IFN-γ + cell response and IFN-γ release concordance after in vitro SARS-CoV-2 stimulation시험관 내 SARS-CoV-2 자극 후 IFN-γ + 세포 반응 및 IFN-γ 방출 일치Article Published on 2021-12-012022-09-11 Journal: European Journal of Clinical Investigation [Category] SARS, 치료법, [키워드] Analysis anti-SARS-CoV-2 anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 antibody case-control study CD4 T-cell CD8 CD8 T-cell Cell cellular Cellular immune response cellular response Concordance convalescent COVID-19 cross-sectional determine ELISA exposed healthcare workers. flow cytometry greater HCW HCWs healthcare healthcare worker Healthcare workers IFN-γ immune in vitro increased risk individual Infection less magnitude proportion protective immunity quantification SARS-CoV-2 SARS-CoV-2-infected patients Stimulation susceptibility Symptoms T cell T cells T-cell Response uninfected Viral protein Viral proteins [DOI] 10.1111/eci.13636 PMC 바로가기 [Article Type] Article
Sandwich/competitive immuno-sensors on micro-interface for SARS-CoV-2 neutralizing antibodiesSARS-CoV-2 중화 항체용 마이크로 인터페이스의 샌드위치/경쟁 면역 센서Article Published on 2021-12-012022-09-11 Journal: Analytica chimica acta [Category] MERS, SARS, 진단, 치료기술, [키워드] analyzed Antigen comparable conducted COVID-19 demonstrated detect Efficacy fluorescent immunoassay interface microfluidic microsphere NAb NAbs Neutralizing antibodies quantification RBD Receptor binding domain robust Sandwich Sandwich/competitive immuno-sensor. SARS-CoV-2 SARS-CoV-2 nAbs SARS-CoV-2 neutralizing antibodies SARS-CoV-2 neutralizing antibody sensitivity serum sample vaccinated individuals Vaccine Vaccine development vaccine efficacy [DOI] 10.1016/j.aca.2021.339144 PMC 바로가기 [Article Type] Article
Multicentric evaluation of a novel point of care electrochemical ELISA platform for SARS-CoV-2 specific IgG and IgM antibody assaySARS-CoV-2 특이적 IgG 및 IgM 항체 분석을 위한 새로운 현장 진료 전기화학 ELISA 플랫폼의 다심 평가Article Published on 2021-12-012022-09-11 Journal: Journal of virological methods [Category] SARS, 진단, 치료기술, [키워드] antibody clinical samples Concentration COVID-19 COVID-19 pandemic COVID-19 vaccination current diagnostics Disposable test strips EDTA Electrochemistry ELISA epidemiological survey epidemiological surveys FDA IgG and IgM IgG/IgM antibody IgM antibody monoclonal antibody New performed platform point of care point-of-care Printed electrodes produced quantification Quantitative SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody Sensitivity and specificity serum samples spike spike glycoprotein vaccination Whole blood [DOI] 10.1016/j.jviromet.2021.114275 PMC 바로가기 [Article Type] Article
COVID-19 infection localization and severity grading from chest X-ray images흉부 엑스레이 이미지에서 등급을 매기는 COVID-19 감염 위치 및 심각도Article Published on 2021-12-012022-09-11 Journal: Computers in biology and medicine [Category] SARS, 변종, 치료기술, [키워드] addition annotation approach chest radiographic chest X-ray Chest X-ray image coefficient Convolutional neural networks coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 infection COVID-19 infections COVID-19 pneumonia COVID-19 samples CXR dataset deep deep learning diagnose diagnosis of COVID-19 Dice Effect experiment Healthcare system Healthcare systems Infection Infection Segmentation Intersection iterative learning lung Lung segmentation Mask network Neural Numerous overfitting Patient performed Pneumonia Prevent Pyramid quantification reached Repository required Segmentation Sensitivity and specificity severity Spread the disease tissues union was performed with infection [DOI] 10.1016/j.compbiomed.2021.105002 PMC 바로가기 [Article Type] Article
Correlation of dried blood spots and plasma for quantification of Immunoglobulin (IgG) against Receptor binding domain and full length spike protein of SARS-CoV-2Comparative Study Published on 2021-11-302022-10-04 Journal: Journal of virological methods [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] binding domain Blood correlation dried blood spot Dried blood spots full length Full length spike protein full-length spike protein IgG Immunoglobulin (IgG) plasma Pragmatic quantification Receptor binding domain SARS-CoV-2 SARS-CoV-2 IgG antibodies SARS-COV-2 infection Spike protein [DOI] 10.1016/j.jviromet.2021.114394 PMC 바로가기 [Article Type] Comparative Study
Natural Compounds as Target Biomolecules in Cellular Adhesion and Migration: From Biomolecular Stimulation to Label-Free Discovery and Bioactivity-Based IsolationReview Published on 2021-11-262022-10-28 Journal: Biomedicines [Category] COVID-19, [키워드] adhesion Affect affecting Anti-inflammatory anticancer Biomolecule biosensors CAM can be used Cell Cell adhesion cellular classical Compound concerning Effect Effects Evidence experiment faster fungi Gene Expression greater Health highlighting integrin Isolation knowledge mechanism metabolite metabolites Migration movement natural natural compound plant plants preparation quantification SARS-CoV-2 SARS-CoV-2 treatment signaling pathway Stimulation surface receptor target viability virus [DOI] 10.3390/biomedicines9121781 PMC 바로가기 [Article Type] Review
SARS-CoV-2 detection in wastewater using multiplex quantitative PCR다중 정량 PCR을 사용한 폐수 내 SARS-CoV-2 검출Article Published on 2021-11-252022-09-11 Journal: The Science of the total environment [Category] SARS, 치료기술, 치료법, 치료제, [키워드] amplification Analysis applicability approach calibration curve collected comparable cycle threshold demonstrated detect Environmental surveillance faster handling indicated Laboratory Local multiplex Multiplex assay Multiplex PCR nucleocapsid PCR Proteins qPCR quantification quantitative PCR Reactions reagents reducing required reverse transcription robust robustness RT-qPCR SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 genes target gene Target genes Treatment wastewater water [DOI] 10.1016/j.scitotenv.2021.148890 PMC 바로가기 [Article Type] Article
Site-Specific Labeling of Endogenous Proteins Using CoLDR ChemistryArticle Published on 2021-11-242022-10-29 Journal: Journal of the American Chemical Society [Category] Coronavirus, SARS, [키워드] addition Affect approach binding binding pocket BTK Cell cells Chemical Chemistry CRBN Degradation demonstrated endogenous fluorescent functional inhibit interactions labeling Ligand maintain Modification MONITOR probe Protein quantification SARS-CoV-2 selective shown stability target protein variety [DOI] 10.1021/jacs.1c06167 PMC 바로가기 [Article Type] Article
Anti-Spike SARS-CoV-2 IgG Assessment with a Commercial Assay during a 4-Month Course after COVID-19 VaccinationArticle Published on 2021-11-202022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] administration anti-S Anti-SARS-CoV-2 S Anti-spike antibody assessment Concentration convalescent Course COVID-19 COVID-19 testing COVID-19 vaccine COVID-19 vaccines COVID-19 vaccines booster shot detectable develop DiaSorin dose first dose highest humoral IgG IgG and IgM IgG antibodies IgM response Italy LIAISON naïve vaccinee over participant Pfizer/BioNTech quantification reached remained SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-CoV-2 IgG SARS-CoV-2 IgM significant decrease study cohort subject subjects sustained the antibody utility Vaccine were measured women [DOI] 10.3390/vaccines9111367 PMC 바로가기 [Article Type] Article
Monitoring of SARS-CoV-2 RNA in wastewater as an epidemiological surveillance tool in Mendoza, Argentina아르헨티나 멘도사에서 역학 감시 도구로서의 폐수 내 SARS-CoV-2 RNA 모니터링Article Published on 2021-11-202022-09-11 Journal: The Science of the total environment [Category] SARS, 치료기술, 치료법, [키워드] advance aluminum Analysis applied Concentration COVID-19 COVID-19 case COVID-19 cases diagnosed Epidemiologic surveillance epidemiological epidemiological surveillance Epidemiology exponential growth genetic marker Genetic markers glycol growth Health status increase in individual infections marker MONITOR monitoring N1 and N2 nucleocapsid pandemic plant plateau Polyethylene glycol populations positive correlation quantification RNA isolation RT-qPCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 RNA spatial information Surveillance Treatment Viral load Wastewater-based epidemiology [DOI] 10.1016/j.scitotenv.2021.148887 PMC 바로가기 [Article Type] Article