Structure and Inhibition of the SARS Coronavirus Envelope Protein Ion Channel
Research Article
[키워드] 2003
acute respiratory syndrome
affecting
alteration
Anti-viral drugs
antiviral strategy
Author
binding site
C-terminal
Cell
channel
characterized
common cold
coronavirus
coronavirus protein
described
determined
distribution
drug design
E protein
embryonic kidney
envelope
envelope protein
event
expressed
expressing
feature
form
found
full length
HEK-293
Human
humans
in vitro
inactivation
infect
inhibited
inhibition
Ion
lethal disease
mammalian cell
mammals
membrane
Mild
morphology
N-terminal
NMR
pandemic
Pathogenesis
pharmacological target
platform
produced
Protein
Proteins
provide
reduced
reported
responsible
SARS-CoV
SARS-CoV E
shown
significantly
Structure
supported
transmembrane domain
Validity
variety
viral envelope
viral pathogen
viral replication
virion
virus
viruses
[DOI] 10.1371/journal.ppat.1000511 PMC 바로가기 [Article Type] Research Article
[DOI] 10.1371/journal.ppat.1000511 PMC 바로가기 [Article Type] Research Article