Stratification – Page 22 – Communicable Diseases Research

Stratification of Acute Kidney Injury in COVID-19

Perspective Piece

Published on 2020-12-272022-10-28
Journal: The American Journal of Tropical Medicine and Hygi [Category] COVID-19, MERS, SARS,

Systematic evaluation and external validation of 22 prognostic models among hospitalised adults with COVID-19: an observational cohort study

COVID-19로 입원한 성인의 22개 예후 모델에 대한 체계적인 평가 및 외부 검증: 관찰 코호트 연구

Observational Study

Published on 2020-12-242022-09-06
Journal: The European Respiratory Journal [Category] Communicable Disease, Fulltext, MERS, 임상,

[키워드] 95% CI Admission age analyses AUROC benefit calibration candidate models characteristic Clinical deterioration coronavirus disease Coronavirus disease 2019 COVID-19 demonstrated description Deterioration diagnosis of COVID-19 discrimination Endpoint endpoints evaluated external validation Final final diagnosis hospital hospitalised implementation In-hospital in-hospital mortality Mortality NEWS2 Observational cohort study offered outcome oxygen oxygen saturation participant Patient patient age patients predictor predictors prognostic prognostic model Prognostic models receiver operating characteristic reconstructed room air Stratification systematic review tested threshold univariable widespread with COVID-19
[DOI] 10.1183/13993003.03498-2020 PMC 바로가기 [Article Type] Observational Study

Corticosteroid therapy in critically ill patients with COVID-19: a multicenter, retrospective study

COVID-19 중증 환자의 코르티코스테로이드 요법: 다기관, 후향적 연구

Multicenter Study

Published on 2020-12-182022-09-11
Journal: Critical Care [Category] MERS, 변종,

[키워드] 95% CI adjusted Administered affected Analysis applied association baseline clearance confounding factor confounding factors correlation Corticosteroid corticosteroid treatment Corticosteroids COVID-19 Cox proportional-hazards model Critically ill Critically ill patient critically ill patients Efficacy evaluate ICU ICU admission investigated Logistic regression Marginal structural modeling Methylprednisolone Mortality multicenter not performed outcome Patient performed recruited Result Retrospective study SARS-CoV-2 RNA severe COVID-19 Severe patient severe patients Stratification stratified subgroup analysis therapy treated Treatment variables was performed with COVID-19
[DOI] 10.1186/s13054-020-03429-w PMC 바로가기 [Article Type] Multicenter Study

Improving clinical trial outcomes in amyotrophic lateral sclerosis

Reviews

Published on 2020-12-182022-10-05
Journal: Nature reviews. Neurology [Category] 바이오마커, 신약개발, 임상,

Effects of curcumin-piperine co-supplementation on clinical signs, duration, severity, and inflammatory factors in patients with COVID-19: a structured summary of a study protocol for a randomised controlled trial

COVID-19 환자의 임상 징후, 기간, 중증도 및 염증 요인에 대한 커큐민-피페린 공동 보충제의 효과: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약

Letter

Published on 2020-12-172022-09-10
Journal: Trials [Category] 임상,

[키워드] 1:1 age analyses anticipated Anticoagulant anticoagulant drugs assigned Blinding calculated Capsule clinical Clinical signs Clinical symptoms clinical trial clinical trials Co-supplementation completion conducted control group coronavirus coronavirus disease COVID-19 Curcumin Curcumin-piperine Diagnosis dinner disease Disease duration dissemination double-blind drugs Effect Efficacy element Enrollment exclusion criteria female Gender hospital hospital ward Hospital wards ICU include independent Inflammatory factor inflammatory factors inflammatory mediator Inflammatory mediators Inpatient intensive care intensive care unit Intervention Iran less male maltodextrin matching placebo mediators Medical Sciences number objective outcome Outpatient packaged Parallel Arm participant Patient patients PCR test piperine Placebo placebo-controlled placebo-controlled clinical trial protocol provided randomised randomised controlled trial Randomized Randomly receive Registered registration date registry researcher Sample size sealed sensitivity sequence severity status Stratification Study protocol supplementary material title total sample size Trial Trial registration turmeric university Version Warfarin website
[DOI] 10.1186/s13063-020-04924-9 PMC 바로가기 [Article Type] Letter

Chest x-ray severity score in COVID-19 patients on emergency department admission: a two-centre study

응급실 입원 시 COVID-19 환자의 흉부 엑스레이 중증도 점수: 2개 센터 연구

Observational Study

Published on 2020-12-152022-09-12
Journal: European Radiology Experimental [Category] MERS, SARS, 임상, 진단,

A Novel Risk-Stratification Models of the High-Flow Nasal Cannula Therapy in COVID-19 Patients With Hypoxemic Respiratory Failure

Medicine

Published on 2020-12-082022-10-31
Journal: Frontiers in Medicine [Category] COVID-19,

[키워드] 95% CI 95% confidence interval Accuracy age Analysis analyzed AUC categories Clinical management clinical variable Cohort collected coronavirus disease COVID-19 COVID-19 patient cutoff value demographic elevated failure HFNC HFNC therapy High-flow nasal cannula hospital hospitals hypoxemic IL-6 increased risk information Jin management mechanical ventilation Model nasal novel Older pandemic Patient Platelet predicted Predictive predictor Probability regression analysis respiratory Respiratory failure risk Risk-stratification ROX ROX index sensitivity specificity Stratification stratified subsequent validation the median thrombocytopenia treated were used Wuhan, China
[DOI] 10.3389/fmed.2020.607821 PMC 바로가기 [Article Type] Medicine

A multicenter randomized trial to assess the efficacy of CONvalescent plasma therapy in patients with Invasive COVID-19 and acute respiratory failure treated with mechanical ventilation: the CONFIDENT trial protocol

침습성 COVID-19 및 기계 환기로 치료된 급성 호흡 부전 환자에서 CONvalescent 혈장 요법의 효능을 평가하기 위한 다기관 무작위 시험: CONFIDENT 시험 프로토콜

Study Protocol

Published on 2020-12-072022-09-01
Journal: BMC Pulmonary Medicine [Category] Fulltext, MERS, 임상, 진단,

[키워드] Acute respiratory failure alleviate Analysis approach approval Belgium Blinding board center collected Consent convalescent plasma COVID-19 COVID-19 pandemic data safety monitoring board diagnosed DSMB Efficacy Endpoint Europe Evidence evidence of Evolution of SARS-CoV-2 expected expected mortality frailty funding Health care homogeneous hospital Hospitalized Hypothesis immunization include Inclusion intensive care unit Intention intention to treat Interim Interim analyses International Intervention less mechanical ventilation mechanically ventilated patients monitoring board Mortality multicenter National Neutralizing antibodies neutralizing antibody passive immunization Patient patients patients treated peer-reviewed plasma Pneumonia randomization Randomized randomized trial reached reduce mortality reduction Registered Registration registration number Respiratory failure review risk SARS-CoV-2 SARS-CoV-2 pneumonia severe respiratory failure specific neutralizing antibodies specific neutralizing antibody Standard of care Stratification Symptom the patient therapy TRAIL treated Treatment Trial trial protocol university university hospital
[DOI] 10.1186/s12890-020-01361-x PMC 바로가기 [Article Type] Study Protocol

Laboratory biomarkers associated with COVID-19 severity and management

COVID-19 중증도 및 관리와 관련된 실험실 바이오마커

Article

Published on 2020-12-012022-09-11
Journal: Clinical immunology (Orlando, Fla.) [Category] SARS, 바이오마커,

[키워드] acute respiratory distress acute respiratory distress syndrome Analysis ARDS Biomarker Biomarkers Care correlated COVID-19 CRP cytokine Cytokine storms Cytokines death disease course disease severity Escalation evidence of fraction heterogeneous identification IL-10 IL-6 IL-6 level IL-6 levels Illness severity implicated implication intensive care Intervention Laboratory test Laboratory tests LDH LDH. management Mild multi-organ failure Ordinal Scale oxygen patient triage radiological evidence resource respiratory respiratory distress Respiratory distress syndrome Respiratory failure Respiratory Support sensitivity severe patients severity specificity Stratification Symptom syndrome the WHO therapy Ventilation WHO ordinal scale with COVID-19
[DOI] 10.1016/j.clim.2020.108614 PMC 바로가기 [Article Type] Article

Profile and outcomes of hospitalized patients with COVID-19 at a tertiary institution hospital in Ghana

Original Article

Published on 2020-12-012022-10-31
Journal: Ghana Medical Journal [Category] COVID-19, MERS, SARS,

[키워드] age analysed breathlessness clinical co-morbidity Comorbidity Coronavirus disease 2019 COVID-19 COVID-19 admission Critical determinant Dexamethasone died fatality Fever funding Ghana hospital Hospitalized hospitalized COVID-19 patient hospitalized patient Hydroxychloroquine IMPROVE Increasing KNUST Kwame Nkrumah males management Mild moderate Mortality multivariate logistic regression objective outcome outcomes Patient patients polymerase chain predictor profile Prospective Study real time Result Science severity standardized protocol Stratification sub-Saharan Africa Symptom Systolic blood pressure technology the patient Treatment university with COVID-19
[DOI] 10.4314/gmj.v54i4s.7 PMC 바로가기 [Article Type] Original Article