transcriptional – Page 22 – Communicable Diseases Research

Transcriptional profiling of feline infectious peritonitis virus infection in CRFK cells and in PBMCs from FIP diagnosed cats

Research

Published on 2013-11-092022-10-28
Journal: Virology Journal
[Category] Coronavirus,

Global Analysis of the Sporulation Pathway of Clostridium difficile

Clostridium difficile의 포자 형성 경로에 대한 글로벌 분석

Research Article

Published on 2013-08-082022-09-06
Journal: PLoS Genetics
[Category] Communicable Disease,

[키워드] activated activating Activation Analysis Antibiotics Author B. subtilis Bacillus subtilis Clostridia Clostridium Clostridium difficile Colitis Complication determine determined diagnostic biomarker Diagnostic biomarkers diarrhea expression Factor firmicutes framework function Gene gene product Genes genes encoding gram highlight identify Infection infectious infectious diarrhea lead life-threatening loss-of-function mutation loss-of-function mutations mechanism mutant organism pathogen Pathogenesis performed predicted provide pseudomembranous colitis question recurrence regulate regulated Regulatory regulatory pathway related required responsible Sequencing sigma spore spores sporulation Spread the United State Transcription transcriptional Transmission treat United States whole-genome
[DOI] 10.1371/journal.pgen.1003660 PMC 바로가기 [Article Type] Research Article

High-Resolution Transcriptome Maps Reveal Strain-Specific Regulatory Features of Multiple Campylobacter jejuni Isolates

고해상도 전사체 지도는 여러 Campylobacter jejuni 분리주의 균주 특이적 조절 기능을 보여줍니다

Research Article

Published on 2013-05-162022-09-06
Journal: PLoS Genetics
[Category] Communicable Disease,

[키워드] adaptation addition analysis Analysis analyzed approach Author automated Bacterial bioinformatics Campylobacter Campylobacter jejuni compared consequence conservation conserved contribute CRISPR different DNA ecological niche ecological niches eukaryote eukaryotes facilitate feature functional gastroenteritis Gene Gene Expression Gene regulation Genetic Genome genome sequence Genome sequences genomic variation genomic variations genotypic genotypic variations growth Host hosts humans immune system IMPROVE include integration isolate isolates lead Map maturation modulate Multiple organism Organisms Pathogens pathway phenotypic phenotypic diversity phenotypic variation promoter promoter regions promoters provide Regulation related reveal RNA RNA sequencing RNase similarities similarity small RNA SNP sRNA strain Strains stress conditions time-consuming transcribed transcriptional Transcriptome transcriptomes TSS unique upstream Variation whole-genome
[DOI] 10.1371/journal.pgen.1003495 PMC 바로가기 [Article Type] Research Article

The Tomato Yellow Leaf Curl Virus Resistance Genes Ty-1 and Ty-3 Are Allelic and Code for DFDGD-Class RNA–Dependent RNA Polymerases

토마토 황엽말림 바이러스 내성 유전자 Ty-1 및 Ty-3은 대립유전자이고 DFDGD-Class RNA-Dependent RNA 중합효소에 대한 코드입니다

Research Article

Published on 2013-03-282022-09-06
Journal: PLoS Genetics
[Category] Communicable Disease,

[키워드] allele alleles allelic amplification approach atypical DFDGD motif Author begomovirus begomovirus species Breeding catalytic DLDGD motif catalytic domain cause caused characterized chromosomal region chromosome chromosome 6 class code Combination described different disease geminivirus geminiviruses Gene gene functions genomic region inbred lines induced introgression leaf mapped marker mechanism molecular molecular markers Multiple plant plants RDR RDRα RDRα type RDRγ recent finding recent findings recombinant inbred lines recombination event Region related resistance resistance gene resistance genes resistance mechanism RNA RNA–dependent RNA polymerase shown Solanum chilense Solanum chilense –derived Ty-1 and Ty-3 genes specificity subtropical susceptible these viruses Tobacco Tobacco Rattle Virus tomato Tomato yellow leaf curl virus Tomato Yellow Leaf Curl Virus Disease transcriptional tropical Ty-1 Ty-1 and Ty-3 Ty-1/Ty-3 gene Ty-3 TYLCV virus Virus Disease viruses yellow
[DOI] 10.1371/journal.pgen.1003399 PMC 바로가기 [Article Type] Research Article

The Regulatory Network of Natural Competence and Transformation of Vibrio cholerae

Vibrio cholerae의 자연적 능력 및 변형의 규제 네트워크

Research Article

Published on 2012-06-212022-09-06
Journal: PLoS Genetics
[Category] Communicable Disease,

[키워드] a major Analysis aquatic bacterium aquatic environment assays Author autoinducers Bacteria Bacterial bacterium CAMP carbon Carbon catabolite repression catabolite repression Cell chitin chitinous chitinous exoskeleton colonization Combination competence condition conditions consequence contribute Degradation degradation products dependent on determine developmental different DNA ecological environmental niche environmental reservoirs Evidence Evolution Express expression pattern Extracellular Factor found Gene Gene Expression gene transfer Genes Genetic genetic transformation genomes growth heterogeneity heterogeneous homogeneous horizontal gene Horizontal gene transfer human pathogen immunological detection initiate intracellular signaling investigated involved lead maintenance majority metabolism mode natural Natural competence natural transformation network organism pathogenic phenotype protein level protein levels quantitative RT–PCR quorum-sensing pathways regions regulated regulatory circuit released reporter fusions required signaling cascade signaling pathway single cell level tested TfoX the cells transcriptional transfer transformation V. cholerae Vibrio cholerae western blot Western blot analysis zooplankton
[DOI] 10.1371/journal.pgen.1002778 PMC 바로가기 [Article Type] Research Article

Principles of Carbon Catabolite Repression in the Rice Blast Fungus: Tps1, Nmr1-3, and a MATE–Family Pump Regulate Glucose Metabolism during Infection

쌀 돌풍 곰팡이의 탄소 이화 작용 억제 원리: Tps1, Nmr1-3 및 MATE-Family 펌프가 감염 중 포도당 대사를 조절합니다

Research Article

Published on 2012-05-032022-09-06
Journal: PLoS Genetics
[Category] Communicable Disease,

[키워드] abolishes disease addition Agrobacterium tumefacien Agrobacterium tumefaciens Analysis Author BLAST carbon Carbon catabolite repression carbon metabolism carbon sources Catabolite catabolite repression CCR cell wall cell wall–degrading enzymes component components described disease downstream effective expression filamentous fungi found functional fungal fungal pathogens fungi Genetic genetic regulation Glucose glucose metabolism Glucose-6-phosphate Host identify inactivation Infection infection process inhibitor involved less M. oryzae Magnaporthe MATE protein MATE–family protein Mdt1 mechanism mediators metabolism microbial Mutagenesis Nmr1 Nmr1-3 Nmr1-3 inhibitor proteins nutrient availability organism Pathogenesis pathogenic pathogenicity Pathogens pathway Perturbation physiological principle Protein pump regulate Regulation Regulatory regulatory pathway regulatory pathways repression respond Rice shown sporulation strain sugar target Tps1 transcription factor transcriptional transmembrane Trigger triggers understanding
[DOI] 10.1371/journal.pgen.1002673 PMC 바로가기 [Article Type] Research Article

Interferon Regulatory Factor 8 Regulates Pathways for Antigen Presentation in Myeloid Cells and during Tuberculosis

인터페론 조절 인자 8은 골수 세포 및 결핵 기간 동안 항원 제시 경로를 조절합니다

Research Article

Published on 2011-06-232022-09-06
Journal: PLoS Genetics
[Category] Communicable Disease,

[키워드] (major histocompatibility complex activate Activation allele Analysis Antigen presentation antigen processing Author binding binding site cellular pathway cellular pathways chromatin chromatin immunoprecipitation class Combination component Critical cytokine Defense dendritic cell dendritic cells differentiation early response endomembrane eQTLs expressed expression F2 Factor fixed functional Gene gene transcription GTPase GTPases histocompatibility complex Host–pathogen interaction identify IFNγ IL-12 IL12 immune response Infected Infection interferon gamma interferon regulatory factor interleukin intracellular pathogens intrinsic investigated IRF8 lipopolysaccharide LPS lung tissue lung tissues Lungs Macrophage macrophages major histocompatibility complex maturation member MHC mice Microarray Microarrays microbial motif mutant Mycobacterium tuberculosis myeloid myeloid cell myeloid cells ontogeny Pathogens pathway Pathways presentation priming progenitor cells promoter promoters Proteins pulmonary tuberculosis regulated Regulation represse required resistance to infection resistance to infections significantly Stimulation susceptible target transcript Transcription transcriptional treated Tuberculosis wild-type
[DOI] 10.1371/journal.pgen.1002097 PMC 바로가기 [Article Type] Research Article

Towards a Coronavirus-Based HIV Multigene Vaccine

Research Article

Published on 2006-01-012022-10-31
Journal: Clinical and Developmental Immunology
[Category] Coronavirus,

[키워드] Adults aminopeptidase N anti-HIV drug antigen presenting cell antigens cause CD13 children common cold coronavirus Coronavirus infection costly DC DCs dendritic cell Efficiency enteric diseases expressed feature Gene Gene Expression HCoV 229E Health Heterologous HIV Human human coronavirus 229E humans immunodeficiency virus infected individual infecting Infection Macrophage Molecular biology mucosal surfaces occur pre-existing immunity Prevent Re-infection receptor replaced required RNA second significantly Spread These cells threat transcriptional Transmission Treatment upper respiratory tract vaccination Vaccination strategy Vaccine Vaccines vector Virus-like particle VLPs
[DOI] 10.1080/17402520600579168 PMC 바로가기 [Article Type] Research Article