outbreak pandemic pandemic-tracking apps participant Patient Potential privacy Privacy concerns Public public health raise raised Result scenario semistructured interview Surveillance the disease the United State The United States thematic analysis transcript while [DOI] 10.2196/30871 PMC 바로가기 [Article Type] Original Paper
Biological Risk in Italian Prisons: From the COVID-19 Management to the Development of a Standardized Model for Emergency ResponseArticle Published on 2021-10-012022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, SARS, [키워드] addition administration adopted approved Biological biological risk communicable diseases contagious contingency plan COVID-19 COVID-19 outbreak COVID-19 pandemic Critical Deceased development disease draft Emergency Epidemics epidemiological feature General population handling Health highlight indoor facilities information International Italian Local measure Model National National Health Service Outbreaks prison prison system public health recommendation resource respond response service sick summer WHO’ [DOI] 10.3390/ijerph181910353 PMC 바로가기 [Article Type] Article