Impact of prior infection status on antibody response to the BNT162b2 mRNA COVID-19 vaccine in healthcare workers at a COVID-19 referral hospital in Milan, Italy이탈리아 밀라노의 COVID-19 위탁 병원에서 의료 종사자의 BNT162b2 mRNA COVID-19 백신에 대한 항체 반응에 대한 이전 감염 상태의 영향Article Published on 2021-12-022022-09-11 Journal: Human vaccines & immunotherapeutics [Category] SARS, 진단, 치료기술, [키워드] 95% CI adjusted odds ratio anti-S IgG anti-SARS-CoV-2 Antibody Response BNT162b2 BNT162b2 mRNA BNT162b2 vaccine COVID-19 COVID-19 vaccine detectable dose effective elapsed enrolled Fever first dose HCW HCWs healthcare healthcare worker Healthcare workers hospital humoral Humoral response IgG levels Impact Infection Italy Mild mild to moderate moderate mRNA vaccine naïve subjects occurred of BNT162b2 reactogenicity receive reported risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccination Serious Adverse Event Serious Adverse Events serological serological response Side effect single dose spike IgG subject subjects the median the vaccine Vaccine [DOI] 10.1080/21645515.2021.2002639 PMC 바로가기 [Article Type] Article
Low risk of reinfections and relation with serological response after recovery from the first wave of COVID-19COVID-19의 첫 번째 물결에서 회복된 후 재감염 위험이 낮고 혈청학적 반응과의 관계Article Published on 2021-12-012022-09-12 Journal: European Journal of Clinical Microbiology & Infect [Category] MERS, SARS, 진단, [키워드] age antibody Asymptomatic collected COVID-19 COVID-19 reinfection female First wave Follow-up healthcare IgG IgM response immunization individuals with COVID-19 IQR Italy longitudinal longitudinal study manifested median median age Mild mild infection observation period occurred Outpatient Patient patients Reinfection risk SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 IgG SARS-CoV-2 IgM SARS-CoV-2 reinfection SARS-CoV-2 serology serological serological response serology seronegative seropositive the disease with COVID-19 [DOI] 10.1007/s10096-021-04335-x PMC 바로가기 [Article Type] Article
Evaluation of COVID-19 vaccine response in patients with cancer: An interim analysis암환자의 코로나19 백신 반응 평가: 중간분석Review Published on 2021-12-012022-09-12 Journal: European journal of cancer (Oxford, England : 1990 [Category] MERS, SARS, 진단, [키워드] analysed Analysis anti-SARS-CoV-2 antibody Antibody titre Cancer cohorts collected COVID-19 COVID-19 vaccination COVID-19 vaccine COVID-19 vaccines examined haematological malignancies healthy controls heterogeneous high-risk patient Immunity Immunoglobulin increase in Infection interim analysis Local malignancy Neoplasms Patient patient questionnaire Patients with cancer patients with haematological peer-reviewed Population Preliminary data prophylactic measure receive receiving reduced response risk of COVID-19 S1/S2 Safe SARS-CoV-2 SARS-COV-2 infection second dose Seroconversion serological serological response severe complication Side-effect significantly lower single dose solid cancer solid malignancies Spike protein Support systemic effects the SARS-CoV-2 These data Tumours vaccination [DOI] 10.1016/j.ejca.2021.10.013 PMC 바로가기 [Article Type] Review
The Differences in the Level of Anti-SARS-CoV-2 Antibodies after mRNA Vaccine between Convalescent and Non-Previously Infected People Disappear after the Second Dose—Study in Healthcare Workers Group in PolandArticle Published on 2021-11-272022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] antibodies antibody Concentration conducted convalescent COVID-19 detectable difference ELISA test examined first dose group healthcare worker IgA IgG IgG antibody immune system Immunological response Infection infections Level mRNA non-infected Participants Poland Quantitative SARS-CoV-2 second second dose second vaccination semi-quantitative serological serum significantly study period the SARS-CoV-2 university vaccination Vaccine were measured worker [DOI] 10.3390/vaccines9121402 PMC 바로가기 [Article Type] Article
Community-Based Seroprevalence of SARS-CoV-2 Antibodies following the First Wave of the COVID-19 Pandemic in Jazan Province, Saudi Arabia사우디 아라비아 Jazan 지방의 COVID-19 대유행의 첫 번째 물결에 따른 SARS-CoV-2 항체의 커뮤니티 기반 혈청 유병률Article Published on 2021-11-262022-09-12 Journal: International Journal of Environmental Research an [Category] MERS, SARS, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus age anti-S antibodies anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 antibody asymptomatic infection asymptomatic infections conducted coronavirus COVID-19 decision Decision making Effect ELISA epidemiological female participants global health group Health herd immunity Immunity infections information male Measures mortality rate mortality rates no significant difference Older older population participant Prevalence recruited SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-COV-2 infection Saudi Arabia serological serological data seropositive Seropositivity Seroprevalence severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Spread susceptible These data vaccination Wave [DOI] 10.3390/ijerph182312451 PMC 바로가기 [Article Type] Article
High SARS-CoV-2 Seroprevalence in Rural Peru, 2021: a Cross-Sectional Population-Based Study페루 농촌의 높은 SARS-CoV-2 혈청 유병률, 2021: 횡단면 인구 기반 연구Observation Published on 2021-11-242022-09-10 Journal: mSphere [Category] MERS, SARS, 진단, 치료기술, [키워드] 95% CI 95% confidence interval Affect affected Algorithm altitude Antibody testing avoidance Care chemiluminescence immunoassay CLIA correlations COVID-19 COVID-19 pandemic cross-sectional diagnostics enrolled evade Factor false-positive result False-positive results Health Health care highlighting hot spot incidence Infection information Latin Latin America lead mandatory measure neutralization test performed Peru Population population density Population size populations public health quarantine reactive Region regions reported rural rural population Rural populations SARS-CoV-2 SARS-CoV-2 antibody testing SARS-CoV-2 IgG antibodies SARS-CoV-2 IgG antibody Screening sera serologic serological serology Seroprevalence Spearman specificity Spread Support surface area Surveillance surveillance data sVNT tropical Vaccination strategies Vaccination strategy validation virus neutralization test was done [DOI] 10.1128/mSphere.00685-21 PMC 바로가기 [Article Type] Observation
Usefulness of ELISA Using Total Antibody against Plant-Expressed Recombinant Nucleocapsid Protein of SARS-CoV-2SARS-CoV-2의 식물 발현 재조합 뉴클레오캡시드 단백질에 대한 총항체를 이용한 ELISA의 유용성Research Article Published on 2021-11-242022-09-10 Journal: Microbiology Spectrum [Category] MERS, SARS, 진단, 치료기술, 치료법, [키워드] 2019 novel coronavirus Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibody approaches assays can be used characteristic collected complementary coronavirus coronavirus disease COVID-19 Cutoff diagnosis of COVID-19 Diagnostic method diagnostic value disease Disease progression E. coli ELISA ELISAs enzyme-linked immunosorbent assay enzyme-linked immunosorbent assays Escherichia coli evaluated expressed Genetic highest IgG and IgM immune response immune responses Next-generation sequencing Novel coronavirus novel coronavirus disease nucleic acid nucleocapsid protein nucleoprotein occurred Patient plant plants post-symptom onset present produced PSO receiver operating characteristic recombinant Recombinant nucleocapsid protein respiratory reverse transcription reverse transcription-PCR robust ROC RT-PCR SARS-CoV-2 SD Biosensor sensitivity Sensitivity and specificity Seroconversion seroconversion rate seroconversion rates serological Serological assay Serosurvey serum serum sample serum samples severe acute respiratory syndrome Coronavirus Standard Total total antibody Viral viral nucleic acid [DOI] 10.1128/Spectrum.00672-21 PMC 바로가기 [Article Type] Research Article
Lymphocytopenia and Anti-CD38 Directed Treatment Impact the Serological SARS-CoV-2 Response after Prime Boost Vaccination in Patients with Multiple MyelomaArticle Published on 2021-11-242022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] age Analysis analyzed anti-CD38 anti-CD38-directed therapy anti-SARS-CoV-2 blood sample CD19+ CD19+ B lymphocytes control group correlated disorder Effectiveness eight Factor first vaccination healthy control healthy subjects Heterologous Impact less majority Multiple Multiple myeloma Myeloma Patient patients positive Predictive prevention of COVID-19 Quantitative RBD response responses SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 spike protein antibodies SARS-CoV-2 vaccination SARS-CoV-2 vaccine SARS-CoV-2 vaccines serological serological response shown significantly suggested therapy threshold Treatment vaccination Vaccinations were assessed [DOI] 10.3390/jcm10235499 PMC 바로가기 [Article Type] Article
Seroprevalence of SARS-CoV-2 Antibodies Among Children in School and Day Care in Montreal, Canada캐나다 몬트리올의 학교 및 탁아소 어린이들 사이에서 SARS-CoV-2 항체의 혈청 유병률Research Published on 2021-11-232022-09-10 Journal: JAMA Network Open [Category] MERS, SARS, 변종, 진단, 치료기술, 치료제, [키워드] 95% CI absence adjusted age analyzed baseline Canada Chain Reaction children clinical symptom Clinical symptoms cohort study collected COVID-19 COVID-19 pandemic COVID-19 symptom Day dried blood spot Dried blood spots ELISA enrolled enzyme-linked immunosorbent enzyme-linked immunosorbent assay epicenter estimate Étude exposure exposure to female finding First wave Importance individuals information learning mass vaccination measure Mild mild symptoms minority group Montreal Montreal, Canada MOST objective open outcome parent parents participant Participants Point positive Potential primary schools provide provided question questionnaire Racial Relevance Result RT-PCR SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody School Schools secondary schools selected serological seropositive Seroprevalence setting Sociodemographic tested the mean Transmission vaccination variants of concern were infected white [DOI] 10.1001/jamanetworkopen.2021.35975 PMC 바로가기 [Article Type] Research
Virological and serological kinetics of SARS-CoV-2 Delta variant vaccine breakthrough infections: a multicentre cohort studyMulticenter Study Published on 2021-11-232022-10-04 Journal: Clinical microbiology and infection : the official [Category] COVID19(2023년), MERS, SARS, 변종, 치료법, [키워드] 95% CI acute respiratory syndrome adjusted odds ratio Alter Anti-spike antibody B.1.617.2 Breakthrough infection breakthrough infections Clinical features cohort study conducted coronavirus COVID-19 COVID-19 pandemic Delta delta variant Diagnosis effective effective vaccine faster group hospital in viral individual individuals Infection mRNA vaccine multicentre objective Older age oxygen supplementation Patient PCR cycle Protein Result retrospective cohort study RNA robust SARS-CoV-2 SARS-COV-2 infection serological serological response severe COVID-19 significantly significantly lower Singapore Spread symptomatic the vaccine threshold value titre titres vaccinated individuals vaccination Vaccine Vaccine breakthrough vaccine strain variants of concern Viral load Virological Virus neutralization wildtype [DOI] 10.1016/j.cmi.2021.11.010 PMC 바로가기 [Article Type] Multicenter Study