Reduced T-cell response following a third dose of SARS-CoV-2 vaccine in infection-naïve people living with HIVArticle Published on 2022-12-012023-07-10 Journal: The Journal of Infection [Category] COVID19(2023년), [키워드] Antibody responses Breakthrough infection cellular COVID-19 vaccine HIV humoral immune response neutralisation omicron people living with HIV SARS-CoV-2 mRNA vaccine third dose [DOI] 10.1016/j.jinf.2022.09.006 PMC 바로가기
Safety and immunogenicity of inactivated SARS-CoV-2 vaccines in people living with HIVHIV 보균자에서 비활성화된 SARS-CoV-2 백신의 안전성 및 면역원성Observational Study Published on 2022-12-012022-09-12 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 임상, 진단, [키워드] adverse event age Analysis binding domain booster dose CD4 CD4 count CD4 counts Cell COVID-19 declined Efficacy enrolled evaluated Factor Frequency Gender geometric GMT healthy control healthy controls HIV humoral humoral immune response IgG immune immune response Immunocompromised in both groups inactivated Inactivated vaccine less MBC memory B occurred Patient PLWH predicted prospective observational study reduced remained reported response responses robust Safety SARS-CoV-2 SARS-CoV-2 vaccine Serious Adverse Event Seven significantly vaccination Viral load with HIV [DOI] 10.1080/22221751.2022.2059401 PMC 바로가기 [Article Type] Observational Study
Antibody titers and neutralizing activity in cases of COVID-19 after a single dose of vaccinationArticle Published on 2022-12-012022-11-15 Journal: Journal of infection and chemotherapy : official j [Category] COVID19(2023년), SARS, 진단, [키워드] acute respiratory syndrome antibody Antibody titers coronavirus coronavirus disease Course COVID-19 Efficacy examined first vaccination immune response Infection Neutralizing activity Neutralizing titer onset of disease Patient SARS-CoV-2 shown single dose vaccination [DOI] 10.1016/j.jiac.2022.08.026 PMC 바로가기
The differential immune response in mild versus fatal SARS-CoV2 infectionArticle Published on 2022-12-012023-07-10 Journal: Annals of diagnostic pathology [Category] COVID19(2023년), [키워드] COVID-19 fatal disease immune response Mild disease SARS-CoV2 [DOI] 10.1016/j.anndiagpath.2022.152032 PMC 바로가기
Association of trace element status in COVID-19 patients with disease severityResearch article Published on 2022-12-012022-10-05 Journal: Journal of trace elements in medicine and biology [Category] COVID19(2023년), SARS, 변종, [키워드] Anti-inflammatory antioxidant clinical condition clinical symptom conditions coronavirus coronavirus disease COVID-19 COVID-19 patient COVID-19 severity Critical Cu death died disease severity evaluated Fe four group groups I immune response immune system Infection Mg Mild symptom new SARS-CoV-2 no difference Patient reduce risk SARS-COV-2 infection Se Serum level severity severity of symptoms shown significant difference the patient Trace element trace elements Zn [DOI] 10.1016/j.jtemb.2022.127055 [Article Type] Research article
Immunogenicity and safety of BNT162b2 mRNA vaccine in Chinese adults: A phase 2 randomised clinical trialArticle Published on 2022-12-012022-10-06 Journal: The Lancet Regional Health - Western Pacific [Category] 진단, [키워드] acute respiratory syndrome Administered Adults adverse event AEs age Analysis assessment assigned BNT162b2 BNT162b2 mRNA BNT162b2 mRNA vaccine China Chinese clinical trial Complete Completed conducted coronavirus COVID-19 development dose double-blind Efficacy and safety enrolled Follow-up geometric mean titer GMT GMTs Han Chinese healthy immune response immunogenicity immunogenicity endpoint Inc independent individual injection intramuscular Intramuscular injection investigators Laboratory parameters management messenger Messenger RNA Mild moderate mRNA vaccine Neutralising Antibodies neutralising antibody of BNT162b2 participant Participants pharmaceutical Placebo placebo-controlled trial randomisation randomised Randomly reactogenicity receive recipients recruited reduced remained reported resolved Result robust Safety SARS-CoV-2 SARS-CoV-2 variant SCR second dose sera serious AE seroconversion rate severity Shanghai Sponsor statisticians stratified T-cell Response the placebo group Tolerability Treatment Trial utilised vaccination vaccine administration were blinded [DOI] 10.1016/j.lanwpc.2022.100586 PMC 바로가기 [Article Type] Article
Novel bridge multi-species ELISA for detection of SARS-CoV-2 antibodiesArticle Published on 2022-12-012023-07-10 Journal: Journal of Immunological Methods [Category] COVID19(2023년), [키워드] Bridge multi-species ELISA immune response SARS-CoV-2 Spike protein [DOI] 10.1016/j.jim.2022.113365 PMC 바로가기
Distinct immune responses in the early phase to natural SARS-CoV-2 infection or vaccinationArticle Published on 2022-12-012022-11-15 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 진단, [키워드] acute phase acute respiratory syndrome analyzed antibody Antibody Response coronavirus cytokine cytokine expression cytokine level Cytokines dose early phase elicited expression healthy IgA antibody immune response immunization implication inactivated Inactivated vaccine Inactivated Vaccines infected individuals natural infection nucleocapsid postvaccination Protein Reinfection response SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike SARS-CoV-2 vaccine SARS-CoV-2 vaccines serological significant differences two groups vaccination Vaccines variety viral infection [DOI] 10.1002/jmv.28034 PMC 바로가기
Differential transcriptomic landscapes of multiple organs from SARS-CoV-2 early infected rhesus macaquesSARS-CoV-2 초기 감염된 붉은털 원숭이의 여러 기관의 차등 전사체 풍경Article Published on 2022-12-012022-09-11 Journal: Protein & Cell [Category] COVID19(2023년), SARS, 유전자 메커니즘, 진단, [키워드] accompanied analyzed Angiogenesis cause Central nervous system cerebral cortex changes in clinical complications clinical manifestation clinical manifestations CNS Coagulation controls drastic dysregulation early infection elevated Encephalitis evidenced examined exhibited expression expressions Factor fibrosis function Genes hyperinflammatory state immune response immune responses infected with SARS-CoV-2 Infection Inflammation inflammation response Inflammatory factor inflammatory factors mechanism multiple organ neuropilin 1 NRP1 organs positive positive feedback post infection provide receptor rhesus rhesus macaque right ventricle SARS-CoV-2 SARS-COV-2 infection significantly tissue tissues transcriptomic transcriptomic alteration Transmission up-regulated upregulation Viral viral encephalitis [DOI] 10.1007/s13238-022-00915-5 PMC 바로가기 [Article Type] Article
A review post-vaccination SARS-CoV-2 serological test: Method and antibody titer responseArticle Published on 2022-12-012022-11-15 Journal: Analytical biochemistry [Category] COVID19(2023년), SARS, 진단, [키워드] Antibody titer chemiluminescent immunoassay CLIA CMIA Convalescent plasma therapy Coronavirus disease 2019 COVID-19 Efficacy effort ELISA human donor identify immune response Immune titer immunoassay Lateral LFIA pandemic plaque PRNT reactive SARS-CoV-2 serological serological test Serologist Serologist method serology test Test Vaccine Vaccines [DOI] 10.1016/j.ab.2022.114902 PMC 바로가기