Dominant CD8 + T Cell Nucleocapsid Targeting in SARS-CoV-2 Infection and Broad Spike Targeting From VaccinationSARS-CoV-2 감염에서 우세한 CD8 + T 세포 뉴클레오캡시드 표적화 및 백신 접종으로 인한 광범위한 스파이크 표적화Immunology Published on 2022-02-222022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 진단, 치료법, [키워드] anti-SARS-CoV-2 Anti-spike Antibody Response Antibody responses assays average boost breadth CD8 CD8+ T cells Cellular immune response cellular immunity Coverage COVID-19 COVID-19 symptom COVID-19 vaccine demonstrated density dominant ELISpot assays envelope protein envelope proteins epitope Epitopes evaluated Evaluating flow cytometry greater IFN-γ IFN-γ ELISPOT IL-4 Inclusion magnitude nucleocapsid persistence predicted protective role Receptor binding domain Region regions response responses against SARS-CoV-2 SFC spike spot-forming cell spot-forming cells subset sustained T cell T cell response T cell responses T cells targeting Th1 vaccination Vaccine Viral viral infections while [DOI] 10.3389/fimmu.2022.835830 PMC 바로가기 [Article Type] Immunology
Performances of rapid and connected salivary RT-LAMP diagnostic test for SARS-CoV-2 infection in ambulatory screeningArticle Published on 2022-02-182022-10-04 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 변종, [키워드] 95%CI analyzed collected demonstrated Diagnosis diagnostic Disease prevention dominant Epidemiology evaluated event Genetic variant Health authority individual Infectious-disease diagnostics isothermal amplification Mutation Outpatient Participants performance Population screening positive primer quantitative PCR reference standard required RT-LAMP RT-qPCR Saliva salivary SARS-CoV-2 SARS-CoV-2 detection SARS-COV-2 infection secure specificity Surveillance Swab symptomatic and asymptomatic tested transfer unique [DOI] 10.1038/s41598-022-04826-7 PMC 바로가기 [Article Type] Article
Evaluation of Muscle Mass and Stiffness with Limb Ultrasound in COVID-19 Survivors코로나19 생존자의 사지 초음파로 근육량 및 강성 평가Observational Study Published on 2022-02-172022-09-12 Journal: Frontiers in Endocrinology [Category] COVID19(2023년), MERS, SARS, 임상, 진단, [키워드] adjusted battery catabolic Characteristics COVID - 19 COVID-19 COVID-19 patients cross cut-off described dominant evaluated hospital discharge illnesses individual limb males mass median age multidimensional muscle muscle mass muscle quality Muscle strength muscles Patient performance performed Post-COVID-19 patients preliminary finding reduced Result sarcopenia SARS-CoV-2 pneumonia stiffness survivor Ultrasound [DOI] 10.3389/fendo.2022.801133 PMC 바로가기 [Article Type] Observational Study
Comparing real-life effectiveness of various COVID-19 vaccine regimens during the delta variant-dominant pandemic: a test-negative case-control study델타 변이가 우세한 대유행 동안 다양한 COVID-19 백신 요법의 실제 효과 비교: 테스트-음성 사례-대조군 연구Coronaviruses Published on 2022-02-162022-09-10 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adjusted age B.1.617.2 BNT162b2 booster case-control study ChAdOx1 ChAdOx1 nCoV-19 Chain Reaction Clinical characteristics conducted controls CoronaVac coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pandemic COVID-19 vaccine delta variant demonstrated disease dominant dose effective Effectiveness enrolled followed by highest increase in individual individuals less nasopharyngeal nCoV polymerase chain polymerase chain reaction real-life receiving regimen respiratory RT-PCR severe acute respiratory syndrome Coronavirus Thailand Vaccine vaccine dose vaccine doses variant virus [DOI] 10.1080/22221751.2022.2037398 PMC 바로가기 [Article Type] Coronaviruses
The mutational landscape of SARS-CoV-2 variants diversifies T cell targets in an HLA-supertype-dependent mannerSARS-CoV-2 변이체의 돌연변이 환경은 HLA 수퍼타입 의존 방식으로 T 세포 표적을 다양화합니다Article Published on 2022-02-162022-09-11 Journal: Cell Systems [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] analyzed CD8 country COVID-19 delta variant dominant driven by epitope Epitopes expressing HLA HLA-B HLA-B allele HLA-B alleles Immunity immunodominant individual mass vaccination mutants Mutation pandemic peptide population level predicted prevalent proline proteome residue RNA SARS-CoV-2 SARS-CoV-2 genome assemblies SARS-CoV-2 variant supertype T cell T cell epitope T cell epitopes target vaccination variant variants [DOI] 10.1016/j.cels.2021.09.013 PMC 바로가기 [Article Type] Article
Hyperbaric oxygen treatment for long coronavirus disease-19: a case reportCase Report Published on 2022-02-152022-10-30 Journal: Journal of Medical Case Reports [Category] Coronavirus, COVID19(2023년), MERS, SARS, [키워드] athletic Blood Brain brain region Cardiopulmonary Case report cerebral blood flow cognitive Cognitive function coronavirus coronavirus disease correlated COVID COVID-19 diffusion dominant Effect executive fatigue functions HBOT healthy hyperbaric oxygen Hyperbaric oxygen therapy hypercoagulability hypoxia impairment improvement include increase increase in individual induce Infection Inflammatory response information Long COVID magnetic resonance imaging memory Neuroinflammation oxygen Oxygen therapy pandemic pathophysiology physical physical capacity physical measurement potential mechanism randomized control study reduce responsible risk SARS-CoV-2 severe coronavirus disease suffered Symptom syndrome Tensor treated Treatment vessel [DOI] 10.1186/s13256-022-03287-w PMC 바로가기 [Article Type] Case Report
Structural basis for SARS-CoV-2 Delta variant recognition of ACE2 receptor and broadly neutralizing antibodiesACE2 수용체 및 광범위 중화 항체의 SARS-CoV-2 Delta 변이체 인식을 위한 구조적 기반Article Published on 2022-02-152022-09-10 Journal: Nature Communications [Category] COVID19(2023년), MERS, SARS, 변종, 유전자 메커니즘, 진단, [키워드] ACE2 ACE2 binding ACE2 receptor affinity Antibody neutralization antigenic binding circulating complex conformational conformational state contribute cryo-EM Cryo-EM analysis cryo-EM structure cryo-EM structures Cryoelectron microscopy Delta delta variant destabilized dominant effective Engagement FIVE identify immune induce Interaction lead mAbs mechanism Mutation Neutralizing neutralizing antibody pathogenicity RBD RBM receptor SARS-CoV-2 sensitivity shedding Spread T478K tested Transmission Viral proteins [DOI] 10.1038/s41467-022-28528-w PMC 바로가기 [Article Type] Article
Antiviral/antibacterial biodegradable cellulose nonwovens as environmentally friendly and bioprotective materials with potential to minimize microplastic pollution항바이러스/항균 생분해성 셀룰로오스 부직포는 미세플라스틱 오염을 최소화할 수 있는 환경 친화적이고 생물 보호적인 소재입니다.Article Published on 2022-02-152022-09-11 Journal: Journal of hazardous materials [Category] COVID19(2023년), SARS, 치료제, [키워드] activity Antibacterial Antiviral Aquatic ecosystems biodegradability Cellulose component coronavirus SARS-CoV-2 COVID-19 COVID-19 crisis crisis demonstrated dominant Environment equipment Face mask Face masks grafting guanidine hydrophobicity lack Mask Microstructure Neomycin neomycin sulfate Personal protective equipment Polymer Polypropylene PPE Protective raised reagent robust SARS-CoV-2 sulfate textiles Textiles. virucidal [DOI] 10.1016/j.jhazmat.2021.127391 PMC 바로가기 [Article Type] Article
High diversity in Delta variant across countries revealed by genome‐wide analysis of SARS‐CoV‐2 beyond the Spike protein스파이크 단백질을 넘어 SARS-CoV-2의 게놈 전체 분석에 의해 밝혀진 국가 간 Delta 변이체의 높은 다양성Article Published on 2022-02-142022-09-10 Journal: Molecular Systems Biology [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료법, [키워드] Alpha Alpha variant Amino acid Analysis Beta Bioinformatics analysis contagious coronavirus country Delta delta variant dominant feature focus genomes highlight identify life list Microbiology, Virology & Host Pathogen Interaction Missense mutation Mutation mutations neutralization nucleocapsid other variant other variants pathogenic performed Prevalence prevalent prevalent strain Protein Proteins proteome public health reduced SARS‐CoV‐2 SARS‐CoV‐2 genome SARS‐CoV‐2 genomes SARS‐CoV‐2 protein SARS‐CoV‐2 proteins SARS‐CoV‐2 spike Spike protein susceptibility systematic analysis the Spike Transmissibility Vaccines Viral viral loads while [DOI] 10.15252/msb.202110673 PMC 바로가기 [Article Type] Article
Detection of SARS-CoV-2 in urban stormwater: An environmental reservoir and potential interface between human and animal sources도시 우수에서 SARS-CoV-2 감지: 환경 저수지 및 인간과 동물 출처 간의 잠재적 인터페이스Article Published on 2022-02-102022-09-11 Journal: The Science of the total environment [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] Affect Characteristics city collected Concentration concentrations confirmed case confirmed COVID-19 case Contamination coronavirus correlated correlation COVID-19 detectable detection determine dominant E gene facilitate Factor fecal Fecal contamination Future hazard Human investigated microbial Microbial source tracking occurred one health pathway Pathways persistence Potential potential transmission SARS-CoV-2 SARS-CoV-2 E gene SARSCoV-2 significantly stormwater target gene the SARS-CoV-2 Transmission urban Urban runoff. viral outbreak virus Virus concentrations wastewater while [DOI] 10.1016/j.scitotenv.2021.151046 PMC 바로가기 [Article Type] Article