Comparison of two assays to detect IgG antibodies to the receptor binding domain of SARS‑CoV‑2 as a surrogate marker for assessing neutralizing antibodies in COVID-19 patientsCOVID-19 환자에서 중화 항체를 평가하기 위한 대리 표지자로서 SARS-CoV-2의 수용체 결합 도메인에 대한 IgG 항체를 검출하기 위한 두 가지 분석법의 비교Article Published on 2021-08-012022-09-11 Journal: International Journal of Infectious Diseases [Category] MERS, SARS, 바이오마커, 진단, 치료기술, [키워드] acute illness acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibody Cohort coronavirus correlated COVID-19 COVID-19 patient detect disease severity FIVE Haemagglutination assay IgG antibody Indicator Kinetics marker mild illness moderate NAb NAbs Neutralization assay neutralization test Neutralizing antibodies neutralizing antibody Patient persistence positively correlated Receptor binding domain Reinfection respiratory SARS-CoV-2 sensitivity Seven severe acute respiratory syndrome Coronavirus severity severity of illness significantly Spearman specificity surrogate surrogate neutralization assay surrogate virus neutralization test sVNT titre virus neutralization test were assessed [DOI] 10.1016/j.ijid.2021.06.031 PMC 바로가기 [Article Type] Article
Cancer Patients’ Willingness to Take COVID-19 Vaccination: A Nationwide Multicenter Survey in KoreaArticle Published on 2021-08-012022-10-31 Journal: Cancers [Category] COVID-19, [키워드] absence analogue Cancer cancer diagnosis cancer patient Cancer patients concerning Coronavirus disease 2019 COVID-19 COVID-19 vaccination COVID-19 vaccine COVID-19 vaccines disease status domains Factor Factors FIVE Gender Health status healthy Hesitancy identify Influenza Korean male malignancy morbidity and mortality multicenter obesity Older age participated Patient physician positively correlated Predictive predictor promote receive recommendation reduced reported SARS-CoV-2 scale simple survey vaccination Vaccine Vaccine hesitancy Visual [DOI] 10.3390/cancers13153883 PMC 바로가기 [Article Type] Article
Transcriptome Analysis of Peripheral Blood Mononuclear Cells Reveals Distinct Immune Response in Asymptomatic and Re-Detectable Positive COVID-19 Patients말초 혈액 단핵 세포의 전사체 분석, 무증상 및 재검출 가능한 COVID-19 환자에서 뚜렷한 면역 반응을 나타냄Immunology Published on 2021-07-292022-09-11 Journal: Frontiers in Immunology [Category] SARS, 유전자 메커니즘, 치료기술, [키워드] Activation addition Analysis assist Asymptomatic asymptomatic patient asymptomatic patients Clinical management co-expression complement Complement activation comprehensive analysis coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 disease COVID-19 patient disease control enrichment enrichment analysis gene co-expression network gene set enrichment analysis GSEA Host immune response hyper-inflammatory immune response IFN response immune response immune responses Immunotherapy Influenza influenza infection mononuclear cell mononuclear cells MOST NF-κB Patient patients PBMC PBMCs performed peripheral Peripheral blood Peripheral blood mononuclear cells positive positively correlated progression Re-detectable positive Recovered COVID-19 patients recovered patients response SARS-CoV-2 symptomatic symptomatic patient Symptomatic patients the disease TNFα transcriptomic profile transcriptomic profiles turquoise module weaker immune response WGCNA [DOI] 10.3389/fimmu.2021.716075 PMC 바로가기 [Article Type] Immunology
Exploring the factors associated with coronaphobia among physicians during the COVID-19 outbreak in EgyptResearch Published on 2021-07-292022-10-31 Journal: The Egyptian Journal of Neurology, Psychiatry and Neurosurgery [Category] COVID-19, [키워드] Anxiety conducted Coronaphobia COVID-19 COVID-19 outbreak COVID-19 virus cross-sectional death Depression depressive symptom Egypt evaluate Factor fear females HADS infected with COVID-19 Infection measure Mental not differ outbreak Personal protective equipment physical physician Physicians positively correlated PPE receiving reported Result routine scale Symptom Symptoms virus infection [DOI] 10.1186/s41983-021-00357-6 PMC 바로가기 [Article Type] Research
Longitudinal influence of COVID-19-related stress on sexual compulsivity symptoms in Chinese undergraduatesResearch Published on 2021-07-272022-10-27 Journal: BMC Psychiatry [Category] COVID-19, [키워드] Anxiety Anxiety sexual compulsivity symptom association associations Chinese coronavirus disease COVID-19 Depression disorders event impacted Isolation longitudinal mental health pandemic Participants physical positively correlated predict recruited respond Result SCS Stress Symptom time [DOI] 10.1186/s12888-021-03369-x PMC 바로가기 [Article Type] Research
Longitudinal influence of COVID-19-related stress on sexual compulsivity symptoms in Chinese undergraduatesResearch Published on 2021-07-272022-10-27 Journal: BMC Psychiatry [Category] Coronavirus, COVID-19, SARS, [키워드] Anxiety Anxiety sexual compulsivity symptom association associations Chinese coronavirus disease COVID-19 Depression disorders event impacted Isolation longitudinal mental health pandemic Participants physical positively correlated predict recruited respond Result SCS Stress Symptom time [DOI] 10.1186/s12888-021-03369-x PMC 바로가기 [Article Type] Research
Non-thyroidal illness syndrome and SARS-CoV-2-associated multisystem inflammatory syndrome in childrenOriginal Article Published on 2021-07-262022-10-30 Journal: Journal of Endocrinological Investigation [Category] COVID-19, SARS, [키워드] abnormality absence Alter association catabolic characterized children children’s health cholesterol Combination component correlated COVID-19 disease Critical defined disease severity Follow-up HDL help hospital Inflammation Inflammatory insulin resistance involved IQR management median age MIS-C Multisystem inflammatory syndrome Non-thyroidal illness syndrome organ organ damage Overall Severity Score patients PC1 PC2 PC3 PCA pediatric positively correlated principal component analysis profile profiles Prognosis Result SARS-CoV-2 severity Severity Score subject syndrome thyroid function to define triglycerides TSH turn variable was performed [DOI] 10.1007/s40618-021-01647-9 PMC 바로가기 [Article Type] Original Article
Lung Ultrasound Examination in Patients with SARS-CoV-2 Infection: Multicenter StudyArticle Published on 2021-07-232022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] age ambulatory patients average Care characterized chest sonography Computed tomography consolidations contributed COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 patients diagnostic Diagnostic method examination High-resolution hospitalized patient hospitalized patients HRCT indicated infected patients interstitial interstitial pneumonia lung LUS males measure multicenter study Older Patient patients Pneumonia positively correlated SARS-CoV-2 Sensitivity and specificity significantly more syndrome Ultrasound was performed [DOI] 10.3390/jcm10153255 PMC 바로가기 [Article Type] Article
RBM15-mediated N6-methyladenosine modification affects COVID-19 severity by regulating the expression of multitarget genesRBM15 매개 N6-메틸아데노신 변형은 다중 표적 유전자의 발현을 조절하여 COVID-19 중증도에 영향을 미칩니다Article Published on 2021-07-232022-09-11 Journal: Cell Death & Disease [Category] 유전자 메커니즘, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Affect Alter Analysis biological processe Biomarkers cell death characterized coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 severity death disease severity elevated expression expression level expression levels Genes Host immune response in vitro Infection Infectious diseases Inflammatory response knockdown lymphocyte Lymphocytes lymphopenia mechanism methyltransferase Microarray Microarray analyses mild COVID-19 patients Modification modulated Multiorgan N6-methyladenosine performed positively correlated profile programmed cell death RBM15 reduced regulated respiratory SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus severe and mild COVID-19 patients severe coronavirus disease severe patients significantly suppressed Symptom target Treatment treatment of COVID-19 [DOI] 10.1038/s41419-021-04012-z PMC 바로가기 [Article Type] Article
Predicting Pharmacist Intention to Contribute to COVID-19 Management at the Community Level: A Cross-Sectional Survey StudyPublic Health Published on 2021-07-222022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, SARS, [키워드] addition Alpha association combating Community contribute correlation COVID-19 COVID-19 infection COVID-19 pandemic cross-sectional demonstrated determine expected explained female identify Intention key factor majority management mean score measure Multiple linear regression Outbreak management pandemic participant Pearson Pharmacist pharmacist (community) positive positively correlated predict predictors public health public health emergency questionnaire reliability response Specific survey the theory of planned behavior Validity variable variables was used were measured were used [DOI] 10.3389/fpubh.2021.653335 PMC 바로가기 [Article Type] Public Health