Receptor-Binding-Motif-Targeted Sanger Sequencing: a Quick and Cost-Effective Strategy for Molecular Surveillance of SARS-CoV-2 Variants수용체 결합 모티브 표적 생어 시퀀싱: SARS-CoV-2 변이체의 분자 감시를 위한 빠르고 비용 효율적인 전략Article Published on 2022-06-292022-09-11 Journal: Microbiology Spectrum [Category] Coronavirus, COVID19(2023년), SARS, 변종, 치료법, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adopted aligned Alpha Alpha variant B.1.1.529 B.1.1.7 B.1.617.2 causative agent changes in CLC Clinical use coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pandemic Critical death Delta delta variant develop disease spread Genome gold gold standard Infection involved Lineage lineages modifications molecular mutate Mutation mutations nasal nasal swab nasal swabs nucleocapsid omicron Omicron variant Omicron variants pandemic prevalent Prevent public health receptor-binding motif Receptor-binding motif (RBM) resource Saliva Sanger sequencing SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants sequence sequences Sequencing severe acute respiratory syndrome Coronavirus Spike protein Spread Strategy Surveillance swab samples the disease variant variant surveillance. variants WGS whole-genome sequencing [DOI] 10.1128/spectrum.00665-22 PMC 바로가기 [Article Type] Article
Detection and Stability of SARS-CoV-2 in Three Self-Collected Specimen Types: Flocked Midturbinate Swab (MTS) in Viral Transport Media, Foam MTS, and Saliva자체 수집한 3가지 표본 유형에서 SARS-CoV-2의 검출 및 안정성: 바이러스 수송 배지, 거품 MTS 및 타액의 무리를 이루는 중비갑개 면봉(MTS)Article Published on 2022-06-292022-09-11 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 치료기술, 치료법, [키워드] 95% CI 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 ambient Analysis children cohorts collected Community Concordance conditions coronavirus COVID-19 detection evaluated exposure to facilitate feasible finding Foam illness illnesses in viral nucleocapsid Open reading frame ORF pandemic positive provided quantification reading respiratory respiratory specimens RT-PCR RT-PCR detection Saliva saliva samples saliva specimen saliva specimens sample collection SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 RNA SARS-CoV-2 testing sensitivity severe acute respiratory syndrome Coronavirus specimen specimen collection spike stability Support Swab temperature tested Transport Transport media transported viral transport media VTM widespread [DOI] 10.1128/spectrum.01033-22 PMC 바로가기 [Article Type] Article
Utilizing Electrochemical-Based Sensing Approaches for the Detection of SARS-CoV-2 in Clinical Samples: A Review임상 샘플에서 SARS-CoV-2 검출을 위한 전기화학 기반 감지 접근 방식 활용: 검토Review Published on 2022-06-292022-09-11 Journal: Biosensors [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 advance Blood clinical clinical samples coronavirus disease Coronavirus disease 2019 Coronavirus-2 COVID-19 detection diagnose diagnostic diagnostic methods diagnostic tests diagnostics early treatment electrochemical biosensor employment equipment healthcare worker Healthcare workers in viral individuals infected individuals Infection Isolation limit limitations microfluidic electrochemical devices miniaturised electrochemical sensor Nasopharyngeal swab operation platform POC point of care point of care (PoC) rapid response readiness respiratory review Saliva SARS-CoV-2 SARS-CoV-2 detection severe acute respiratory syndrome Coronavirus simplicity Spread standard diagnostic test standard diagnostic tests transducing Viral [DOI] 10.3390/bios12070473 PMC 바로가기 [Article Type] Review
Viral RNA Load and Infectivity of SARS-CoV-2 in Paired Respiratory and Oral Specimens from Symptomatic, Asymptomatic, or Postsymptomatic Individuals무증상, 무증상 또는 무증상 개인의 호흡기 및 구강 표본에서 SARS-CoV-2의 바이러스 RNA 부하 및 감염성Article Published on 2022-06-292022-09-11 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 치료기술, [키워드] anterior nares Asymptomatic Asymptomatic individuals asymptomatic patient asymptomatic patients bodily secretions Care care provider classic close contact collected COVID-19 COVID-19 diagnosis Critical diagnosed with COVID-19 diagnostic diagnostic sensitivity diagnostic testing epidemiological FIVE followed by Frequency Health Health care help individual individuals infection with SARS-CoV-2 Infectious virus Infectivity information initial Isolation load molecular nare nares nasopharyngeal oral patients platform positive individual positive individuals provide quarantine respiratory RNA RT-PCR Saliva saliva specimens Sample Sampling frequency SARS-CoV-2 secretion sensitivity specimen specimens Surveillance Swab swabs symptomatic symptomatic patient Symptomatic patients tested The diagnostic sensitivity understanding viral RNA load virus detection virus infectivity virus isolation was determined [DOI] 10.1128/spectrum.02264-21 PMC 바로가기 [Article Type] Article
Saliva changes in composition associated to COVID-19: a preliminary studyCOVID-19와 관련된 타액 조성 변화: 예비 연구Article Published on 2022-06-272022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 바이오마커, 유전자 메커니즘, 임상, 진단, 치료기술, 치료법, [키워드] Activation ACTN4 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 aggregation Anosmia antibody ANXA4 Asymptomatic CA6 can be used caused changes in clinical presentation Clinical presentations composed control group coronavirus coronavirus disease Coronavirus disease 2019 correlated COVID 19 COVID-19 COVID-19 group diagnostic diagnostics disease Diseases downregulation dysgeusia FGB FIVE healthy healthy individual immune response involved Mild mild COVID-19 patient mild COVID-19 patients occur oxidative damage pathophysiology Patient patients patients with COVID-19 Perspective positive Potential biomarker potential biomarkers Protective Protein proteome proteomic study proteomics pulmonary tissue quantification respiratory complication Respiratory complications RT-PCR Saliva saliva samples salivary SARS-CoV 2 separated severe acute respiratory syndrome Coronavirus severe cases severe COVID-19 stimulus taste perception tested TGM3 the disease tissue Treatment two groups upregulation variety viral infection virus [DOI] 10.1038/s41598-022-14830-6 PMC 바로가기 [Article Type] Article
Humoral response to anti-SARS-CoV-2 vaccine in breastfeeding mothers and mother-to-infant antibody transfer through breast milk Research Published on 2022-06-232022-10-05 Journal: NPJ Vaccines [Category] 진단, [키워드] absence Anti-RBD IgG anti-S anti-SARS-CoV-2 anti-SARS-CoV-2 antibody anti-SARS-CoV-2 IgG anti-SARS-CoV-2 vaccine antibody antibody production antibody transfer BNT162b2 vaccine breast milk Breastfeeding Humoral response IgA IgA2 IgG Infants long-lasting magnitude mother mucosal quantified retrieved Saliva serum stimulate swabs transfer vaccination Vaccine vaccine dose [DOI] 10.1038/s41541-022-00499-5 [Article Type] Research
Positivity rates of SAR-CoV-2 infection in orthodontic patients at the orthodontic clinic, University of Illinois ChicagoUniversity of Illinois Chicago 교정 진료소 교정 환자의 SAR-CoV-2 감염 양성률Article Published on 2022-06-232022-09-11 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 치료기술, [키워드] age All participant All participants Asymptomatic average Chain Reaction Chicago collected Community Complete COVID-19 COVID-19 infection COVID-19 transmission COVID-19 vaccination detect females Frequency healthcare providers impacted increased risk Infection information Local male nine orthodontic participant Participants participated Patient patients PCR polymerase chain polymerase chain reaction positive potential risk potential transmission risk Saliva SAR-CoV-2 SARS-CoV-2 SARS-COV-2 infection Sex tested Treatment university vaccination Vaccination Status were recorded [DOI] 10.1371/journal.pone.0270311 PMC 바로가기 [Article Type] Article
Survival of SARS-CoV-2 and bovine coronavirus on common surfaces of living environments생활 환경의 공통 표면에서 SARS-CoV-2 및 소 코로나바이러스의 생존Article Published on 2022-06-232022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 aerosol Aerosols Bovine coronavirus Contamination coronavirus decrease Infectious virus limit of detection living environment Masks nitrile porous Real-time PCR remained RNA Saliva SARS-CoV-2 severe acute respiratory syndrome Coronavirus substrate substrates Survivability survival tested transmitted viral titer viral titers virus were measured [DOI] 10.1038/s41598-022-14552-9 PMC 바로가기 [Article Type] Article
Salivary, serological, and cellular immune response to the CoronaVac vaccine in health care workers with or without previous COVID-19이전 COVID-19 유무에 관계없이 의료 종사자의 CoronaVac 백신에 대한 타액, 혈청 및 세포 면역 반응Article Published on 2022-06-162022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, [키워드] analysed anti-SARS-CoV-2 antibodies Cellular immune response chemiluminescence CoronaVac COVID-19 Delta dose ELISA evaluated Evidence flow cytometry Gamma Health care Health care worker health care workers IFN-γ IFN-γ producing T cells IgA IgG anti-spike antibody IgG antibodies IgG antibody immunized inactivated individual individuals induce infected individuals interferon investigated neutralization test Neutralizing activity post-vaccine response producing provide reactive reduced reference strain response Saliva salivary SARS-CoV-2 SARS-CoV-2 variant serological serum serum antibodies serum antibody specific serum Spike protein T cell T cells T-cell the spike protein uninfected vaccinated individual vaccinated individuals Vaccine variable variants virus virus neutralization test [DOI] 10.1038/s41598-022-14283-x PMC 바로가기 [Article Type] Article
Saliva molecular testing bypassing RNA extraction is suitable for monitoring and diagnosing SARS-CoV-2 infection in childrenRNA 추출을 우회하는 타액 분자 검사는 어린이의 SARS-CoV-2 감염 모니터링 및 진단에 적합Article Published on 2022-06-152022-09-11 Journal: PLoS ONE [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, [키워드] Accuracy addition affecting age antibody Asymptomatic bypassing children collected Community COVID-19 COVID-19 symptom Ct value Ct values diagnosing effective groups hospital IgM Infant Infants Infection investigated molecular nasopharyngeal NP swab Particle positive positive response qPCR test required rescue RNA extraction RT-qPCR test Saliva saliva sample saliva samples SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RNA SARS-CoV-2 variants sensitivity significantly specificity susceptible the mean threshold Vaccine Viral Viral RNA Viral transmission virus [DOI] 10.1371/journal.pone.0268388 PMC 바로가기 [Article Type] Article