Chromosomal Copy Number Variation, Selection and Uneven Rates of Recombination Reveal Cryptic Genome Diversity Linked to Pathogenicity염색체 복사 수 변이, 선택 및 재조합의 불균등한 비율은 병원성과 관련된 비밀 게놈 다양성을 나타냅니다Research Article Published on 2013-08-152022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] adaptive addition analysis asexual association Author Batrachochytrium dendrobatidis change changes in characterized chromosomal chromosome contribute contributed copy copy number Culture de novo directional Diversity ecological niche ecological niches effort Evidence evidence of Evolution explain Factors feature fungal fungi Gene Genetic Genome genomes growth Host hot spots in vitro infect isolate knowledge Lineage lineages majority manifested mechanism microbial number occur organism pathogen pathogenicity Pathogens phenotypic ploidy Rate Recombination Region replicate reported reproduction response Secretome Selection sequenced target Transmission Variability Variation virulence virulence factors widespread [DOI] 10.1371/journal.pgen.1003703 PMC 바로가기 [Article Type] Research Article
Arabidopsis thaliana RESISTANCE TO FUSARIUM OXYSPORUM 2 Implicates Tyrosine-Sulfated Peptide Signaling in Susceptibility and Resistance to Root InfectionArabidopsis thaliana FUSARIUM OXYSPORUM 2에 대한 내성은 뿌리 감염에 대한 감수성과 내성에 티로신-황산염 신호 전달을 의미합니다Research Article Published on 2013-05-232022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] acting Affect Arabidopsis thaliana Diversity downregulate effector explain expression Extracellular Fusarium Gene Genes host immunity induce Infection inhibit lethal leucine loci locus mutant mutants negative feedback pathogen-specific peptide plant promote Protein provide QTLs Quantitative receptor Regulation related relative susceptibility replaced resistance root Signaling Support suppresse susceptibility traits transgenic tyrosine Vascular while [DOI] 10.1371/journal.pgen.1003525 PMC 바로가기 [Article Type] Research Article
Intrahost Diversity of Feline Coronavirus: A Consensus between the Circulating Virulent/Avirulent Strains and the Internal Mutation Hypotheses?Research Article Published on 2013-03-272022-10-29 Journal: The Scientific World Journal [Category] Coronavirus, [키워드] Amino acid amino acid changes change circulating concerning coronavirus different Diversity evaluate found hypothese Hypothesis in vivo infectious internal Lineage M gene membrane molecular Mutation NO Pathogenesis positive Randomly sequence identity Sequencing SNP strain virulent virus [DOI] 10.1155/2013/572325 PMC 바로가기 [Article Type] Research Article
Genetic Diversity of Spike, 3a, 3b and E Genes of Infectious Bronchitis Viruses and Emergence of New Recombinants in KoreaArticle Published on 2013-01-312022-10-28 Journal: Viruses [Category] Coronavirus, [키워드] analysis Analysis Cluster Clustering coding region conducted determined Diversity E gene emergence FIVE Gene genetic diversity Genotype genotypes IBV Infectious Bronchitis Virus Infectious bronchitis virus (IBV) information insertion isolate mass Molecular epidemiology New not found nucleotide nucleotide sequence Phylogenetic Phylogenetic analysis Phylogenetic tree prevalent recombinant recombinants Recombination S gene sequence similarity spike Vaccine virus viruses [DOI] 10.3390/v5020550 PMC 바로가기 [Article Type] Article
The Role of Viral Population Diversity in Adaptation of Bovine Coronavirus to New Host EnvironmentsResearch Article Published on 2013-01-072022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] adaptation amplified arginine residues average coverage binding bovine Bovine coronavirus cell type coded consensus sequence coronavirus coronavirus Coronaviruses de novo mutation deep deep sequencing different Diversity Environment events fixation Frequency Genetic genetic diversity Genome genomic change Genotype high mutation rate Host host cells Hypothesis indicated infect Infected Infection lung cell line lung cell lines Macrophage macrophages Multiple Mutation Nasal sample New nucleotide occurred Pathogens Point mutation Population quasispecy respond RNA virus role selective pressure sequenced Sequencing spike gene strain subsequent Support virus was used were used [DOI] 10.1371/journal.pone.0052752 PMC 바로가기 [Article Type] Research Article
Yeast Based Small Molecule Screen for Inhibitors of SARS-CoVResearch Article Published on 2011-12-022022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] activities activity Alter bypasse Cell culture cells cellular connection conserved Course demonstrated deubiquitinase Diversity expressed functional growth human coronaviruses induce induction Influenza virus inhibit inhibited inhibiting the function inhibitor inhibitory compounds investigated likelihood mammalian cells mechanism modify molecule Mortality NIH outbreak Papain-like protease phenotype PLP precursor protease Protease activity Replication reservoir Respiratory Coronavirus resulting S. cerevisiae SARS-CoV Screen severe shown small molecule suppressor toxic effect virus replication yeast [DOI] 10.1371/journal.pone.0028479 PMC 바로가기 [Article Type] Research Article