Proline-specific peptidase activities (DPP4, PRCP, FAP and PREP) in plasma of hospitalized COVID-19 patients입원한 COVID-19 환자의 혈장에서 프롤린 특이적 펩티다제 활성(DPP4, PRCP, FAP 및 PREP)Article Published on 2022-06-012022-09-11 Journal: Clinica chimica acta; international journal of cli [Category] MERS, 바이오마커, 진단, [키워드] Activation activities activity Alpha Biomarker changes in collected coronavirus COVID-19 COVID-19 patient COVID-19 patients decrease dipeptidyl peptidase Dipeptidyl peptidase 4 discharge DPP4 dysregulated dysregulation elevated FAP feature fibroblast Fibroblast activation protein alpha Follow-up healthy control healthy controls Hospital admission Hospital stay Hospitalization hospitalized COVID-19 patient hospitalized COVID-19 patients immune system investigated pathophysiological patients peptidase plasma PRCP PrEP proline Prolyl oligopeptidase Prolylcarboxypeptidase. Protein remained Sepsis Septic shock significantly significantly increased significantly lower utility were measured while [DOI] 10.1016/j.cca.2022.03.005 PMC 바로가기 [Article Type] Article
Dynamics of anti-Spike IgG antibody level after the second BNT162b2 COVID-19 vaccination in health care workers의료 종사자의 두 번째 BNT162b2 COVID-19 예방 접종 후 항-스파이크 IgG 항체 수준의 역학Article Published on 2022-06-012022-09-12 Journal: Journal of infection and chemotherapy : official j [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] addition Adverse reaction age alcohol allergies allergy anti-Spike IgG Anti-spike IgG antibody anti-spike IgG level anti-spike IgG levels Antibody titer association BMI BNT162b2 categories correlation country COVID-19 COVID-19 vaccination COVID-19 vaccines cross-sectional dose Dynamics evaluate Fever geometric mean titer Health care worker IgG IgG antibody Japanese observation Older Older age participant remained second vaccination Sex Side effect significantly significantly lower smoking statistically significant vaccination vaccine dose Vaccine-induced immunity was performed were assessed [DOI] 10.1016/j.jiac.2022.02.024 PMC 바로가기 [Article Type] Article
The potential impact of COVID-19 on thyroid gland volumes among COVID-19 survivorsCOVID-19 생존자의 갑상선 양에 대한 COVID-19의 잠재적 영향Article Published on 2022-06-012022-09-11 Journal: Endocrine [Category] COVID19(2023년), SARS, 치료기술, [키워드] acute COVID-19 acute infection antibody asked assessments blood test blood tests calculation Control control subject convenience sampling COVID COVID-19 Effect ellipsoid Endocrine endocrine system enrolled euthyroid evaluated groups healthy controls healthy subjects investigated median Mild no significant difference Patient recruited SARS-CoV-2 significant difference significantly lower survivor Survivors Thyroid thyroid function Thyroid function tests thyroid gland Thyroid gland volume. thyroid-stimulating hormone thyroxine triiodothyronine TSH Volume was done was used [DOI] 10.1007/s12020-022-03019-6 PMC 바로가기 [Article Type] Article
SARS-CoV-2 cycle threshold (Ct) values predict future COVID-19 casesSARS-CoV-2 주기 임계값(Ct) 값은 향후 COVID-19 사례를 예측합니다.Article Published on 2022-06-012022-09-11 Journal: Journal of Clinical Virology [Category] COVID19(2023년), SARS, 치료기술, [키워드] analyzed Asymptomatic asymptomatic patient asymptomatic patients Cepheid clinical testing collected correlated COVID-19 COVID-19 case COVID-19 cases Ct value Ct values cycle cycle threshold decrease decreasing determine Epidemiological dynamics facilitate hospital Local Los Angele Los Angeles observation Patient peaking performed predict predicted Predictive representing SARS-CoV-2 SARS-CoV-2 detection significantly lower subsequent threshold Transmission Viral load viral loads Viral RNA would increase [DOI] 10.1016/j.jcv.2022.105153 PMC 바로가기 [Article Type] Article
Humoral response to mRNA-based COVID-19 vaccine in patients with myeloid malignancies골수성 악성종양 환자에서 mRNA 기반 코로나19 백신에 대한 체액 반응Article Published on 2022-06-012022-09-12 Journal: British Journal of Haematology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] acute myeloid leukaemia AML Anti-spike Antibody titre appear comparable COVID-19 COVID-19 vaccine disease HCs healthy control humoral Humoral response Infection lymphoid malignancies malignancy MDs mRNA-based mRNA-based COVID-19 vaccine myelodysplastic syndrome. myeloid malignancies myeloid malignancy no significant difference Patient patients risk SARS-CoV-2 SARS-CoV-2 antibody titre SARS-CoV-2 vaccine significantly lower syndrome therapy Treatment vaccination Vaccine were measured [DOI] 10.1111/bjh.18138 PMC 바로가기 [Article Type] Article
Clinical characterization of COVID-19 breakthrough infections, PhilippinesCOVID-19 돌발 감염의 임상 특성, 필리핀Article Published on 2022-06-012022-09-11 Journal: Journal of Clinical Virology [Category] COVID19(2023년), SARS, 치료기술, [키워드] administration Alpha Asymptomatic Beta booster dose Breakthrough infection breakthrough infections characterized clinical clinically CoronaVac COVID-19 Ct values Delta VOC Evidence HCW HCWs healthcare worker Healthcare workers Inactivated vaccine majority male PCR Philippines risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 transmission sequenced severe cases significantly lower symptomatic viral loads VOCs [DOI] 10.1016/j.jcv.2022.105157 PMC 바로가기 [Article Type] Article
Outcomes of patients with ST-segment myocardial infarction admitted during the COVID-19 pandemic : A prospective, observational study from a tertiary care center in GermanyObservational Study Published on 2022-06-012022-10-05 Journal: Herz [Category] COVID19(2023년), SARS, 임상, [키워드] 30-Day mortality Admission Ausbruch Care clinical cohort study conducted Contact COVID-19 COVID-19 group COVID-19 pandemic Ejection fraction Emergency Emergency medical services English enrolled Epidemiology Germany greater Healthcare professional LVEF medical service medical services Mortality Myocardial Myocardial infarction outbreak outcome outcomes pandemic Patient public health reported SARS-CoV‑2 significantly significantly higher significantly lower significantly more STEMI Support TIMI ventricular were assessed [DOI] 10.1007/s00059-021-05058-7 PMC 바로가기 [Article Type] Observational Study
Pausing methotrexate improves immunogenicity of COVID-19 vaccination in elderly patients with rheumatic diseases메토트렉세이트를 일시 중단하면 류마티스 질환이 있는 노인 환자에서 COVID-19 예방 접종의 면역원성이 향상됩니다.Article Published on 2022-06-012022-09-12 Journal: Annals of the rheumatic diseases [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] age antibody Antibody Response Autoimmune Autoimmune diseases control group correlated COVID-19 COVID-19 vaccination Critical cut-off Elderly patient fixed greater humoral immune response immune response immunosuppressive Immunosuppressive medication IMPROVE medication methotrexate MTX neutralising neutralising antibody nine Older Patient patients older reduce regimen Retrospective study rheumatic disease SARS-CoV-2 antibody SARS-CoV-2 vaccination second vaccination significantly significantly higher significantly lower the antibody response therapy vaccination were measured [DOI] 10.1136/annrheumdis-2021-221876 PMC 바로가기 [Article Type] Article
Gut microbiota composition is associated with SARS-CoV-2 vaccine immunogenicity and adverse events장내 미생물 조성은 SARS-CoV-2 백신 면역원성 및 부작용과 관련이 있습니다.Observational Study Published on 2022-06-012022-09-12 Journal: Gut [Category] COVID19(2023년), MERS, SARS, 임상, 진단, [키워드] adverse event Anti-inflammatory antibody association Bacteria Bacterial baseline Bifidobacterium BNT162b2 BNT162b2 vaccine carbohydrate collected complement conducted CoronaVac COVID-19 COVID-19 vaccinee COVID-19 vaccines Effectiveness enteric bacterial microflora flagella Gut gut microbiota gut microbiota composition high neutralising antibody Host immune response IgG ELISA immune response Inactivated vaccine individual Intervention Linear Discriminant Analysis marker metabolism metagenomic sequencing Microbiome microbiota modulating mRNA vaccine pathway performed positive correlation Prevotella recipient reduced SARS-CoV-2 SARS-CoV-2 vaccine second dose significantly lower Sinovac spike receptor-binding domain Stool subject the vaccine vaccination Vaccine vaccinee vaccinees Virus neutralisation were measured [DOI] 10.1136/gutjnl-2021-326563 PMC 바로가기 [Article Type] Observational Study
Evaluation of Antibody-Dependent Fc-Mediated Viral Entry, as Compared With Neutralization, in SARS-CoV-2 InfectionSARS-CoV-2 감염에서 중화와 비교한 항체 의존성 Fc 매개 바이러스 진입 평가Article Published on 2022-05-312022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 변종, [키워드] Alpha antibody antibody dependent enhancement B.1.1.7 B.1.351 B.1.617.2 Beta characterization collected concern convalescent plasma coronavirus coronavirus – COVID-19 correlated Delta determine evaluated Fc-mediated virus entry functional Gamma HEK293 cell HEK293 cells IgM in vivo individuals infecting neutralization neutralization activity neutralization potency neutralization titer Neutralizing P.1 pandemic peaked plasma plasma dilution plasma IgG plasmas pseudovirus SARS-CoV-2 SARS-CoV-2 pseudovirus SARS-CoV-2 strain SARS-CoV-2 variants significantly significantly higher significantly lower spike (S) protein titers variant variant of concern viral entry virus virus entry viruses VoC waned Washington while [DOI] 10.3389/fimmu.2022.901217 PMC 바로가기 [Article Type] Article