Genetic diversity and complexity of Plasmodium falciparum infections in the microenvironment among siblings of the same household in North-Central Nigeria북중부 나이지리아의 같은 가정 내 형제들 사이에서의 플라스모디움 팔시파룸 감염의 유전적 다양성과 복잡성Research Published on 2020-09-162024-08-11 Journal: Malaria Journal [Category] 말라리아, [키워드] genetic diversity malaria Micro-environment MSP-2 multiplicity of infection Nigeria Plasmodium falciparum Transmission intensity [DOI] 10.1186/s12936-020-03415-1 PMC 바로가기 [Article Type] Research
Genetic diversity of hepatitis B virus in Yunnan, China: identification of novel subgenotype C17, an intergenotypic B/I recombinant, and B/C recombinantsArticle Published on 2020-09-012023-06-13 Journal: The Journal of General Virology [Category] B형 간염, [키워드] Chronic Hepatitis B genetic diversity genotype and subgenotype Hepatitis B virus Yunnan [DOI] 10.1099/jgv.0.001147
Genomic diversity and evolution, diagnosis, prevention, and therapeutics of the pandemic COVID-19 diseaseGenomics Published on 2020-09-012022-10-28 Journal: PeerJ [Category] COVID-19, [키워드] acquisition acute respiratory syndrome Amino acid Analysis annotation Antigen available data candidate candidate drugs caused cleavage site Comprehensive coronavirus coronavirus disease COVID-19 COVID-19 disease COVID-19 patients Deletion diagnose Diagnosis diagnostic diagnostics effective Evolution functional furin genetic diversity Genome evolution genomic glycoprotein insertion knowledge Laboratory management mutations nucleotides pandemic pathogenic polybasic predicted real-time RT-PCR released Research RNA virus SARS-CoV-2 SARS-CoV-2 genome shown Substitution Surveillance therapeutic therapeutic agent Therapeutics therapy Trial trials Vaccine Vaccines viral infection virus whole-genome Wuhan, China zoonotic [DOI] 10.7717/peerj.9689 PMC 바로가기 [Article Type] Genomics
Epidemiology and genetic diversity of zoonotic pathogens in urban rats (Rattus spp.) from a subtropical city, Guangzhou, southern ChinaArticle Published on 2020-08-012023-06-22 Journal: Zoonoses and Public Health [Category] 조류인플루엔자, [키워드] Bartonella genetic diversity HEV Leptospira urban rats zoonotic diseases [DOI] 10.1111/zph.12717
Implications of SARS-CoV-2 genetic diversity and mutations on pathogenicity of the COVID-19 and biomedical interventionsReview article Published on 2020-08-012022-10-05 Journal: Journal of Taibah University Medical Sciences [Category] 변종, [키워드] “COVID-19 Affect analysed Antiviral antivirals approach article caused Chemotherapy claimed Coronavirus disease 2019 COVID-19 COVID-19 pandemic Critical eligible European Evolution Factor filtered FIVE genetic diversity health emergency implication Intervention investigated Measures medical subject heading molecular mutant Mutation non-structural protein objective pathogenicity RdRP Result RNA-dependent RNA polymerase S protein SARS-CoV-2 serodiagnosis serodiagnostic Surveillance the S protein Transmission Treatment USA vaccination Vaccine development Vaccines virulence [DOI] 10.1016/j.jtumed.2020.06.005 [Article Type] Review article
The Enigma of Low COVID-19 Fatality Rate in India인도의 낮은 COVID-19 치사율의 수수께끼Genetics Published on 2020-07-282022-08-13 Journal: Frontiers in Genetics [Category] 유전자 메커니즘, [키워드] ACE2 receptors acute respiratory syndrome coronavirus Alter angiotensin converting enzyme 2 average BCG vaccination Betacoronavirus caused circulating city coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 death environmental factor environmental factors Epigenetic evidenced Factor Factors Fatality rate genetic diversity Genetic polymorphism genetic polymorphisms Guangdong Health Organization high temperature Host Humidity hypothese ICU admission immune responses include India Indian population Innate immunity killer cell immunoglobulin-like receptors less lowest mechanical ventilation micro RNA microRNA Mutation offer pandemic pathogen Perspective Pneumonia Rate reducing reported respiratory responsible SARS-CoV-2 SARS-CoV-2 strains severity strain susceptibility the disease Transmissibility Transmission viability virulence virus WHO World Health Organization Wuhan [DOI] 10.3389/fgene.2020.00854 PMC 바로가기 [Article Type] Genetics
Evolutionary origins of the SARS-CoV-2 sarbecovirus lineage responsible for the COVID-19 pandemic Research Published on 2020-07-282022-10-05 Journal: Nature Microbiology [Category] SARS, 유전자 메커니즘, 치료기술, [키워드] appear approach bat bat virus Bayesian China circulating coronavirus SARS-CoV-2 COVID-19 pandemic Divergence estimate Evolutionary rate genetic diversity HCoV-OC43 highest human ACE2 independent Lineage MERS-CoV Phylogenetic question receptor-binding motif receptors Recombination Region responsible sarbecovirus SARS-CoV SARS-CoV-2 shown specificity the SARS-CoV-2 viruses [DOI] 10.1038/s41564-020-0771-4 [Article Type] Research
Validation of Variant Assembly Using HAPHPIPE with Next-Generation Sequence Data from VirusesArticle Published on 2020-07-142022-10-28 Journal: Viruses [Category] COVID-19, SARS, [키워드] Analysis assembly bioinformatics Consensus consensus sequence dataset datasets de novo Genetic genetic diversity gp120 greater Haplotype haplotypes HCV HIV identify Intra-host diversity Metrics NGS offer performed platform precluded produced provide quantification SARS-CoV-2 sequence Sequencing significantly Simulation validation variants Variation viruses [DOI] 10.3390/v12070758 PMC 바로가기 [Article Type] Article
nCOVID-19 Pandemic: From Molecular Pathogenesis to Potential Investigational TherapeuticsCell and Developmental Biology Published on 2020-07-102022-10-31 Journal: Frontiers in Cell and Developmental Biology [Category] COVID-19, [키워드] acute respiratory syndrome Affect analyzed antiviral activity antiviral drug Clinical efficacy Combination coronavirus Corticosteroids COVID-19 eculizumab Efficacy environmental factor Epidemic evaluate exhibited Favipiravir genetic diversity Good Hydroxychloroquine immunomodulators inhibitor molecular monoclonal nCOVID-19 novel coronavirus disease Pathogenesis Patient patients polyclonal antibody Potential RdRP RdRp inhibitors Remdesivir RNA-dependent RNA polymerase SARS-CoV-2 temperature therapeutic option Therapeutics Transmission treat umifenovir virus widespread worldwide pandemic Wuhan, China [DOI] 10.3389/fcell.2020.00616 PMC 바로가기 [Article Type] Cell and Developmental Biology
Emerging phylogenetic structure of the SARS-CoV-2 pandemicRapid Communication Published on 2020-07-102022-10-28 Journal: Virus Evolution [Category] COVID-19, [키워드] accumulating approach cell entry Continuous COVID-19 Efficacy effort epidemiological Epidemiology Europe European event example Factors gene region genetic diversity globe growth humans increase in increasingly MONITOR more difficult Mutation occur pandemic phylodynamic phylodynamics Phylogenetic question responsible reveal SARS-CoV-2 SARS-CoV-2 lineage significantly Spread Structure Support the SARS-CoV-2 trajectory viral replication virus virus demography [DOI] 10.1093/ve/veaa082 PMC 바로가기 [Article Type] Rapid Communication